ChemicalBook > CAS DataBase List > 3-Amino-3-(4-methylphenyl)propionic acid

3-Amino-3-(4-methylphenyl)propionic acid

Product Name
3-Amino-3-(4-methylphenyl)propionic acid
CAS No.
68208-18-4
Chemical Name
3-Amino-3-(4-methylphenyl)propionic acid
Synonyms
RARECHEM AK HC T309;3-Amino-3-(4-methyL;DL--(p-Methylphenyl)alanine;DL-BETA-(P-METHYLPHENYL)ALANINE;3-Amino-3-(p-tolyl)propanoicacid;3-AMINO-3-(P-TOLYL)PROPIONIC ACID;3-AMINO-3-(4-TOLYL)PROPIONIC ACID;(S)-3-(1-aminopropyl)benzoic acid;3-(P-METHYLPHENYL)-DL-BETA-ALANINE;DL-3-Amino-3-p-tolyl-propionic acid
CBNumber
CB8292090
Molecular Formula
C10H13NO2
Formula Weight
179.22
MOL File
68208-18-4.mol
More
Less

3-Amino-3-(4-methylphenyl)propionic acid Property

Melting point:
219 °C (dec.)(lit.)
Boiling point:
311.75°C (rough estimate)
Density 
1.1248 (rough estimate)
refractive index 
1.4989 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
3.71±0.10(Predicted)
Appearance
White to off-white Solid
CAS DataBase Reference
68208-18-4(CAS DataBase Reference)
More
Less

Safety

Safety Statements 
24/25
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29224999
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
A2345
Product name
3-Amino-3-(p-tolyl)propionic Acid
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$68
Updated
2025/07/31
TCI Chemical
Product number
A2345
Product name
3-Amino-3-(p-tolyl)propionic Acid
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$342
Updated
2025/07/31
TRC
Product number
A614628
Product name
3-Amino-3-(4-methylphenyl)propanoicAcid
Packaging
50mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA118211
Product name
3-Amino-3-(4-methylphenyl)propanoic acid
Packaging
250mg
Price
$57.5
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA118211
Product name
3-Amino-3-(4-methylphenyl)propanoic acid
Packaging
500mg
Price
$100
Updated
2021/12/16
More
Less

3-Amino-3-(4-methylphenyl)propionic acid Chemical Properties,Usage,Production

Chemical Properties

white to off-white granular or crystalline powder

Synthesis

141-82-2

104-87-0

68208-18-4

To a 250 mL round bottom flask was added 50.0 g (0.42 mol) of p-toluylaldehyde, 47.6 g (0.46 mol) of malonic acid and 64.2 g (0.83 mol) of ammonium acetate dissolved in ethanol. The reaction mixture was heated to 80-90°C under stirring and refluxed for 7.5 hours. Upon completion of the reaction, the mixture was cooled to 0-5°C and stirred for 30 min, followed by filtration to afford 51.4 g of 3-amino-3-(p-tolyl)propionic acid (racemic mixture) as a white powder (68.9% isolated yield based on p-toluylaldehyde). The physical properties of 3-amino-3-(p-tolyl)propionic acid (racemic mixture) are as follows: 1H-NMR (δ, ppm, D2O + DCl): 2.30 (s, 3H), 3.04 (dd, 1H, J = 17.1, 6.8 Hz), 3.20 (dd, 1H, J = 17.1, 7.3 Hz), 4.74 (dd, 1H, J = 7.3, 6.8 Hz), 7.29 (d, 2H, J = 8.3 Hz), 7.36 (d, 2H, J = 8.3 Hz). 13C-NMR (δ, ppm, D2O + DCl): 23.4, 40.7, 54.4, 130.0, 133.0, 135.0, 143.1, 176.3. MS (EI) m/z: 179 (M+). MS (CI, i-C4H10) m/z: 180 (MH+). Elemental analysis: Calculated C, 67.02%; H, 7.31%; N, 7.82%. Measured values C, 67.05%; H, 7.40%; N, 7.66%.

