Durvalumab

Product Name: Durvalumab
CAS No.: 1428935-60-7
Chemical Name: Durvalumab
Synonyms: MEDI4736;Durvalumab;Research Grade Durvalumab;Research Grade Durvalumab(DHJ70102)
CBNumber: CB82744216
Formula Weight: 0
MOL File: Mol file

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Durvalumab Property

storage temp.: Store at 4°C, do not freeze
solubility: Soluble in DMSO
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0030858
Product name: Durvalumab
Purity: 99.60%
Packaging: 1mg
Price: $280
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0018422
Product name: MEDI-4736
Purity: 95.00%
Packaging: 5MG
Price: $504.9
Updated: 2021/12/16

ChemScene

Product number: CS-0030858
Product name: Durvalumab
Purity: 99.60%
Packaging: 5mg
Price: $670
Updated: 2021/12/16

ChemScene

Product number: CS-0030858
Product name: Durvalumab
Purity: 99.60%
Packaging: 25mg
Price: $2550
Updated: 2021/12/16

ChemScene

Product number: CS-0030858
Product name: Durvalumab
Purity: 99.60%
Packaging: 50mg
Price: $4080
Updated: 2021/12/16

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Durvalumab Chemical Properties,Usage,Production

Uses

Durvalumab is used to treat non-small cell lung cancer (NSCLC) that spread to nearby tissues and cannot be removed by surgery but has not worsened after being treated with other chemotherapy medications and radiation treatments. Durvalumab injection is also used in combination with etoposide (Etopophos) and either carboplatin or cisplatin to treat extensive-stage small cell lung cancer (ES-SCLC) in adults whose cancer has spread throughout the lungs and to other parts of the body.

Side effects

swelling of your arms or legs;constipation;hair loss

in vivo

Durvalumab (0.1-5 mg/kg, intraperitoneal injection, twice a week, three weeks) suppresses human tumor growth in mouse models through T cell inhibition^[1].

Animal Model:	NOD/SCID mice with HPAC tumor, following coimplantation of primary human T cells; NOD/SCID mice with A375 tumor, following coimplantation of primary human T cells^[2]
Dosage:	5, 1, 0.1, and 0.01 mg/kg for NOD/SCID mice with HPAC tumor; 5, 1, and 0.1 mg/kg for NOD/SCID mice with A375 tumor
Administration:	Administration i.p.; twice per week; for 3 weeks
Result:	Significantly inhibited the tumor growth of both HPAC and A375 xenografts compared with an isotype-matched control antibody.

Durvalumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Durvalumab Suppliers

China 35 United States 3 Global 38

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Durvalumab

MEDI4736

Research Grade Durvalumab(DHJ70102)

Research Grade Durvalumab

1428935-60-7