N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride

Product Name: N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride
CAS No.: 864741-95-7
Chemical Name: N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride
Synonyms: SB 699551 dihydrochloride;SB 699551 dihydrochloride, 5-HT5A receptor antagonist;3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[[4-[4-[(2-phenylethylamino)methyl]phenyl]phenyl]methyl]propanamide;3-Cyclopentyl-N-(2-(dimethylamino)ethyl)-N-((4'-((phenethylamino)methyl)-[1,1'-biphenyl]-4-yl)methyl)propanamide dihydrochloride
CBNumber: CB82750695
Molecular Formula: C34H46ClN3O
Formula Weight: 548.21
MOL File: 864741-95-7.mol

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N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride Property

storage temp.: Inert atmosphere,2-8°C
solubility: H2O: soluble1mg/mL, clear (warmed)
form: powder
color: white to beige
Water Solubility: H2O: 1mg/mL, clear (warmed)

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Safety

Hazard Codes: Xn
Risk Statements: 22
Safety Statements: 46
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0853
Product name: SB 699551 dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $118
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0853
Product name: SB 699551 dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $371
Updated: 2024/03/01

Usbiological

Product number: 465915
Product name: SB 699551 Dihydrochloride
Packaging: 10mg
Price: $418
Updated: 2021/12/16

TRC

Product number: S154755
Product name: SB 699551 dihydrochloride
Packaging: 100mg
Price: $1095
Updated: 2021/12/16

ApexBio Technology

Product number: B7308
Product name: SB699551
Packaging: 50mg
Price: $1425
Updated: 2021/12/16

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N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride Chemical Properties,Usage,Production

Uses

SB 699551 Dihydrochloride is a potent 5-HT5A receptor antagonist shown to mediate hypotension in anesthetized rats (1). May also be used as an antagonist in mediating the negative effects of schizophrenia. It is also used in the role of peripheral 5-HT5A receptors in 5-HT-induced cardiac sympatho-inhibition in type 1 diabetic rats.

Biological Activity

SB 699551 dihydrochloride is also known as (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4μ-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride). It is considered as a useful tool to explain the physiological roles of the 5-ht5A receptor.', 'SB-699551 is a 5-HT5A receptor antagonist, (pKi = 8.3) with 100-fold selectivity over other 5-HT receptor populations. SB-699551 completely blocks 5-HT-induced [35S]GTPγS membrane binding in cells expressing recombinant guinea pig 5-HT-5A.

storage

Store at +4°C

N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride Suppliers

China 23 United Kingdom 1 United States 7 Global 31

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864741-95-7, N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochlorideRelated Search:

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864741-95-7