ChemicalBook > CAS DataBase List > 4-Chloro-2-iodophenol

4-Chloro-2-iodophenol

Product Name: 4-Chloro-2-iodophenol
CAS No.: 71643-66-8
Chemical Name: 4-Chloro-2-iodophenol
Synonyms: 2-Iodo-4-chlorophenol;4-CHLORO-2-IODOPHENOL;Phenol, 4-chloro-2-iodo-
CBNumber: CB8293653
Molecular Formula: C6H4ClIO
Formula Weight: 254.45
MOL File: 71643-66-8.mol

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4-Chloro-2-iodophenol Property

Melting point:: 75.0 to 79.0 °C
Boiling point:: 225.1±20.0 °C(Predicted)
Density: 2.087±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: 8.07±0.18(Predicted)
color: White to Orange to Green

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Safety

Hazard Codes: Xi
Hazard Note: Irritant
HS Code: 2908190090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3172
Product name: 4-Chloro-2-iodophenol
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $90
Updated: 2025/07/31

TRC

Product number: C381755
Product name: 4-Chloro-2-iodophenol
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC11263
Product name: 4-Chloro-2-iodo-phenol
Packaging: 10g
Price: $260
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC11263
Product name: 4-Chloro-2-iodo-phenol
Packaging: 25g
Price: $450
Updated: 2021/12/16

Matrix Scientific

Product number: 083775
Product name: 4-Chloro-2-iodophenol
Purity: 97%
Packaging: 10g
Price: $588
Updated: 2021/12/16

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4-Chloro-2-iodophenol Chemical Properties,Usage,Production

Synthesis

95-85-2

71643-66-8

Synthesis Example 22 Synthesis of 3-cyano-5-chloro-2-hydroxyacetophenone: 2-amino-4-chlorophenol (50 g, 0.35 mol) was dissolved in 500 ml of 2.5N hydrochloric acid solution. The resulting solution was cooled to 0°C, at which temperature 25.25 g (0.37 mol) of sodium nitrite dissolved in 50 ml of water was added slowly and dropwise. The reaction mixture was stirred at 0°C for 30 min and then a pre-cooled solution of 70 g (0.42 mol) of potassium iodide dissolved in 100 ml of water was slowly added. Subsequently, the reaction mixture was gradually warmed to room temperature and stirred continuously at this temperature overnight. Upon completion of the reaction, the reaction mixture was extracted with ethyl acetate and the solvent was removed by reduced pressure distillation after combining the organic phases to give 89.7 g of 4-chloro-2-iodophenol in 99% yield.

References

[1] Patent: US6046212, 2000, A
[2] Patent: US6136848, 2000, A
[3] Patent: WO2003/84917, 2003, A1. Location in patent: Page/Page column 24-25
[4] Patent: WO2006/23852, 2006, A2. Location in patent: Page/Page column 88-90
[5] Journal of Medicinal Chemistry, 1997, vol. 40, # 7, p. 1075 - 1089

4-Chloro-2-iodophenol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Chloro-2-iodophenol manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: 4-Chloro-2-iodophenol 71643-66-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-06-29

Career Henan Chemical Co

Product: 4-Chloro-2-iodophenol 71643-66-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 150KG
Release date: 2019-07-09

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71643-66-8

Halides

Phenyls & Phenyl-Het