ChemicalBook > CAS DataBase List > 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine

Product Name
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine
CAS No.
1228780-72-0
Chemical Name
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine
Synonyms
Abt199 int3;Venetoclax Intermediate 1;1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl...;1-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazine;1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine;(4-(2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine;1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]Piperazine;Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-;"1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1- en-1-yl]methyl}piperazine" ;1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methy)piperazine
CBNumber
CB82742388
Molecular Formula
C19H27ClN2
Formula Weight
318.88
MOL File
1228780-72-0.mol
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1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine Property

Boiling point:
421.2±45.0 °C(Predicted)
Density 
1.072±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
pka
9.21±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C596078
Product name
1-((4''-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1''-biphenyl]-2-yl)methyl)piperazine
Packaging
500mg
Price
$310
Updated
2021/12/16
SynQuest Laboratories
Product number
3H31-5-2M
Product name
1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazinedihydrochloridesalt
Purity
97.0%
Packaging
1g
Price
$490
Updated
2021/12/16
SynQuest Laboratories
Product number
3H31-5-2M
Product name
1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazinedihydrochloridesalt
Purity
97.0%
Packaging
5G
Price
$1290
Updated
2021/12/16
AK Scientific
Product number
0021AP
Product name
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine
Packaging
25g
Price
$1584
Updated
2021/12/16
SynQuest Laboratories
Product number
3H31-5-2M
Product name
1-{[2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazinedihydrochloridesalt
Purity
97.0%
Packaging
250mg
Price
$190
Updated
2021/12/16
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1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine Chemical Properties,Usage,Production

Uses

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine is an intermediate of Venetoclax (ABT-199) which is a small, oral chemical molecule used for the treatment of chronic lymphocytic leukemia (CLL) associated with a specific chromosomal abnormality.

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine Suppliers

China 184 India 3 United States 4 Global 191
Changzhou Nuobailang Biomedical Technology Co., Ltd.
Tel
13861006441
Email
780864642@qq.com
Country
China
ProdList
23
Advantage
58
NANJING ZENJI PHARMACEUTICALS
Tel
025-58231105-8151 15190133791;
Email
marketing@zenjipharma.com
Country
China
ProdList
437
Advantage
58
Nanjing Becas pharmatech Ltd.
Tel
13912903754
Email
info@becaspharma.com
Country
China
ProdList
2427
Advantage
58
Nanjing Lebang Pharmaceutical Technology Co., Ltd
Tel
18860950986
Email
tangmanman@lebangpharma.com
Country
China
ProdList
566
Advantage
58
EVERSHINE CHEMICAL CO., LIMITED
Tel
0571-58120272 17185714011
Email
3506894070@qq.com
Country
China
ProdList
85
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
Synches Co., Ltd.
Tel
021-53292253
Fax
021-53292253
Email
biz@synches.com
Country
China
ProdList
199
Advantage
64
Shenzhen HwaGen Pharmaceutical Co.,Ltd
Tel
18927339850
Fax
0752-5319394
Email
xiaodong.shi@rafflespt.com
Country
China
ProdList
238
Advantage
58
SHANGHAI YINGRUI CHEMICAL TECHNOLOGY CO.,LTD.
Tel
021-34666753 13311639313
Fax
+86-21-34979012
Email
info@shyrchem.com
Country
China
ProdList
571
Advantage
55
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View Lastest Price from 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine manufacturers

Hangzhou ICH Biofarm Co., Ltd
Product
1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine 1228780-72-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
200kg
Release date
2023-06-30
Hebei Mingeng Biotechnology Co., Ltd
Product
Venetoclax Intermediate 1 1228780-72-0
Price
US $150.00/ASSAYS
Min. Order
10g
Purity
>99%
Supply Ability
500kg/month
Release date
2021-12-23
Zhuozhou Wenxi import and Export Co., Ltd
Product
1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine 1228780-72-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-06-26

1228780-72-0, 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazineRelated Search:

1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine dihydrochloride 2-[(1H-Pyrrolo[2,3-b]pyridin-5-yl)oxy]-4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl]methyl]piperazin-1-yl]benzoic acid 1H-Pyrrolo[2,3-b]pyridin-5-ol, 1-[tris(1-methylethyl)silyl]- ABT-199 Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 3-nitro-4-((tetrahydro-2H-pyran-4-yl)MethylaMino)benzenesulfonaMide 4'-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carbaldehyde

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  • 1228780-72-0