D-Luciferin

Product Name: D-Luciferin
CAS No.: 2591-17-5
Chemical Name: D-Luciferin
Synonyms: uciferin;LUCIFERIN;D-LUCIFERIN;D-Leciferin;LUCIFERIN, D-;D(-)-LUCIFERIN;AURORA KA-6717;BEETLE LUCIFERIN;FIREFLY LUCIFERIN;Photinus luciferin
CBNumber: CB8283216
Molecular Formula: C11H8N2O3S2
Formula Weight: 280.32
MOL File: 2591-17-5.mol

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D-Luciferin Property

Melting point:: 200-204 °C
alpha: D22 -36° (c = 1.2 in DMF)
Boiling point:: 587.6±60.0 °C(Predicted)
Density: 1.4916 (rough estimate)
refractive index: 1.5650 (estimate)
storage temp.: -20°C
solubility: DMF:30.0(Max Conc. mg/mL);107.02(Max Conc. mM)
DMSO:35.33(Max Conc. mg/mL);126.05(Max Conc. mM)
pka: 8.31±0.40(Predicted)
form: Powder
color: Off-white to light yellow
λmax: 360nm(H2O)(lit.)
Merck: 14,4086
BRN: 30484
InChI: InChI=1S/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,14H,4H2,(H,15,16)/t7-/m1/s1
InChIKey: BJGNCJDXODQBOB-SSDOTTSWSA-N
SMILES: S1C[C@H](C(O)=O)N=C1C1=NC2=CC=C(O)C=C2S1

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36/37/39-24/25
WGK Germany: 3
F: 8-10
HS Code: 29342000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: L6152
Product name: D-Luciferin
Purity: synthetic, BioXtra, ≥99% (HPLC)
Packaging: 1mg
Price: $279
Updated: 2024/03/01

Sigma-Aldrich

Product number: L6152
Product name: D-Luciferin
Purity: synthetic, BioXtra, ≥99% (HPLC)
Packaging: 10mg
Price: $1380
Updated: 2024/03/01

TCI Chemical

Product number: A5030
Product name: D-(-)-Luciferin [Chemiluminescence Reagent]
Purity: >98.0%(HPLC)
Packaging: 10mg
Price: $204
Updated: 2024/03/01

TCI Chemical

Product number: A5030
Product name: D-(-)-Luciferin [Chemiluminescence Reagent]
Purity: >98.0%(HPLC)
Packaging: 50mg
Price: $622
Updated: 2024/03/01

Cayman Chemical

Product number: 25836
Product name: D-Luciferin
Purity: ≥98%
Packaging: 10mg
Price: $37
Updated: 2024/03/01

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D-Luciferin Chemical Properties,Usage,Production

Description

D-Luciferin is a popular bioluminescent substrate of luciferase in the presence of ATP, used in luciferase-based bioluminescence imaging and cell-based high-throughput screening applications. In an immunocompetent mouse model of ovarian cancer, the use of D-luciferin substrate and firefly luciferase preserves tumour-host immune interactions since bioluminescent imaging is a more sensitive indication of tumour growth than weight gain.

Chemical Properties

off-white to light yellow powder

Uses

D-Luciferin has been used in determining luciferase activity by luciferase assay in mice and Arabidopsis thaliana seeds. It has also been used in measuring bioluminescence in neonatal rat ventricular cardiomyocytes.

Uses

D-Luciferin has been used in the preparation of the reaction mixture for nitric oxide determination by minescence measurement. It has also been used in the preparation of D-luciferin stock solution for luciferin assays.

Uses

In the assay of ATP.

Definition

ChEBI: A 1,3-thiazolemonocarboxylic acid consisting of 3,5-dihydrothiophene-4-carboxylic acid having a 6-hydroxybenzothiazol-2-yl group at the 2-position.

General Description

D-Luciferin is a small molecule present abundantly in bioluminescent organisms. This molecule is sensitive to oxygen and light.

Biochem/physiol Actions

D-Luciferin uptake within the cells is regulated by the adenosine triphosphate (ATP)-binding cassette (ABC) transporter inhibitors like ATP-binding cassette transporter G2 (ABCG2)/ breast cancer resistance protein (BCRP) inhibitor fumitremorgin C. This substrate is oxidized by firefly luciferase that results in emitting a photon, which has the capability of passing through living tissues.

Purification Methods

D-Luciferin crystallises as pale yellow needles from H2O, or MeOH (83mg/7mL). It has UV max at 263 and 327nm (log 3.88 and 4.27) in 95% EtOH. The Na salt has a solubility of 4mg in 1 mL of 0.05M glycine. [White et al. J Am Chem Soc 83 2402 1961, 85 337 1963, UV and IR: Bitler & McElroy Arch Biochem 72 358 1957, Review: Cormier et al. Fortschr Chem Org Naturst 30 1 1973, Beilstein 27 III/IV 8934.]