References

[1] Patent: EP1621529, 2006, A1. Location in patent: Page/Page column 27-28
[2] European Journal of Medicinal Chemistry, 2018, vol. 156, p. 252 - 268
[3] Advanced Synthesis and Catalysis, 2010, vol. 352, # 2-3, p. 395 - 406
[4] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 11, p. 1207 - 1212
[5] Bulletin de la Societe Chimique de France, 1987, # 6, p. 1079 - 1083

3-Amino-3-(4-methylphenyl)propionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

3-Amino-3-(4-methylphenyl)propionic acid Suppliers

Americas 1 Belgium 1 China 90 Europe 1 Germany 3 India 2 Japan 2 Switzerland 1 Ukraine 1 United Kingdom 6 United States 20 Global 128
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Shanghai HC Biotech Co., Ltd
Tel
021-20227858
Fax
+86-21-20227857
Email
sale@hcbiotech.com.cn
Country
China
ProdList
1095
Advantage
55
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14101
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11705
Advantage
57
Sinopharm Chemical Reagent Co,Ltd.
Tel
86-21-63210123
Fax
86-21-63290778 86-21-63218885
Email
sj_scrc@sinopharm.com
Country
China
ProdList
9815
Advantage
79
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Runpharm Technology Limited
Tel
18171398856 2968382473
Fax
0086-21-50758330
Email
service@runpharm.com
Country
China
ProdList
716
Advantage
55
Shanghai Yolne Chemical Co., Ltd.
Tel
021-62960152
Fax
021-52212593
Email
934678158@qq.com
Country
China
ProdList
9899
Advantage
55
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.
Tel
+86-28-85122536 85324413
Fax
+86-28-85326443
Email
market@astatech.cn
Country
China
ProdList
8026
Advantage
55
Amatek Scientific Co. Ltd.
Tel
0512-56316828 4008675858
Fax
+86-512-56316826
Email
sales@amateksci.com
Country
China
ProdList
9874
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Aspire Biological Technology Co., Ltd.
Tel
021-61317773
Fax
021-61486878
Email
sales@aspirebio.com
Country
China
ProdList
2880
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5219
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8144
Advantage
55
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 18626450290
Email
yftan@aikonchem.com
Country
China
ProdList
16679
Advantage
50
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10453
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Shanghai Changyan Chem & Tech Co., Ltd.
Tel
021-20242659 18930833303
Fax
+86 (21) 2024-2659
Email
Sales@changyanchem.cn
Country
China
ProdList
5001
Advantage
55
Shandong Xiya Chemical Co., Ltd.
Tel
4009903999 13395398332
Fax
0539-6365991
Email
sales@xiyashiji.com
Country
China
ProdList
20794
Advantage
60
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 18101056239
Email
3193328036@qq.com
Country
China
ProdList
29760
Advantage
68
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Shanghai CR Corporation Limited
Tel
13062833949; 4006653949 4006653949
Fax
QQ: 2136646215
Email
fred.wen@crcorporation.cn
Country
China
ProdList
9757
Advantage
58
Changzhou Changjin Pharmaceutical Technology Co., Ltd
Tel
0519-83818068 18951215668
Fax
0519-83818068
Email
sales@cjpharmtech.com
Country
China
ProdList
127
Advantage
55
Capot Chemical Co.,Ltd.
Tel
+86-（0）57185586718; +8613336195806
Fax
+86-571-85864795
Email
sales@capot.com
Country
China
ProdList
29735
Advantage
60
Bejing Famous Pharmaceutical Technology Co., Ltd.
Tel
13331045123
Fax
86-10-80339217
Email
2559355526@qq.com
Country
China
ProdList
14193
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 400821072
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25000
Advantage
58
3A Chemicals
Tel
400-668-9898
Fax
010-51582189
Email
service@3achem.com
Country
China
ProdList
20557
Advantage
58
Shanghai Yurlic Chemical S&T Co.Ltd.
Tel
021-37285141 15618858630
Fax
021-37285142
Email
yancf@yulibiotech.com
Country
China
ProdList
170
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-63315541 13323832564
Fax
QQ:3001332135
Email
3001332135@qq.com
Country
China
ProdList
9972
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52687
Advantage
58
Cool Pharm, Ltd
Tel
021-58581007 18019463053
Fax
021-50966098
Email
sales@coolpharm.com
Country
China
ProdList
12878
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
+86-0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25356
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
+86-0571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
China
ProdList
52846
Advantage
58
SIMAGCHEM CORP
Tel
+86-5922680277 +86-13806087780
Email
sale@simagchem.com
Country
China
ProdList
17346
Advantage
58
Wuhan Hongde Yuexin Pharmatech Co.,Ltd
Tel
027-83855393 15071227934
Fax
027-83855393
Email
3306264753@qq.com
Country
China
ProdList
982
Advantage
58
Binhai gill polypeptide co. LTD
Tel
021-61263389 13524856427
Fax
WeChat630417570
Email
Joetang@glschina.com
Country
China
ProdList
10000
Advantage
58
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
Tel
0513-82104991 18912868361
Fax
QQ1907456386
Email
sales11@btcpharm.com
Country
China
ProdList
1250
Advantage
58
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Email
sales@accelachem.com
Country
China
ProdList
10467
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-6139-8061 +86-86-13650506873
Email
sales@chemdad.com
Country
China
ProdList
39927
Advantage
58
CONIER CHEM AND PHARMA LIMITED
Tel
+8618523575427
Email
sales@conier.com
Country
China
ProdList
49975
Advantage
58
More
Less

