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Trifluoromethanesulfonic acid difluoromethyl ester

Product Name
Trifluoromethanesulfonic acid difluoromethyl ester
CAS No.
1885-46-7
Chemical Name
Trifluoromethanesulfonic acid difluoromethyl ester
Synonyms
Difluoromethyl triflate;Difluoromethyl triflate 95%;Difluoromethyl trifluoromethanesulfonate;Difluoromethyl trifluoromethanesulfonate 95%;Trifluoromethanesulfonic acid difluoromethyl ester;Methanesulfonic acid, 1,1,1-trifluoro-, difluoromethyl ester
CBNumber
CB82755645
Molecular Formula
C2HF5O3S
Formula Weight
200.08
MOL File
1885-46-7.mol
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Trifluoromethanesulfonic acid difluoromethyl ester Property

Boiling point:
48.5-49 °C
Density 
1.584 g/mL at 25 °C
Flash point:
57℃
storage temp. 
2-8°C
form 
liquid
color 
Clear, colourless
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Safety

Hazard Codes 
C,Xn
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 2920 3(8) / PGII
WGK Germany 
3
HS Code 
2905190098
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
792764
Product name
Difluoromethyl triflate
Purity
95%
Packaging
1ml
Price
$90.6
Updated
2024/03/01
Sigma-Aldrich
Product number
792764
Product name
Difluoromethyl triflate
Purity
95%
Packaging
5ml
Price
$642
Updated
2024/03/01
TRC
Product number
D610240
Product name
Difluoromethyltrifluoromethanesulfonate
Packaging
1g
Price
$220
Updated
2021/12/16
SynQuest Laboratories
Product number
6164-3-45
Product name
Difluoromethyl trifluoromethanesulfonate
Packaging
5G
Price
$225
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0417324
Product name
DIFLUOROMETHYL TRIFLUOROMETHANESULFONATE
Purity
95.00%
Packaging
5MG
Price
$501.07
Updated
2021/12/16
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Trifluoromethanesulfonic acid difluoromethyl ester Chemical Properties,Usage,Production

Uses

Difluoromethyl triflate (TfO-CHF2) can be used as a reagent:

  • In difluoromethylation reaction.
  • To prepare difluoromethoxylated heterocycles by reacting with hydroxylated N-based heterocycles.
  • To synthesize trifluoromethylated arenes by treating with diaryliodonium salts in the presence of copper and tetrabutylammonium difluorotriphenylsilicate (TBAT).

It allows for a simple method toward the preparation of difluoromethyl ethers and thioethers under basic conditions from alcohols and thiols. Difluoromethyl phenols can also be obtained in a single pot from boronic acids and C-H activation of arenes.

General Description

Difluoromethyl triflate (HCF2OTf) is an easy to handle, air-stable and non-ozone-depleting liquid reagent for difluoromethylation. It can be prepared by reacting trifluoromethyltrimethylsilane (TMSCF3) and triflic acid in the presence of titanium tetrachloride (TiCl4).

Trifluoromethanesulfonic acid difluoromethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Trifluoromethanesulfonic acid difluoromethyl ester Suppliers

China 49 United Kingdom 1 United States 4 Global 54
SHANG FLUORO
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021-65170832 15601903708
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China
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Accela ChemBio Co.,Ltd.
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400-164-7117 13681763483
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+86-21-61629029
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Sigma-Aldrich
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0371-86658258
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0371-60996044
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Jiaxing Deyi Chemical Co., Ltd.
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0573-86-0573-85866609 13325730825
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Aikon International Limited
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025-66113011 18112977050
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02557626880
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View Lastest Price from Trifluoromethanesulfonic acid difluoromethyl ester manufacturers

Zibo Hangyu Biotechnology Development Co., Ltd
Product
Trifluoromethanesulfonic acid difluoromethyl ester 1885-46-7
Price
US $0.10/kg
Min. Order
0.005kg
Purity
99.99%
Supply Ability
20 tons
Release date
2024-04-15
Henan Aochuang Chemical Co.,Ltd.
Product
Trifluoromethanesulfonic acid difluoromethyl ester 1885-46-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09

1885-46-7, Trifluoromethanesulfonic acid difluoromethyl esterRelated Search:

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  • Difluoromethyl trifluoromethanesulfonate 95%
  • Trifluoromethanesulfonic acid difluoromethyl ester
  • Difluoromethyl triflate 95%
  • Difluoromethyl triflate
  • Difluoromethyl trifluoromethanesulfonate
  • Methanesulfonic acid, 1,1,1-trifluoro-, difluoromethyl ester
  • 1885-46-7
  • C2HF5O3S