ChemicalBook > CAS DataBase List > C24-Ceramide

C24-Ceramide

Product Name
C24-Ceramide
CAS No.
34435-05-7
Chemical Name
C24-Ceramide
Synonyms
C24 CERAMIDE;LIGNOCERIC CERAMIDE;N-TETRACOSANOYL-D-ERYTHRO-SPHINGOSINE;TETRACOSENAMIDE;C24-D-ERYTHRO-CERAMIDE;N-Lignoceroylsphingosine;N-MYRISTOYL-D-SPHINGOSINE;N-TETRACOSANOYLSPHINGOSINE;N-MYRISTOYL-D-ERYTHRO-SPHINGOSINE;N-((2R,3S,E)-1,3-Dihydroxyoctadec-4-en-2-yl)tetracosanamide
CBNumber
CB8272483
Molecular Formula
C42H83NO3
Formula Weight
650.11
MOL File
34435-05-7.mol
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C24-Ceramide Property

Melting point:
94-96
Boiling point:
750.0±60.0 °C(Predicted)
Density 
0.906±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Sparingly)
form 
Solid
pka
13.54±0.20(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
1mg
Price
$23
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
5mg
Price
$101
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
10mg
Price
$180
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
25mg
Price
$393
Updated
2024/03/01
TRC
Product number
C263450
Product name
C24Ceramide
Packaging
5mg
Price
$90
Updated
2021/12/16
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C24-Ceramide Chemical Properties,Usage,Production

Description

Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase. C24 Ceramide (d18:1/24:0) is one of the most abundant naturally occurring ceramides. Ceramides mediate many diverse biological activities, as has been demonstrated in studies utilizing cell-permeable ceramide analogs. A few of the processes regulated by ceramides include apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain.

Chemical Properties

Crystalline Solid

Uses

Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of phospholipase C, appropriately named sphingomyelinase.

Definition

ChEBI: N-tetracosanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as tetracosanoyl. It has a role as a mouse metabolite. It is a N-acylsphingosine, a Cer(d42:1) and a N-(very-long-chain fatty acyl)-sphingoid base. It is functionally related to a tetracosanoic acid.

References

[1] MING GU . Ceramide Profiling of Complex Lipid Mixtures by Electrospray Ionization Mass Spectrometry[J]. Analytical biochemistry, 1997, 244 2: Pages 347-356. DOI: 10.1006/abio.1996.9915
[2] R B CLAYTON. Stimulation of erythroblast maturation in vitro by sphingolipids.[J]. Journal of Lipid Research, 1974, 15 6: 557-562.
[3] W KRIVIT  S H. Identification and quantitation of free ceramides in human platelets.[J]. Journal of Lipid Research, 1972, 13 4: 525-530.
[4] TESTI R. Sphingomyelin breakdown and cell fate[J]. Trends in Biochemical Sciences, 1996, 21 12: Pages 468-471. DOI: 10.1016/s0968-0004(96)10056-6
[5] N AUGé. The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation.[J]. The Journal of Biological Chemistry, 1996, 271 32: 19251-19255. DOI: 10.1074/jbc.271.32.19251
[6] T I GUDZ  C L H  K Y Tserng. Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide.[J]. The Journal of Biological Chemistry, 1997, 272 39: 24154-24158. DOI: 10.1074/jbc.272.39.24154

C24-Ceramide Preparation Products And Raw materials

Raw materials

Preparation Products

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C24-Ceramide Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
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69
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
42446
Advantage
60
Yichang Zhongyitai Trading Co., Ltd.
Tel
0717-6449896 13886658719
Fax
0717-6558598
Email
root@zhongyitai.com
Country
China
ProdList
1978
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Alfa Chemistry
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1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
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Shanghai Renshi Pharmatech Co., LTD
Tel
021-61150625 17721318029
Fax
021-26018649
Email
info@renshipharma.com
Country
China
ProdList
161
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55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
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60
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
Advantage
58

34435-05-7, C24-CeramideRelated Search:


  • C24-D-ERYTHRO-CERAMIDE
  • C24 CERAMIDE
  • LIGNOCERIC CERAMIDE
  • TETRACOSENAMIDE
  • N-TETRACOSANOYLSPHINGOSINE
  • N-TETRACOSANOYL-D-ERYTHRO-SPHINGOSINE
  • N-MYRISTOYL-D-ERYTHRO-SPHINGOSINE
  • N-MYRISTOYL-D-SPHINGOSINE
  • N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-Tetracosanamide
  • N-Lignoceroylsphingosine
  • Tetracosanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
  • N-((2R,3S,E)-1,3-Dihydroxyoctadec-4-en-2-yl)tetracosanamide
  • 34435-05-7
  • Mixed Fatty Acids
  • Activators
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Inhibitors
  • Protein Kinase Inhibitors and Activators