D-Luciferin Preparation Products And Raw materials

Raw materials

Preparation Products

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D-Luciferin Suppliers

Americas 1 Belgium 1 China 248 Estonia 2 Europe 2 France 2 Germany 14 India 10 Japan 1 Poland 1 Russia 1 South Korea 1 Switzerland 4 The Netherlands 1 United Kingdom 18 United States 43 Global 350

Acros Organics

Tel: --
Fax: --
Email: info@acros.com
Country: Belgium
ProdList: 6772
Advantage: 81

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View Lastest Price from D-Luciferin manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: D-luciferin 2591-17-5
Price: US $0.00/G
Min. Order: 10G
Purity: 98%min
Supply Ability: 30kg/month
Release date: 2023-02-15

Hebei Mojin Biotechnology Co., Ltd

Product: D-Luciferin 2591-17-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99.2%
Supply Ability: 50000KG/month
Release date: 2024-10-22

Career Henan Chemical Co

Product: D-LUCIFERIN 2591-17-5
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-21

2591-17-5, D-LuciferinRelated Search:

D-Luciferin Coelenterazine LUCIFERIN, D-,LUCIFERIN,FIREFLY LUCIFERIN,FIREFLY LUCIFERIN,LUCIFERIN, D-,LUCIFERIN D-LUCIFERIN, ETHYL ESTER D-Luciferin potassium salt D-Luciferin sodium salt L-LUCIFERIN,L-Luciferin free acid, 99%,L-Luciferin free acid, 99%,L-LUCIFERIN LUCIFERASE 6-Benzothiazolol(7CI,8CI,9CI) D-luciferin 6-O-phosphate sodium,D-LUCIFERIN 6'-O-PHOSPHATE TRISODIUM &,D-LUCIFERIN 6'-O-PHOSPHATE TRISODIUM &,D-luciferin 6-O-phosphate sodium LUCIFERIN 6'-METHYL ETHER SODIUM SALT,luciferin 6'-methyl ether sodium,LUCIFERIN 6'-METHYL ETHER SODIUM SALT,luciferin 6'-methyl ether sodium 6-AMINO-D-LUCIFERIN,6-AMINO LUCIFERIN,6-AMINO-D-LUCIFERIN,6-AMINO LUCIFERIN D-LUCIFERIN-6-O-BETA-D-GALACTOPYRANOSIDE LUCIFERIN (RENILLA),LUCIFERIN (RENILLA) Cypridinia, Vargula Luciferin dihydrobromide,Cypridinia, Vargula Luciferin dihydrobromide,VARGULA LUCIFERIN DIHYDROBROMIDE,VARGULA LUCIFERIN DIHYDROBROMIDE L-LUCIFERIN, POTASSIUM SALT,L-LUCIFERIN, POTASSIUM SALT LUCIFERIN (WATASENIA),LUCIFERIN (WATASENIA) DMNPE-CAGED LUCIFERIN,DMNPE-CAGED LUCIFERIN

4,5-DIHYDRO-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-4-THIAZOLECARBOXY

4,5-DIHYDRO-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-4-THIAZOLE-CARBOXYLIC ACID

4,5-DIHYDRO-(6-HYDROXY-2-BENZOTHIAZOYL)-4-THIAZOLE CARBOXYLIC ACID

LUCIFERIN, D-

LUCIFERIN

D(-)-2-(6'-HYDROXY-BENZOTHIAZOLYL)-DELTA2-THIAZOLINE-4-CARBOXYLIC ACID

D(-)-LUCIFERIN

D-LUCIFERIN

D-LUCIFERIN FIREFLY

D-Luciferin≥ 99% (HPLC)

Photinus luciferin

D-Luciferin, free acid *CAS#: 2591-17-5*

(S)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4 thiazolecarboxylic acid

(4S)-2-(6-Hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid

Luciferin, D- - Firefly Luciferin

2-(6-oxo-1,3-benzothiazol-2-ylidene)-4-thiazolidinecarboxylic acid

FIREFLY LUCIFERIN

BEETLE LUCIFERIN

AURORA KA-6717

(S)-2-[6-HYDROXY-2-BENZOTHIAZOLYL]-2-THIAZOLENE-4

(S)-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-2-THIAZOLINE-4-CARBOXYLIC ACID

(S)-4,5-dihydro-2-(6-hydroxybenzothiazol-2-yl)thiazole-4-carboxylic acid

D-Luciferin free acid, 99%

D-LUCIFERIN SYNTHETIC

D-LUCIFERIN SIGMAULTRA

D -LUCIFERIN SYNTHETIC CRYSTALLINE

Beetle luciferin Firefly luciferin

D-LUCIFERIN,FREEACID,ULTRAPURE

D-Leciferin

(4S)-2-(6-hydroxy-1,3-benzothiazol-2-yl)-4,5-dihydro-1,3-thiazole-4-carboxylic acid

D-(-)-Luciferin&nbsp

(D)-4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid, Firefly (synthetic), 99%

D-LUCIFERINFREEACID,99%

D-Luciferin, Free acid >99.5%

2-(6-Hydroxy-benzothiazol-2-yl)-thiazole-4-carboxylic acid D-Luciferin

Firefly Luciferin, (S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4-carboxylic acid, 4,5-Dihydro-2-(6-hydroxy-2-benzothiazolyl)-4-thiazolecarboxylic acid

(4S)-2-(6-Hydroxy-2-benzothiazolyl)-2-thiazoline-4β-carboxylic acid

(4S)-2-(6-Hydroxybenzothiazole-2-yl)-2-thiazoline-4-carboxylic acid

D-(-)-Luciferin [Chemiluminescence Reagent]

(4S)-4,5-Dihydro-(6-hydroxy-2-benzothiazoyl)-4-thiazolecarboxylic acid

(S)-2-(6-hydroxybenzo[d]thiazol-2-yl)-4,5-dihydrothiazole-4-carboxylic acid

D-(-)-Luciferin [Chemiluminescence Reagent]&gt

uciferin

4-Thiazolecarboxylic acid, 4,5-dihydro-2-(6-hydroxy-2-benzothiazolyl)-, (4S)-

D-luciferin (Firefly luciferin)

D-Luciferin ex. Firefly, 99%

7-Dihydroxyflavone

D-Luciferin Firefly, Free Acid

2591-17-5

2951-17-5

C11H7FN2O3S2

Biochemicals and Reagents

Analytical Enzymes

BioChemical

Enzymes, Inhibitors, and Substrates

Detection

Fluorescent Probes, Labels, Particles and Stains

Luciferase