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2-AMINOTEREPHTHALIC ACID

Product Name
2-AMINOTEREPHTHALIC ACID
CAS No.
10312-55-7
Chemical Name
2-AMINOTEREPHTHALIC ACID
Synonyms
2-AMINOBENZENE-1,4-DICARBOXYLIC ACID;2,5-Dicarboxyaniline;2-AMINO-1,4-BENZENEDICARBOXYLIC ACID;DK7275;DK7418;H2ABDC;JACS-10312-55-7;2-AminoterephthaL;TIMTEC-BB SBB006751;2-AMINOTEREPHTHALATE
CBNumber
CB8275813
Molecular Formula
C8H7NO4
Formula Weight
181.15
MOL File
10312-55-7.mol
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2-AMINOTEREPHTHALIC ACID Property

Melting point:
324 °C (dec.) (lit.)
Boiling point:
314.24°C (rough estimate)
Density 
1.4283 (rough estimate)
refractive index 
1.5468 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
form 
Granular Powder
pka
3.95±0.10(Predicted)
color 
Yellow
Water Solubility 
Slightly soluble in water.
BRN 
2805625
InChI
InChI=1S/C8H7NO4/c9-6-3-4(7(10)11)1-2-5(6)8(12)13/h1-3H,9H2,(H,10,11)(H,12,13)
InChIKey
GPNNOCMCNFXRAO-UHFFFAOYSA-N
SMILES
C1(C(O)=O)=CC=C(C(O)=O)C=C1N
CAS DataBase Reference
10312-55-7(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
381071
Product name
2-Aminoterephthalic acid
Purity
99%
Packaging
25g
Price
$124
Updated
2025/07/31
TCI Chemical
Product number
A1291
Product name
2-Aminoterephthalic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$89
Updated
2025/07/31
TRC
Product number
A633293
Product name
2-Aminoterephthalic acid
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
A633293
Product name
2-Aminoterephthalic acid
Packaging
500mg
Price
$75
Updated
2021/12/16
Oakwood
Product number
227640
Product name
Aminoterephthalic acid
Packaging
25g
Price
$49
Updated
2021/12/16
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2-AMINOTEREPHTHALIC ACID Chemical Properties,Usage,Production

Chemical Properties

slight yellow crystalline powder

Uses

2-Aminoterephthalic acid is used as a pharmaceutical intermediate.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

610-29-7

10312-55-7

General procedure for the synthesis of 2-aminoterephthalic acid from 2-nitroterephthalic acid: in typical experiments, a mixture of nitroaromatic compounds (1.0 mmol), ammonium formate (3.3 mmol, 208 mg, 1.1 eq.), palladium catalyst (10% Pd/C, 2 mol%, 21 mg), and silicon dioxide (175 mg) was ball-milled in the presence of anhydrous methanol (η= 0.25 μL/mg) was ball-milled for 90 min in the presence of anhydrous methanol (η= 0.25 μL/mg). Upon completion of the milling, a small amount (~1 mg) of the crude reaction mixture was suspended in methanol and analyzed by thin-layer chromatography (TLC, usually using a solvent mixture of dichloromethane: methanol = 20:1 as eluent). The crude product was placed in a well-ventilated fume hood overnight, then suspended in methanol and filtered through a Büchner funnel. The filtrate is evaporated to give the target product 2-aminoterephthalic acid. If necessary, the final product can be further purified by column chromatography.

References

[1] Journal of Organic Chemistry, 1988, vol. 53, # 18, p. 4209 - 4218
[2] Molecules, 2018, vol. 23, # 12,
[3] Farmaco, Edizione Scientifica, 1984, vol. 39, # 11, p. 968 - 978
[4] Patent: CN103664684, 2016, B. Location in patent: Paragraph 0039
[5] Chemische Berichte, 1877, vol. 10, p. 145

2-AMINOTEREPHTHALIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINOTEREPHTHALIC ACID Suppliers

Changzhou Chemscaler Pharmtech Co., Ltd.
Tel
0519-81096292 15312577869
Email
chemscaler@yahoo.com.cn
Country
China
ProdList
311
Advantage
60
Suzhou Runsen Pharmaceutical Technology Co., Ltd.
Tel
0512-65885589 18751140360
Fax
0512-65885589
Email
sales@rosen-chemicals.com
Country
China
ProdList
292
Advantage
58
Zhongke Pingsheng (Dalian) New Materials Co., Ltd.
Tel
18841123239 13840910170;
Email
1798136513@qq.com
Country
China
ProdList
121
Advantage
58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Ark Pharm, Inc.
Tel
847-367-3680
Fax
847-367-3681
Email
sales@arkpharminc.com
Country
United States
ProdList
1670
Advantage
56
Beijing HwrkChemical Technology Co., Ltd
Tel
18515581800 18501085097
Fax
010-89508210
Email
sales.bj@hwrkchemical.com
Country
China
ProdList
9400
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
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View Lastest Price from 2-AMINOTEREPHTHALIC ACID manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-AMINOTEREPHTHALIC ACID 10312-55-7
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-12-03
Hebei Chuanghai Biotechnology Co., Ltd
Product
2-AMINOTEREPHTHALIC ACID 10312-55-7
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-22
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-AMINOTEREPHTHALIC ACID 10312-55-7
Price
US $35.60/KG
Min. Order
1KG
Purity
98%
Supply Ability
5000kg
Release date
2024-08-21

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