BLU9931

Product Name: BLU9931
CAS No.: 1538604-68-0
Chemical Name: BLU9931
Synonyms: BLU;BLU9931;LM-3610;CS-1699;BLU-9931;BLU 9931;LM-3610; BLU9931;BLU 9931;BLU-9931;BLU-9931;BLU 9931;BLU9931;BLU9931, 98%, a potent, selective, and irreversible FGFR4 inhibitor
CBNumber: CB82741679
Molecular Formula: C26H22Cl2N4O3
Formula Weight: 509.38
MOL File: 1538604-68-0.mol

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BLU9931 Property

Density: 1.361±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: ≥50.9 mg/mL in DMSO; insoluble in H2O; ≥2.53 mg/mL in EtOH with gentle warming and ultrasonic
form: Powder
pka: 13.15±0.70(Predicted)
color: Off-white to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 18405
Product name: BLU9931
Purity: ≥98%
Packaging: 1mg
Price: $49
Updated: 2024/03/01

Cayman Chemical

Product number: 18405
Product name: BLU9931
Purity: ≥98%
Packaging: 5mg
Price: $216
Updated: 2024/03/01

Cayman Chemical

Product number: 18405
Product name: BLU9931
Purity: ≥98%
Packaging: 10mg
Price: $380
Updated: 2024/03/01

Cayman Chemical

Product number: 18405
Product name: BLU9931
Purity: ≥98%
Packaging: 25mg
Price: $711
Updated: 2024/03/01

AK Scientific

Product number: 4064DW
Product name: N-[2-[[6-(2,6-Dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl]amino]-3-methylphenyl]prop-2-enamide
Packaging: 10mg
Price: $185
Updated: 2021/12/16

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BLU9931 Chemical Properties,Usage,Production

Definition

BLU9931 is a potent, highly selective, and irreversible fibroblast growth factor receptor 4 (FGFR4) inhibitor with an IC50 of 3 nM and a Kd of 6 nM. BLU9931 has significant antitumor activity. BLU9931 makes a covalent bond with Cys552 within the ATP-binding pocket of FGFR4, which is not present in FGFR1-3. BLU9931 inhibited gastric cancer cell growth in a transplanted mouse model[1].

References

[1] Norihiko Sasaki. “FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer.” Cancers (2020).

BLU9931 Preparation Products And Raw materials

Raw materials

Preparation Products

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BLU9931 Suppliers

China 123 India 1 United States 11 Global 135

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

Shanghai Topbiochem Technology Co., Ltd

Tel: 021-58170097
Email: info@topbiochem.com
Country: China
ProdList: 9458
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 17501653715
Email: xingui2022@126.com
Country: China
ProdList: 10015
Advantage: 58

Shanghai Synteam Biochem CO.,ltd

Tel: +86-021-58380978 +86-18017016373
Fax: 021-58380978
Email: info@systeambc.com
Country: China
ProdList: 942
Advantage: 50

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

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View Lastest Price from BLU9931 manufacturers

Career Henan Chemical Co

Product: BLU 9931 1538604-68-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000KGS
Release date: 2019-12-31

1538604-68-0, BLU9931Related Search:

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BLU 9931

BLU9931

BLU-9931

LM-3610

LM-3610; BLU9931

2-Propenamide,N-[2-[[6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]-

BLU 9931;BLU-9931

BLU9931, 98%, a potent, selective, and irreversible FGFR4 inhibitor

N-(2-((6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)-3-methylphenyl)acrylamide

N-[2-[[6-(2,6-Dichloro-3,5-dimethoxyphenyl)-2-quinazolinyl]amino]-3-methylphenyl]-2-propenamide

BLU

CS-1699

BLU-9931;BLU 9931;BLU9931

1538604-68-0

C26H22Cl2N4O3

Inhibitors