2-AMINOTEREPHTHALIC ACID
- Product Name
- 2-AMINOTEREPHTHALIC ACID
- CAS No.
- 10312-55-7
- Chemical Name
- 2-AMINOTEREPHTHALIC ACID
- Synonyms
- 2-AMINOBENZENE-1,4-DICARBOXYLIC ACID;2,5-Dicarboxyaniline;2-AMINO-1,4-BENZENEDICARBOXYLIC ACID;DK7275;DK7418;H2ABDC;JACS-10312-55-7;2-AminoterephthaL;TIMTEC-BB SBB006751;2-AMINOTEREPHTHALATE
- CBNumber
- CB8275813
- Molecular Formula
- C8H7NO4
- Formula Weight
- 181.15
- MOL File
- 10312-55-7.mol
2-AMINOTEREPHTHALIC ACID Property
- Melting point:
- 324 °C (dec.) (lit.)
- Boiling point:
- 314.24°C (rough estimate)
- Density
- 1.4283 (rough estimate)
- refractive index
- 1.5468 (estimate)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Granular Powder
- pka
- 3.95±0.10(Predicted)
- color
- Yellow
- Water Solubility
- Slightly soluble in water.
- BRN
- 2805625
- InChI
- InChI=1S/C8H7NO4/c9-6-3-4(7(10)11)1-2-5(6)8(12)13/h1-3H,9H2,(H,10,11)(H,12,13)
- InChIKey
- GPNNOCMCNFXRAO-UHFFFAOYSA-N
- SMILES
- C1(C(O)=O)=CC=C(C(O)=O)C=C1N
- CAS DataBase Reference
- 10312-55-7(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 381071
- Product name
- 2-Aminoterephthalic acid
- Purity
- 99%
- Packaging
- 25g
- Price
- $124
- Updated
- 2025/07/31
- Product number
- A1291
- Product name
- 2-Aminoterephthalic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $89
- Updated
- 2025/07/31
- Product number
- A633293
- Product name
- 2-Aminoterephthalic acid
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- A633293
- Product name
- 2-Aminoterephthalic acid
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- 227640
- Product name
- Aminoterephthalic acid
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
2-AMINOTEREPHTHALIC ACID Chemical Properties,Usage,Production
Chemical Properties
slight yellow crystalline powder
Uses
2-Aminoterephthalic acid is used as a pharmaceutical intermediate.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
610-29-7
10312-55-7
General procedure for the synthesis of 2-aminoterephthalic acid from 2-nitroterephthalic acid: in typical experiments, a mixture of nitroaromatic compounds (1.0 mmol), ammonium formate (3.3 mmol, 208 mg, 1.1 eq.), palladium catalyst (10% Pd/C, 2 mol%, 21 mg), and silicon dioxide (175 mg) was ball-milled in the presence of anhydrous methanol (η= 0.25 μL/mg) was ball-milled for 90 min in the presence of anhydrous methanol (η= 0.25 μL/mg). Upon completion of the milling, a small amount (~1 mg) of the crude reaction mixture was suspended in methanol and analyzed by thin-layer chromatography (TLC, usually using a solvent mixture of dichloromethane: methanol = 20:1 as eluent). The crude product was placed in a well-ventilated fume hood overnight, then suspended in methanol and filtered through a Büchner funnel. The filtrate is evaporated to give the target product 2-aminoterephthalic acid. If necessary, the final product can be further purified by column chromatography.
References
[1] Journal of Organic Chemistry, 1988, vol. 53, # 18, p. 4209 - 4218
[2] Molecules, 2018, vol. 23, # 12,
[3] Farmaco, Edizione Scientifica, 1984, vol. 39, # 11, p. 968 - 978
[4] Patent: CN103664684, 2016, B. Location in patent: Paragraph 0039
[5] Chemische Berichte, 1877, vol. 10, p. 145
2-AMINOTEREPHTHALIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINOTEREPHTHALIC ACID Suppliers
- Tel
- --
- Fax
- --
- box@unichemcorporation.com
- Country
- France
- ProdList
- 171
- Advantage
- 50
View Lastest Price from 2-AMINOTEREPHTHALIC ACID manufacturers
- Product
- 2-AMINOTEREPHTHALIC ACID 10312-55-7
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-12-03
- Product
- 2-AMINOTEREPHTHALIC ACID 10312-55-7
- Price
- US $10.00/KG
- Min. Order
- 100KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-11-22
- Product
- 2-AMINOTEREPHTHALIC ACID 10312-55-7
- Price
- US $35.60/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 5000kg
- Release date
- 2024-08-21