ChemicalBook > CAS DataBase List > 4-Chloro-2-iodophenol

4-Chloro-2-iodophenol

Product Name
4-Chloro-2-iodophenol
CAS No.
71643-66-8
Chemical Name
4-Chloro-2-iodophenol
Synonyms
2-Iodo-4-chlorophenol;4-CHLORO-2-IODOPHENOL;Phenol, 4-chloro-2-iodo-
CBNumber
CB8293653
Molecular Formula
C6H4ClIO
Formula Weight
254.45
MOL File
71643-66-8.mol
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4-Chloro-2-iodophenol Property

Melting point:
75.0 to 79.0 °C
Boiling point:
225.1±20.0 °C(Predicted)
Density 
2.087±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
powder to crystal
pka
8.07±0.18(Predicted)
color 
White to Orange to Green
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Safety

Hazard Codes 
Xi
Hazard Note 
Irritant
HS Code 
2908190090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C3172
Product name
4-Chloro-2-iodophenol
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$90
Updated
2025/07/31
TRC
Product number
C381755
Product name
4-Chloro-2-iodophenol
Packaging
10mg
Price
$45
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC11263
Product name
4-Chloro-2-iodo-phenol
Packaging
10g
Price
$260
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC11263
Product name
4-Chloro-2-iodo-phenol
Packaging
25g
Price
$450
Updated
2021/12/16
Matrix Scientific
Product number
083775
Product name
4-Chloro-2-iodophenol
Purity
97%
Packaging
10g
Price
$588
Updated
2021/12/16
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4-Chloro-2-iodophenol Chemical Properties,Usage,Production

Synthesis

95-85-2

71643-66-8

Synthesis Example 22 Synthesis of 3-cyano-5-chloro-2-hydroxyacetophenone: 2-amino-4-chlorophenol (50 g, 0.35 mol) was dissolved in 500 ml of 2.5N hydrochloric acid solution. The resulting solution was cooled to 0°C, at which temperature 25.25 g (0.37 mol) of sodium nitrite dissolved in 50 ml of water was added slowly and dropwise. The reaction mixture was stirred at 0°C for 30 min and then a pre-cooled solution of 70 g (0.42 mol) of potassium iodide dissolved in 100 ml of water was slowly added. Subsequently, the reaction mixture was gradually warmed to room temperature and stirred continuously at this temperature overnight. Upon completion of the reaction, the reaction mixture was extracted with ethyl acetate and the solvent was removed by reduced pressure distillation after combining the organic phases to give 89.7 g of 4-chloro-2-iodophenol in 99% yield.

References

[1] Patent: US6046212, 2000, A
[2] Patent: US6136848, 2000, A
[3] Patent: WO2003/84917, 2003, A1. Location in patent: Page/Page column 24-25
[4] Patent: WO2006/23852, 2006, A2. Location in patent: Page/Page column 88-90
[5] Journal of Medicinal Chemistry, 1997, vol. 40, # 7, p. 1075 - 1089

4-Chloro-2-iodophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-2-iodophenol Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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ShangHai DEMO Chemical Co.,Ltd
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400-021-7337 2355568890
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0086-21-50182339
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sales@demochem.com
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China
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Energy Chemical
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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China
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Shandong Xiya Chemical Co., Ltd
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0539-6365991
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3007715519@qq.com
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Shanghai Sunway Pharmaceutical Technology Co., Ltd
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021 51613951
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Hangzhou Yuhao Chemical Technology Co., Ltd
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+86-571-82880190
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Wuhan TCASChem Technology Co., Ltd.
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027-86697669 13986148687
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Nanjing Norris-Pharm Technology Co., Ltd
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+86-25-52131256
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China
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Shanghai potentpharm CO.,Ltd
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13524892556
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(86) 21 51969655, QQ: 263541193
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sales-cn@potentpharm.com
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China
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1011
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View Lastest Price from 4-Chloro-2-iodophenol manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
4-Chloro-2-iodophenol 71643-66-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2025-06-29
Career Henan Chemical Co
Product
4-Chloro-2-iodophenol 71643-66-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-09