AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT)
- Product Name
- AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT)
- CAS No.
- 144409-98-3
- Chemical Name
- AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT)
- Synonyms
- -peptide (1-40) rat;β-Amyloid (1-40), rat;Rat amyloid β-protein 1-40;Rat aMyloid-β peptide 1-40;Rat aMyloid-beta peptide 1-40;Amyloid β-peptide (1-40) (rat);Beta-Amyloid (1-40), Mouse, Rat;Amyloid beta-peptide (1-40) (rat);Amyloid β-Protein (1-40) (mouse, rat);AMyloid b-Protein (1-40) (Mouse, rat)
- CBNumber
- CB8293800
- Molecular Formula
- C190H291N51O57S
- Formula Weight
- 0
- MOL File
- Mol file
AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT) Property
- storage temp.
- -15°C
- solubility
- Soluble to 1 mg/ml in 1% Ammonia
- form
- Solid
- color
- White to off-white
- Sequence
- H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
N-Bromosuccinimide Price
- Product number
- 2424
- Product name
- Amyloidbeta-peptide(1-40)(rat)
- Packaging
- 1
- Price
- $180
- Updated
- 2021/12/16
- Product number
- FA109563
- Product name
- Amyloid beta-Protein (1-40) (mouse, rat)
- Packaging
- 250ug
- Price
- $132.5
- Updated
- 2021/12/16
- Product number
- FA109563
- Product name
- Amyloid beta-Protein (1-40) (mouse, rat)
- Packaging
- 500ug
- Price
- $230
- Updated
- 2021/12/16
- Product number
- FA109563
- Product name
- Amyloid beta-Protein (1-40) (mouse, rat)
- Packaging
- 1mg
- Price
- $399
- Updated
- 2021/12/16
- Product number
- FA109563
- Product name
- Amyloid beta-Protein (1-40) (mouse, rat)
- Packaging
- 2mg
- Price
- $678
- Updated
- 2021/12/16
AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT) Chemical Properties,Usage,Production
Uses
β-Amyloid (1-40) (rat) is a rat form of the amyloid β-peptide, which accumulates as an insoluble extracellular deposit around neurons, giving rise to the senile plaques associated with Alzheimer's disease (AD). β-Amyloid (1-40) (rat) increases 45Ca2+ influx, induces neurodegeneration in the rat hippocampal neurons of the CA1 subfield. β-Amyloid (1-40) (rat) induces apoptosis. β-Amyloid (1-40) (rat) can be used for the research of Alzheimer's disease[1][2].
in vivo
β-Amyloid (1-40) (rat) (1.7 mg; ICV, for 7 d; swiss and C57BL/6 mice) induces the learning and memory deficits in mice[3].
| Animal Model: | Swiss and C57BL/6 mice[3] |
| Dosage: | 1.7 mg |
| Administration: | Intracerebroventrical injection; for 7 days |
| Result: | Presented spatial learning and memory impairments. |
storage
Desiccate at -20°C
References
[1] MacManus A, et, al. Enhancement of (45)Ca(2+) influx and voltage-dependent Ca(2+) channel activity by beta-amyloid-(1-40) in rat cortical synaptosomes and cultured cortical neurons. Modulation by the proinflammatory cytokine interleukin-1beta. J Biol Chem. 2000 Feb 18;275(7):4713-8. DOI:10.1074/jbc.275.7.4713
[2] Miguel-Hidalgo JJ, et, al. Beta-amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. Acta Neuropathol. 1998 May;95(5):455-65. DOI:10.1007/s004010050825
[3] Prediger RD, et, al. Differential susceptibility following beta-amyloid peptide-(1-40) administration in C57BL/6 and Swiss albino mice: Evidence for a dissociation between cognitive deficits and the glutathione system response. Behav Brain Res. 2007 Feb 27;177(2):205-13. DOI:10.1016/j.bbr.2006.11.032
AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT) Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT) manufacturers
- Product
- AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT) 144409-98-3
- Price
- US $0.10-0.30/kg
- Min. Order
- 1kg
- Purity
- ≥98.0%
- Supply Ability
- 20 tons
- Release date
- 2024-01-06
- Product
- AMYLOID BETA-PROTEIN (1-40) (MOUSE, RAT) 144409-98-3
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2020-03-05