4-(4-Morpholinobutylthio)phenol

Product Name: 4-(4-Morpholinobutylthio)phenol
CAS No.: 57055-82-0
Chemical Name: 4-(4-Morpholinobutylthio)phenol
Synonyms: MoTP;33N14;4-(4-Morpholinobutylthio)phenol;4-(4-morpholin-4-ylbutylsulfanyl)phenol;Phenol, 4-[[4-(4-morpholinyl)butyl]thio]-
CBNumber: CB82750473
Molecular Formula: C14H21NO2S
Formula Weight: 267.39
MOL File: 57055-82-0.mol

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4-(4-Morpholinobutylthio)phenol Property

storage temp.: -20°C
solubility: DMSO: ≥80mg/mL
form: powder
color: white to tan
Stability:: Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0047
Product name: MoTP
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $102
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0047
Product name: MoTP
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $320
Updated: 2024/03/01

Cayman Chemical

Product number: 15204
Product name: MoTP
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 15204
Product name: MoTP
Purity: ≥98%
Packaging: 5mg
Price: $86
Updated: 2024/03/01

Cayman Chemical

Product number: 15204
Product name: MoTP
Purity: ≥98%
Packaging: 10mg
Price: $139
Updated: 2024/03/01

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4-(4-Morpholinobutylthio)phenol Chemical Properties,Usage,Production

Description

MoTP (57055-82-0) specifically ablates zebrafish larval melanocytes. Melanocytotoxicity is dependent on tyrosinase activity.1,2 MoTP is a useful tool for elucidating melanocyte stem cell regeneration, recruitment and maintenance.3-5

References

1) Yang et al. (2006), Small molecule-induced ablation and subsequent regeneration of larval zebrafish melanocytes; Development, 133 3563 2) Yang et al. (2007), Mutations in gfpt1 and skiv2I2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish; PLoS Genet., 3 e88 3) Hultman et al. (2009), Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes; PLoS Genet., 5 e1000544 4) Hultman et al. (2010), Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern; Dev. Biol., 337 425 5) Hultman et al. (2008), Small molecule modifier screen for kit-dependent functions in zebrafish embryonic melanocytes; Zebrafish, 5 279

4-(4-Morpholinobutylthio)phenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-Morpholinobutylthio)phenol Suppliers

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57055-82-0, 4-(4-Morpholinobutylthio)phenolRelated Search:

Prostaglandin E2 ISX 9 IWP-2 24(S),25-Epoxycholesterol (not deuterated)

33N14

4-(4-Morpholinobutylthio)phenol

MoTP

4-(4-morpholin-4-ylbutylsulfanyl)phenol

Phenol, 4-[[4-(4-morpholinyl)butyl]thio]-

57055-82-0