3-HYDROXYANTHRANILIC ACID
- Product Name
- 3-HYDROXYANTHRANILIC ACID
- CAS No.
- 548-93-6
- Chemical Name
- 3-HYDROXYANTHRANILIC ACID
- Synonyms
- 2-AMINO-3-HYDROXYBENZOIC ACID;3-HYDROXY-ANTHRANILATE;3-HYDROXYANTHRANILLIC ACID;3-Ohaa;NSC 522891;JACS-548-93-6;3-oxyanthranilicacid;3-Oxyanthranilic acid;Mesalazine Impurity 41;3-HYDROXYANTHRANILIC ACID
- CBNumber
- CB8291725
- Molecular Formula
- C7H7NO3
- Formula Weight
- 153.14
- MOL File
- 548-93-6.mol
3-HYDROXYANTHRANILIC ACID Property
- Melting point:
- 240 °C (dec.)(lit.)
- Boiling point:
- 276.03°C (rough estimate)
- Density
- 1.3585 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly, Heated)
- form
- Liquid or Low Melting Solid
- pka
- pK1: 2.5(+1);pK2: 5.192(0);pK3: 10.118(OH) (25°C)
- color
- Clear colorless to white to yellow to orange
- InChI
- InChI=1S/C7H7NO3/c8-6-4(7(10)11)2-1-3-5(6)9/h1-3,9H,8H2,(H,10,11)
- InChIKey
- WJXSWCUQABXPFS-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=CC(O)=C1N
- CAS DataBase Reference
- 548-93-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-36/37/38-40
- Safety Statements
- 22-26-36
- WGK Germany
- 3
- RTECS
- DG2625000
- HS Code
- 29225000
- Hazardous Substances Data
- 548-93-6(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- 148776
- Product name
- 3-Hydroxyanthranilic acid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $341
- Updated
- 2025/07/31
- Product number
- 148776
- Product name
- 3-Hydroxyanthranilic acid
- Purity
- 97%
- Packaging
- 1g
- Price
- $1300
- Updated
- 2025/07/31
- Product number
- A0316
- Product name
- 3-Hydroxyanthranilic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $135
- Updated
- 2025/07/31
- Product number
- A0316
- Product name
- 3-Hydroxyanthranilic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $541
- Updated
- 2025/07/31
- Product number
- 20512
- Product name
- 3-hydroxy Anthranilic Acid
- Purity
- ≥98%
- Packaging
- 250mg
- Price
- $44
- Updated
- 2024/03/01
3-HYDROXYANTHRANILIC ACID Chemical Properties,Usage,Production
Uses
3-Hydroxyanthranilic Acid is one of the tryptophan’s metabolites along the kynurenine pathway. 3-Hydroxyanthranilic Acid has been shown to induce apoptosis in T cells.
Definition
ChEBI: An aminobenzoic acid that is benzoic acid substituted at C-2 by an amine group and at C-3 by a hydroxy group. It is an intermediate in the metabolism of the amino acid tryptophan.
reaction suitability
reaction type: solution phase peptide synthesis
in vivo
3-hydroxyanthranilic acid (40 μg/each mouse, injected intracerebrally into the forebrains) can induce HO-1 in 8-week-old C57BL6 mice[4].
3-hydroxyanthranilic acid (200 mg/kg, i.p., three times a week, 8 weeks) lowers plasma lipids and decreases atherosclerosis in hypercholesterolaemic mice[5].
3-hydroxyanthranilic acid (200 mg/kg, i.p., 6 weeks) contributes to angiotensin II–induced abdominal aortic aneurysm formation in mice[7].
3-hydroxyanthranilic acid (120 mg/kg, tail vein injection, once weekly, 12 weeks) combines with Butyricicoccus pullicaecorum to prevent postmenopausal osteoporosis in rats by modulating gut microbiota and Th17/Treg[8].
IC 50
Human Endogenous Metabolite
Purification Methods
The hydrochloride has m 227o (from dilute HCl). [Beilstein 14 H 587, 14 III 1463, 14 IV 2071.] Possible carcinogen.
3-HYDROXYANTHRANILIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 3-HYDROXYANTHRANILIC ACID manufacturers
- Product
- 3-HYDROXYANTHRANILIC ACID 548-93-6
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 99
- Supply Ability
- 100kg
- Release date
- 2020-01-07