E-7449

Product Name: E-7449
CAS No.: 1140964-99-3
Chemical Name: E-7449
Synonyms: E7449;E-7449;E7449;E 7449;UNII-9X5A2QIA7C;Stenoparib (E7449);Stenoparib, E7449, 2X-121;Stenoparib（E7449，2X-121，MGI25036）;E7449,PARP,Inhibitor,inhibit,E 7449,E-7449,poly ADP ribose polymerase;8-(Isoindolin-2-ylmethyl)-1,2-dihydro-3H-pyridazino[3,4,5-de]quinazolin-3-one;8-(1,3-dihydro-isoindol-2-ylmethyl)-2,9-dihydro-1,2,7,9-tetraaza-phenalen-3-one
CBNumber: CB82729361
Molecular Formula: C18H15N5O
Formula Weight: 317.34
MOL File: 1140964-99-3.mol

More

Less

E-7449 Property

Density: 1.53±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO:0.2(Max Conc. mg/mL);0.63(Max Conc. mM)
form: A crystalline solid
pka: 9.51±0.20(Predicted)
color: Light yellow to yellow

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 21658
Product name: E7449
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21658
Product name: E7449
Purity: ≥98%
Packaging: 5mg
Price: $145
Updated: 2024/03/01

Cayman Chemical

Product number: 21658
Product name: E7449
Purity: ≥98%
Packaging: 10mg
Price: $275
Updated: 2024/03/01

Cayman Chemical

Product number: 21658
Product name: E7449
Purity: ≥98%
Packaging: 25mg
Price: $571
Updated: 2024/03/01

Usbiological

Product number: 447764
Product name: E 7449
Packaging: 1mg
Price: $468
Updated: 2021/12/16

More

Less

E-7449 Chemical Properties,Usage,Production

Uses

E 7449 is a dual inhibitor of PARP1/2 and tankyrase1/2 exhibits anti-tumor activity in BRCA-deficient in vivo models. PARP1/2 and tankyrase1/2 are involved with DNA damage and canonical Wnt/β-catenin signaling, respectively.

E-7449 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

E-7449 Suppliers

China 68 United States 8 Global 76

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Musechem

Tel: +1-800-259-7612
Fax: +1-800-259-7612
Email: info@musechem.com
Country: United States
ProdList: 4660
Advantage: 60

InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
ProdList: 6391
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 57505
Advantage: 58

TargetMol Chemicals Inc.

Tel
Email: support@targetmol.com
Country: United States
ProdList: 38631
Advantage: 58

United States Biological

Tel: --
Fax: --
Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

Cayman Chemical Company

Tel: --
Fax: --
Email: cayman@caymanchem.com
Country: United States
ProdList: 6213
Advantage: 81

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

1140964-99-3, E-7449Related Search:

E7449

E-7449

8-(1,3-dihydro-isoindol-2-ylmethyl)-2,9-dihydro-1,2,7,9-tetraaza-phenalen-3-one

E7449;E 7449

3H-Pyridazino[3,4,5-de]quinazolin-3-one, 8-[(1,3-dihydro-2H-isoindol-2-yl)methyl]-1,2-dihydro-

UNII-9X5A2QIA7C

Stenoparib (E7449)

E7449,PARP,Inhibitor,inhibit,E 7449,E-7449,poly ADP ribose polymerase

Stenoparib, E7449, 2X-121

Stenoparib（E7449，2X-121，MGI25036）

8-(Isoindolin-2-ylmethyl)-1,2-dihydro-3H-pyridazino[3,4,5-de]quinazolin-3-one

1140964-99-3