ChemicalBook > CAS DataBase List > 4-(4-Morpholinobutylthio)phenol

4-(4-Morpholinobutylthio)phenol

Product Name
4-(4-Morpholinobutylthio)phenol
CAS No.
57055-82-0
Chemical Name
4-(4-Morpholinobutylthio)phenol
Synonyms
MoTP;33N14;4-(4-Morpholinobutylthio)phenol;4-(4-morpholin-4-ylbutylsulfanyl)phenol;Phenol, 4-[[4-(4-morpholinyl)butyl]thio]-
CBNumber
CB82750473
Molecular Formula
C14H21NO2S
Formula Weight
267.39
MOL File
57055-82-0.mol
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4-(4-Morpholinobutylthio)phenol Property

storage temp. 
-20°C
solubility 
DMSO: ≥80mg/mL
form 
powder
color 
white to tan
Stability:
Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0047
Product name
MoTP
Purity
≥98% (HPLC)
Packaging
5mg
Price
$99.75
Updated
2025/07/31
Sigma-Aldrich
Product number
SML0047
Product name
MoTP
Purity
≥98% (HPLC)
Packaging
25mg
Price
$329
Updated
2025/07/31
Cayman Chemical
Product number
15204
Product name
MoTP
Purity
≥98%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
15204
Product name
MoTP
Purity
≥98%
Packaging
5mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
15204
Product name
MoTP
Purity
≥98%
Packaging
10mg
Price
$139
Updated
2024/03/01
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4-(4-Morpholinobutylthio)phenol Chemical Properties,Usage,Production

Description

MoTP (57055-82-0) specifically ablates zebrafish larval melanocytes. Melanocytotoxicity is dependent on tyrosinase activity.1,2 MoTP is a useful tool for elucidating melanocyte stem cell regeneration, recruitment and maintenance.3-5

Uses

MoTP is a specific platelet activating factor receptor antagonist and can induce melanocyte ablation. MoTP can be used for the research of cancer.

References

[1] CHAO-TSUNG YANG  Stephen L J. Small molecule-induced ablation and subsequent regeneration of larval zebrafish melanocytes.[J]. Development, 2006, 133 18: 3563-3573. DOI:10.1242/dev.02533
[2] CHAO-TSUNG YANG. Mutations in gfpt1 and skiv2l2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish.[J]. PLoS Genetics, 2007, 3 6: e88. DOI:10.1371/journal.pgen.0030088
[3] KEITH A HULTMAN. Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes.[J]. PLoS Genetics, 2009: e1000544. DOI:10.1371/journal.pgen.1000544
[4] KEITH A. HULTMAN  Stephen L J. Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern[J]. Developmental biology, 2010, 337 2: Pages 425-431. DOI:10.1016/j.ydbio.2009.11.019
[5] KEITH A HULTMAN S L J Alexander W Scott. Small molecule modifier screen for kit-dependent functions in zebrafish embryonic melanocytes.[J]. Zebrafish, 2008, 5 4 1: 279-287. DOI:10.1089/zeb.2008.0542

4-(4-Morpholinobutylthio)phenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(4-Morpholinobutylthio)phenol Suppliers

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57055-82-0, 4-(4-Morpholinobutylthio)phenolRelated Search:

Prostaglandin E2 ISX 9 IWP-2 24(S),25-Epoxycholesterol (not deuterated)

  • 33N14
  • 4-(4-Morpholinobutylthio)phenol
  • MoTP
  • 4-(4-morpholin-4-ylbutylsulfanyl)phenol
  • Phenol, 4-[[4-(4-morpholinyl)butyl]thio]-
  • 57055-82-0