ChemicalBook > CAS DataBase List > 2-AMINOTEREPHTHALIC ACID

2-AMINOTEREPHTHALIC ACID

Product Name: 2-AMINOTEREPHTHALIC ACID
CAS No.: 10312-55-7
Chemical Name: 2-AMINOTEREPHTHALIC ACID
Synonyms: 2-AMINOBENZENE-1,4-DICARBOXYLIC ACID;2,5-Dicarboxyaniline;2-AMINO-1,4-BENZENEDICARBOXYLIC ACID;DK7275;DK7418;H2ABDC;JACS-10312-55-7;2-AminoterephthaL;TIMTEC-BB SBB006751;2-AMINOTEREPHTHALATE
CBNumber: CB8275813
Molecular Formula: C8H7NO4
Formula Weight: 181.15
MOL File: 10312-55-7.mol

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2-AMINOTEREPHTHALIC ACID Property

Melting point:: 324 °C (dec.) (lit.)
Boiling point:: 314.24°C (rough estimate)
Density: 1.4283 (rough estimate)
refractive index: 1.5468 (estimate)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: Granular Powder
pka: 3.95±0.10(Predicted)
color: Yellow
Water Solubility: Slightly soluble in water.
BRN: 2805625
InChI: InChI=1S/C8H7NO4/c9-6-3-4(7(10)11)1-2-5(6)8(12)13/h1-3H,9H2,(H,10,11)(H,12,13)
InChIKey: GPNNOCMCNFXRAO-UHFFFAOYSA-N
SMILES: C1(C(O)=O)=CC=C(C(O)=O)C=C1N
CAS DataBase Reference: 10312-55-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 29224999

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 381071
Product name: 2-Aminoterephthalic acid
Purity: 99%
Packaging: 25g
Price: $124
Updated: 2025/07/31

TCI Chemical

Product number: A1291
Product name: 2-Aminoterephthalic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 25g
Price: $89
Updated: 2025/07/31

TRC

Product number: A633293
Product name: 2-Aminoterephthalic acid
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: A633293
Product name: 2-Aminoterephthalic acid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Oakwood

Product number: 227640
Product name: Aminoterephthalic acid
Packaging: 1g
Price: $10
Updated: 2021/12/16

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2-AMINOTEREPHTHALIC ACID Chemical Properties,Usage,Production

Chemical Properties

slight yellow crystalline powder

Uses

2-Aminoterephthalic acid is used as a pharmaceutical intermediate.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

610-29-7

10312-55-7

General procedure for the synthesis of 2-aminoterephthalic acid from 2-nitroterephthalic acid: in typical experiments, a mixture of nitroaromatic compounds (1.0 mmol), ammonium formate (3.3 mmol, 208 mg, 1.1 eq.), palladium catalyst (10% Pd/C, 2 mol%, 21 mg), and silicon dioxide (175 mg) was ball-milled in the presence of anhydrous methanol (η= 0.25 μL/mg) was ball-milled for 90 min in the presence of anhydrous methanol (η= 0.25 μL/mg). Upon completion of the milling, a small amount (~1 mg) of the crude reaction mixture was suspended in methanol and analyzed by thin-layer chromatography (TLC, usually using a solvent mixture of dichloromethane: methanol = 20:1 as eluent). The crude product was placed in a well-ventilated fume hood overnight, then suspended in methanol and filtered through a Büchner funnel. The filtrate is evaporated to give the target product 2-aminoterephthalic acid. If necessary, the final product can be further purified by column chromatography.

References

[1] Journal of Organic Chemistry, 1988, vol. 53, # 18, p. 4209 - 4218
[2] Molecules, 2018, vol. 23, # 12,
[3] Farmaco, Edizione Scientifica, 1984, vol. 39, # 11, p. 968 - 978
[4] Patent: CN103664684, 2016, B. Location in patent: Paragraph 0039
[5] Chemische Berichte, 1877, vol. 10, p. 145

2-AMINOTEREPHTHALIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-AMINOTEREPHTHALIC ACID manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 2-AMINOTEREPHTHALIC ACID 10312-55-7
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000KGS
Release date: 2025-12-03

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-AMINOTEREPHTHALIC ACID 10312-55-7
Price: US $10.00/KG
Min. Order: 100KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-22

Hebei Chuanghai Biotechnology Co,.LTD

Product: 2-AMINOTEREPHTHALIC ACID 10312-55-7
Price: US $35.60/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 5000kg
Release date: 2024-08-21

10312-55-7, 2-AMINOTEREPHTHALIC ACIDRelated Search:

Zinc acetate dihydrate Nitroterephthalic acid 2,5-DIANILINOTEREPHTHALIC ACID Dimethyl nitroterephthalate 1-METHYL 2-NITROTEREPHTHALATE 2-AMINOTEREPHTHALIC ACID AMINOTEREPHTHALIC ACID DIMETHYL ESTER 2-AMINOTEREPHTHALIC ACID METHYL ESTER,2-AMINOTEREPHTHALIC ACID 1-METHYL ESTER,2-AMINOTEREPHTHALIC ACID MONOMETHYL ESTER 2,5-DIAMINOTEREPHTHALIC ACID AKOS B007547 2-AMINO-5-CHLORO-1,4-BENZENEDICARBOXYLIC ACID 4-CARBOXYLIC-ISATOIC ANHYDRIDE AURORA 11276 DIMETHYL 2-[(PHENOXYCARBONYL)AMINO]TEREPHTHALATE AURORA 7335 AURORA 5222 AURORA 5472 2,5-BIS(2-HYDROXYETHYLAMINO)TEREPHTHALIC ACID

2-AMINOTEREPHTHALIC ACID

2-AMINOBENZENE-1,4-DICARBOXYLIC ACID

2-AMINO-1,4-BENZENEDICARBOXYLIC ACID

TIMTEC-BB SBB006751

2-Aminoterephthalic acid, 99+%

JACS-10312-55-7

2-AMINOTEREPHTHALATE

Aminoterephthalicacid

2-Aminobenzene-1,4-dicarboxylic acid, 2,5-Dicarboxyaniline

2-AMinoterephthalic acid, 99+% 25GR

2-AMinoterephthalic acid, vzorka

2-AMinoterephthalic acid 99%

2-Aminophthalic acid

2-AminoterephthaL

2-Aminoterephthalic Acid &gt

2-Aminoterephthalic Acid,>98%

1,4-Benzenedicarboxylic acid, 2-amino-

Dimethyl 5-bromo terephthalate

2-AMINOTEREPHTHALIC ACID USP/EP/BP

2,5-Dicarboxyaniline

DK7275

DK7418

2-Aminoterephthalic acid (2-ATA)

3-aminoterephthalic acid

2,4-2-AMINOTEREPHTHALIC ACID

(2-Bromo-5-methoxy-9-methyl-phenyl)-methano

H2ABDC

10312-55-7

H2NC6H314CO2H2

Unnatural Amino Acid Derivatives

Specialty Synthesis

Peptide Synthesis

Aromatic Amino Acids

Peptide Synthesis

Unnatural Amino Acid Derivatives

Phthalic Acids, Esters and Derivatives

Derivatives of phthalic acid

10312-55-7