View Lastest Price from 3-Amino-3-(4-methylphenyl)propionic acid manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4
Price
US $1.10-9.90/KG
Min. Order
1KG
Purity
99%min
Supply Ability
100KG
Release date
2025-08-20
Henan Aochuang Chemical Co.,Ltd.
Product
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19
Career Henan Chemical Co
Product
3-Amino-3-(4-methylphenyl)propionic acid 68208-18-4
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

68208-18-4, 3-Amino-3-(4-methylphenyl)propionic acidRelated Search:

3,4'-DIAMINODIPHENYLMETHANE Propionic anhydride 3-Amino-3-phenylpropionic acid ALTRENOGEST β-Alanine 2,2-Bis(hydroxymethyl)propionic acid (S)-(+)-2-Phenylpropionic acid Glycine Propionic acid N,N-Dimethyl-1,4-phenylenediamine 3-AMINO-3-(4-METHYLPHENYL)PROPANOIC ACID HYDROCHLORIDE Tris(hydroxymethyl)aminomethane (R)-3-(FMOC-AMINO)-3-(4-METHYLPHENYL)PROPIONIC ACID (R)-3-AMINO-3-(2-METHYL-PHENYL)-PROPIONIC ACID (S)-3-(Boc-amino)-3-(3-methylphenyl)propionic acid, Boc-3-methyl-D-β-phenylalanine (R)-3-AMINO-3-(4-METHYL-PHENYL)-PROPIONIC ACID (S)-3-(BOC-AMINO)-3-(2-METHYLPHENYL)PROPIONIC ACID Boc-(S)-3-Amino-3-(4-methylphenyl)propionic acid

  • 3-AMINO-3-(P-TOLYL)PROPIONIC ACID 98%
  • 3-Amino-3-(p-tolyl)propionic acid,98%
  • 3-AMINO-3-(4-METHYLPHENYL)PROPANOIC ACID
  • 3-AMINO-3-(4-METHYLPHENYL)PROPIONIC ACID
  • 3-AMINO-3-(P-TOLYL)PROPIONIC ACID
  • RARECHEM AK HC T309
  • Benzenepropanoic acid, .beta.-amino-4-methyl-
  • 3-Amino-3-(<i>p</i>-tolyl)propionic Acid
  • DL-3-AMINO-3-(4-METHYL-PHENYL)-PROPIONIC ACID
  • DL-BETA-(P-METHYLPHENYL)ALANINE
  • 3-AMINO-3-(4-METHYLPHENYL)PROPIONIC ACI&
  • DL--(p-Methylphenyl)alanine
  • 3-(P-METHYLPHENYL)-DL-BETA-ALANINE
  • DL-3-Amino-3-p-tolyl-propionic acid
  • 3-AMINO-3-(4-TOLYL)PROPIONIC ACID
  • (RS)-3-Amino-3-(4-methylphenyl)-propionic acid
  • 3-Amino-3-(p-tolyl)propanoicacid
  • 3-Amino-3-(p-tolyl)propionic Acid &gt
  • 3-Amino-3-(4-methyL
  • Benzenepropanoic acid, β-amino-4-methyl-
  • (S)-3-(1-aminopropyl)benzoic acid
  • 68208-18-4
  • H3CC6H4CHNH2CH2CO2H
  • Organic Building Blocks
  • Carboxylic Acids
  • Carbonyl Compounds
  • C10
  • Building Blocks
  • B-Amino
  • C10
  • Carbonyl Compounds
  • Carboxylic Acids