ChemicalBook > CAS DataBase List > Trifluoromethanesulfonic acid difluoromethyl ester

Trifluoromethanesulfonic acid difluoromethyl ester

Product Name
Trifluoromethanesulfonic acid difluoromethyl ester
CAS No.
1885-46-7
Chemical Name
Trifluoromethanesulfonic acid difluoromethyl ester
Synonyms
Difluoromethyl triflate;Difluoromethyl triflate 95%;Difluoromethyl trifluoromethanesulfonate;Difluoromethyl trifluoromethanesulfonate 95%;Trifluoromethanesulfonic acid difluoromethyl ester;Methanesulfonic acid, 1,1,1-trifluoro-, difluoromethyl ester
CBNumber
CB82755645
Molecular Formula
C2HF5O3S
Formula Weight
200.08
MOL File
1885-46-7.mol
More
Less

Trifluoromethanesulfonic acid difluoromethyl ester Property

Boiling point:
48.5-49 °C
Density 
1.584 g/mL at 25 °C
Flash point:
57℃
storage temp. 
2-8°C
form 
liquid
color 
Clear, colourless
More
Less

Safety

Hazard Codes 
C,Xn
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2920 3(8) / PGII
WGK Germany 
3
HS Code 
2905190098
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
792764
Product name
Difluoromethyl triflate
Purity
95%
Packaging
1ml
Price
$90.6
Updated
2024/03/01
Sigma-Aldrich
Product number
792764
Product name
Difluoromethyl triflate
Purity
95%
Packaging
5ml
Price
$642
Updated
2024/03/01
TRC
Product number
D610240
Product name
Difluoromethyltrifluoromethanesulfonate
Packaging
1g
Price
$220
Updated
2021/12/16
SynQuest Laboratories
Product number
6164-3-45
Product name
Difluoromethyl trifluoromethanesulfonate
Packaging
5G
Price
$225
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0417324
Product name
DIFLUOROMETHYL TRIFLUOROMETHANESULFONATE
Purity
95.00%
Packaging
5MG
Price
$501.07
Updated
2021/12/16
More
Less

Trifluoromethanesulfonic acid difluoromethyl ester Chemical Properties,Usage,Production

Uses

Difluoromethyl triflate (TfO-CHF2) can be used as a reagent:

  • In difluoromethylation reaction.
  • To prepare difluoromethoxylated heterocycles by reacting with hydroxylated N-based heterocycles.
  • To synthesize trifluoromethylated arenes by treating with diaryliodonium salts in the presence of copper and tetrabutylammonium difluorotriphenylsilicate (TBAT).

It allows for a simple method toward the preparation of difluoromethyl ethers and thioethers under basic conditions from alcohols and thiols. Difluoromethyl phenols can also be obtained in a single pot from boronic acids and C-H activation of arenes.

General Description

Difluoromethyl triflate (HCF2OTf) is an easy to handle, air-stable and non-ozone-depleting liquid reagent for difluoromethylation. It can be prepared by reacting trifluoromethyltrimethylsilane (TMSCF3) and triflic acid in the presence of titanium tetrachloride (TiCl4).

Trifluoromethanesulfonic acid difluoromethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Trifluoromethanesulfonic acid difluoromethyl ester Suppliers

China 49 United Kingdom 1 United States 4 Global 54
SHANG FLUORO
Tel
021-65170832 15601903708
Email
qinba_1@163.com
Country
China
ProdList
374
Advantage
60
Nanjing Ze Feng biological medicine technology Co., Ltd.
Tel
025-18851912129 18851912129
Email
1670471576@qq.com
Country
China
ProdList
843
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5806
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
0573-86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8025
Advantage
58
Aikon International Limited
Tel
025-66113011 18112977050
Fax
02557626880
Email
sales01@aikonchem.com
Country
China
ProdList
16027
Advantage
58
More
Less

View Lastest Price from Trifluoromethanesulfonic acid difluoromethyl ester manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Trifluoromethanesulfonic acid difluoromethyl ester 1885-46-7
Price
US $0.10/kg
Min. Order
0.005kg
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-15
Henan Aochuang Chemical Co.,Ltd.
Product
Trifluoromethanesulfonic acid difluoromethyl ester 1885-46-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09

1885-46-7, Trifluoromethanesulfonic acid difluoromethyl esterRelated Search:

Trifluoromethanesulfonic acid Trifluoromethanesulfonic acid tert-butyldimethylsilyl ester PHENYL TRIFLUOROACETATE TRIFLUOROACETALDEHYDE ETHYL HEMIACETAL Lithium trifluoromethanesulfonate Nickel(II) Trifluoromethanesulfonate Sodium trifluoroacetate PRASEODYMIUM (III) TRIFLUOROMETHANESULFONATE MAGNESIUM TRIFLUOROMETHANESULFONATE NEODYMIUM(III) TRIFLUOROMETHANESULFONATE Potassium trifluoroacetate GALLIUM(III) TRIFLUOROMETHANESULFONATE ERBIUM (III) TRIFLUOROMETHANESULFONATE Potassium trifluoromethanesulfonate Methyl trifluoroacetate TRIFLUOROACETALDEHYDE HYDRATE

  • Difluoromethyl trifluoromethanesulfonate 95%
  • Trifluoromethanesulfonic acid difluoromethyl ester
  • Difluoromethyl triflate 95%
  • Difluoromethyl triflate
  • Difluoromethyl trifluoromethanesulfonate
  • Methanesulfonic acid, 1,1,1-trifluoro-, difluoromethyl ester
  • 1885-46-7
  • C2HF5O3S