ChemicalBook > CAS DataBase List > C24-Ceramide

C24-Ceramide

Product Name
C24-Ceramide
CAS No.
34435-05-7
Chemical Name
C24-Ceramide
Synonyms
C24 CERAMIDE;LIGNOCERIC CERAMIDE;N-TETRACOSANOYL-D-ERYTHRO-SPHINGOSINE;TETRACOSENAMIDE;C24-D-ERYTHRO-CERAMIDE;N-Lignoceroylsphingosine;N-MYRISTOYL-D-SPHINGOSINE;N-TETRACOSANOYLSPHINGOSINE;N-MYRISTOYL-D-ERYTHRO-SPHINGOSINE;N-((2R,3S,E)-1,3-Dihydroxyoctadec-4-en-2-yl)tetracosanamide
CBNumber
CB8272483
Molecular Formula
C42H83NO3
Formula Weight
650.11
MOL File
34435-05-7.mol
More
Less

C24-Ceramide Property

Melting point:
94-96
Boiling point:
750.0±60.0 °C(Predicted)
Density 
0.906±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer
solubility 
Chloroform (Sparingly)
form 
Solid
pka
13.54±0.20(Predicted)
color 
White to Off-White
More
Less

Hazard and Precautionary Statements (GHS)

More
Less

N-Bromosuccinimide Price

Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
1mg
Price
$23
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
5mg
Price
$101
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
10mg
Price
$180
Updated
2024/03/01
Cayman Chemical
Product number
62535
Product name
Lignoceric Ceramide
Purity
≥98%
Packaging
25mg
Price
$393
Updated
2024/03/01
Usbiological
Product number
C2777-79
Product name
C14 Ceramide
Packaging
10mg
Price
$326
Updated
2021/12/16
More
Less

C24-Ceramide Chemical Properties,Usage,Production

Description

Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of PLC, appropriately named sphingomyelinase. C24 Ceramide (d18:1/24:0) is one of the most abundant naturally occurring ceramides. Ceramides mediate many diverse biological activities, as has been demonstrated in studies utilizing cell-permeable ceramide analogs. A few of the processes regulated by ceramides include apoptosis, cell differentiation, proliferation of smooth muscle cells, and inhibition of the mitochondrial respiratory chain.

Chemical Properties

Crystalline Solid

Uses

Production of ceramide occurs upon hydrolysis of sphingomyelin by a specific isoform of phospholipase C, appropriately named sphingomyelinase.

Definition

ChEBI: N-tetracosanoylsphingosine is a N-acylsphingosine in which the ceramide N-acyl group is specified as tetracosanoyl. It has a role as a mouse metabolite. It is a N-acylsphingosine, a Cer(d42:1) and a N-(very-long-chain fatty acyl)-sphingoid base. It is functionally related to a tetracosanoic acid.

References

[1] MING GU . Ceramide Profiling of Complex Lipid Mixtures by Electrospray Ionization Mass Spectrometry[J]. Analytical biochemistry, 1997, 244 2: Pages 347-356. DOI: 10.1006/abio.1996.9915
[2] R B CLAYTON. Stimulation of erythroblast maturation in vitro by sphingolipids.[J]. Journal of Lipid Research, 1974, 15 6: 557-562.
[3] W KRIVIT  S H. Identification and quantitation of free ceramides in human platelets.[J]. Journal of Lipid Research, 1972, 13 4: 525-530.
[4] TESTI R. Sphingomyelin breakdown and cell fate[J]. Trends in Biochemical Sciences, 1996, 21 12: Pages 468-471. DOI: 10.1016/s0968-0004(96)10056-6
[5] N AUGé. The sphingomyelin-ceramide signaling pathway is involved in oxidized low density lipoprotein-induced cell proliferation.[J]. The Journal of Biological Chemistry, 1996, 271 32: 19251-19255. DOI: 10.1074/jbc.271.32.19251
[6] T I GUDZ  C L H  K Y Tserng. Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide.[J]. The Journal of Biological Chemistry, 1997, 272 39: 24154-24158. DOI: 10.1074/jbc.272.39.24154

C24-Ceramide Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

C24-Ceramide Suppliers

Alfa Chemistry
Tel
1-516-6625404
Fax
1-516-927-0118
Email
support@alfa-chemistry.com
Country
United States
ProdList
9171
Advantage
60
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
United States Biological
Tel
--
Fax
--
Email
sales@advtechind.com
Country
United States
ProdList
6075
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
United States Biological
Tel
--
Fax
--
Email
chemicals@usbio.net
Country
United States
ProdList
6214
Advantage
80
Medical Isotopes
Tel
--
Fax
--
Email
stohler@medicalisotopes.com
Country
United States
ProdList
6181
Advantage
68
INDOFINE Chemical Company, Inc.
Tel
--
Fax
--
Email
chemical@indofinechemical.com
Country
United States
ProdList
6176
Advantage
69
Avanti Polar Lipids, Inc.
Tel
--
Fax
--
Email
info@avantilipids.com
Country
United States
ProdList
610
Advantage
79
Matreya LLC
Tel
--
Fax
--
Email
customerservice@matreya.com
Country
United States
ProdList
384
Advantage
62

34435-05-7, C24-CeramideRelated Search:


  • C24-D-ERYTHRO-CERAMIDE
  • C24 CERAMIDE
  • LIGNOCERIC CERAMIDE
  • TETRACOSENAMIDE
  • N-TETRACOSANOYLSPHINGOSINE
  • N-TETRACOSANOYL-D-ERYTHRO-SPHINGOSINE
  • N-MYRISTOYL-D-ERYTHRO-SPHINGOSINE
  • N-MYRISTOYL-D-SPHINGOSINE
  • N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-Tetracosanamide
  • N-Lignoceroylsphingosine
  • Tetracosanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-
  • N-((2R,3S,E)-1,3-Dihydroxyoctadec-4-en-2-yl)tetracosanamide
  • 34435-05-7
  • Mixed Fatty Acids
  • Activators
  • Fatty Acid Derivatives & Lipids
  • Glycerols
  • Inhibitors
  • Protein Kinase Inhibitors and Activators