4-(4-Morpholinobutylthio)phenol
- Product Name
- 4-(4-Morpholinobutylthio)phenol
- CAS No.
- 57055-82-0
- Chemical Name
- 4-(4-Morpholinobutylthio)phenol
- Synonyms
- MoTP;33N14;4-(4-Morpholinobutylthio)phenol;4-(4-morpholin-4-ylbutylsulfanyl)phenol;Phenol, 4-[[4-(4-morpholinyl)butyl]thio]-
- CBNumber
- CB82750473
- Molecular Formula
- C14H21NO2S
- Formula Weight
- 267.39
- MOL File
- 57055-82-0.mol
4-(4-Morpholinobutylthio)phenol Property
- storage temp.
- -20°C
- solubility
- DMSO: ≥80mg/mL
- form
- powder
- color
- white to tan
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- SML0047
- Product name
- MoTP
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $102
- Updated
- 2024/03/01
- Product number
- SML0047
- Product name
- MoTP
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $320
- Updated
- 2024/03/01
- Product number
- 15204
- Product name
- MoTP
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 15204
- Product name
- MoTP
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $86
- Updated
- 2024/03/01
- Product number
- 15204
- Product name
- MoTP
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $139
- Updated
- 2024/03/01
4-(4-Morpholinobutylthio)phenol Chemical Properties,Usage,Production
Description
MoTP (57055-82-0) specifically ablates zebrafish larval melanocytes. Melanocytotoxicity is dependent on tyrosinase activity.1,2 MoTP is a useful tool for elucidating melanocyte stem cell regeneration, recruitment and maintenance.3-5
References
1) Yang et al. (2006), Small molecule-induced ablation and subsequent regeneration of larval zebrafish melanocytes; Development, 133 3563 2) Yang et al. (2007), Mutations in gfpt1 and skiv2I2 cause distinct stage-specific defects in larval melanocyte regeneration in zebrafish; PLoS Genet., 3 e88 3) Hultman et al. (2009), Defects in ErbB-dependent establishment of adult melanocyte stem cells reveal independent origins for embryonic and regeneration melanocytes; PLoS Genet., 5 e1000544 4) Hultman et al. (2010), Differential contribution of direct-developing and stem cell-derived melanocytes to the zebrafish larval pigment pattern; Dev. Biol., 337 425 5) Hultman et al. (2008), Small molecule modifier screen for kit-dependent functions in zebrafish embryonic melanocytes; Zebrafish, 5 279
4-(4-Morpholinobutylthio)phenol Preparation Products And Raw materials
Raw materials
Preparation Products
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