ChemicalBook > CAS DataBase List > 2,4-BIS(TRIFLUOROMETHYL)ANILINE

2,4-BIS(TRIFLUOROMETHYL)ANILINE

Product Name
2,4-BIS(TRIFLUOROMETHYL)ANILINE
CAS No.
367-71-5
Chemical Name
2,4-BIS(TRIFLUOROMETHYL)ANILINE
Synonyms
2,4-Ditrifluoromethylaniline;2,4-BIS(TRIFLUOROMETHYL)ANILINE;2,4-Bis(trifluoromethyl)aniline98%;2,4-Bis(trifluoromethyl)aniline 98%;2,4-Bis(trifluoromethyl)aniline 97+%;BenzenaMine,2,4-bis(trifluoroMethyl)-;alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-2,4-xylidine
CBNumber
CB8274700
Molecular Formula
C8H5F6N
Formula Weight
229.12
MOL File
367-71-5.mol
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2,4-BIS(TRIFLUOROMETHYL)ANILINE Property

Boiling point:
50°C 0,4mm
Density 
1.443±0.06 g/cm3(Predicted)
refractive index 
1.4372
Flash point:
50°C/0.4mm
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
solid
pka
-0.37±0.10(Predicted)
Specific Gravity
1.44
Appearance
Colorless to light yellow Liquid
BRN 
3319910
InChI
InChI=1S/C8H5F6N/c9-7(10,11)4-1-2-6(15)5(3-4)8(12,13)14/h1-3H,15H2
InChIKey
UIWVOUBVGBJRNP-UHFFFAOYSA-N
SMILES
C1(N)=CC=C(C(F)(F)F)C=C1C(F)(F)F
CAS DataBase Reference
367-71-5(CAS DataBase Reference)
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Safety

Hazard Codes 
T,Xn,Xi
Risk Statements 
23/24/25-33-36/38-36/37/38-20/21/22-52-36
Safety Statements 
36/37/39-45-36-26
RIDADR 
2810
Hazard Note 
Toxic
HazardClass 
6.1
PackingGroup 
III
HS Code 
2921420090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
T900520
Product name
2,4-Bis(trifluoromethyl)aniline
Packaging
500mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
005838
Product name
2,4-Bis(trifluoromethyl)aniline
Packaging
1g
Price
$49
Updated
2021/12/16
AK Scientific
Product number
W5790
Product name
2,4-Ditrifluoromethylaniline
Packaging
1g
Price
$116
Updated
2021/12/16
Matrix Scientific
Product number
005838
Product name
2,4-Bis(trifluoromethyl)aniline
Packaging
5g
Price
$144
Updated
2021/12/16
Apolloscientific
Product number
PC2007
Product name
2,4-Bis(trifluoromethyl)aniline
Packaging
5g
Price
$196
Updated
2021/12/16
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2,4-BIS(TRIFLUOROMETHYL)ANILINE Chemical Properties,Usage,Production

Synthesis

887144-94-7

455-14-1

367-71-5

The general procedure for the synthesis of 2,4-bis(trifluoromethyl)aniline from 1-(trifluoromethyl)-1,2-phenyliodonyl-3(1H)-one and p-trifluoromethylaniline is as follows: in this embodiment, p-trifluoromethylaniline is used as the aromatic amine, and the rest of the reaction and post-treatment steps are the same as in embodiment 28. The specific reaction conditions were as follows: 1-(trifluoromethyl)-1,2-phenyliodono-3(1H)-one (0.5 mmol, 1.0 eq.), p-trifluoromethylaniline (1.5 mmol, 3.0 eq.), nickel hydroxide (10 μmol), and potassium carbonate (1.5 mmol, 3.0 eq.) were dissolved in DMSO (2 mL), and the reaction was carried out for 2 hr at 35 °C. After the reaction was completed, post-treatment was carried out according to the method in Example 1.

References

[1] Organic Letters, 2018, vol. 20, # 13, p. 3732 - 3735
[2] Patent: CN108503552, 2018, A. Location in patent: Paragraph 0142-0146

2,4-BIS(TRIFLUOROMETHYL)ANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2,4-BIS(TRIFLUOROMETHYL)ANILINE manufacturers

Career Henan Chemical Co
Product
2,4-BIS(TRIFLUOROMETHYL)ANILINE 367-71-5
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25