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Mirin

Product Name
Mirin
CAS No.
1198097-97-0
Chemical Name
Mirin
Synonyms
CS-2593;(Z)-Mirin;(Z)-Mirin,Inhibitor,(Z)Mirin,(Z) Mirin,inhibit;(Z)-2-Amino-5-(4-hydroxybenzylidene)thiazol-4(5H)-one;(5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone;4(5H)-Thiazolone, 2-amino-5-[(4-hydroxyphenyl)methylene]-, (5Z)-;(5Z) -2-amino-5- [(4-hydroxyphenyl) methylene] -4 (5H) - thiazolidone
CBNumber
CB83037397
Molecular Formula
C10H8N2O2S
Formula Weight
220.25
MOL File
1198097-97-0.mol
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Mirin Property

Boiling point:
441.6±55.0 °C(Predicted)
Density 
1.49±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
insoluble in EtOH; insoluble in H2O; ≥9.3 mg/mL in DMSO
form 
solid
pka
8.70±0.30(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
M364938
Product name
Mirin
Packaging
50mg
Price
$225
Updated
2021/12/16
ApexBio Technology
Product number
B5389
Product name
Mirin
Packaging
50mg
Price
$228
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
INB0004757
Product name
2-AMINO-5-[(4-HYDROXYPHENYL)METHYLENE]-, (5Z)-4(5H)-THIAZOLONE
Purity
95.00%
Packaging
5MG
Price
$502.78
Updated
2021/12/16
ApexBio Technology
Product number
B5389
Product name
Mirin
Packaging
10mM(in 1mL DMSO)
Price
$50
Updated
2021/12/16
ApexBio Technology
Product number
B5389
Product name
Mirin
Packaging
10mg
Price
$83
Updated
2021/12/16
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Mirin Chemical Properties,Usage,Production

Uses

Mirin is an MRN-ATM pathway inhibitor blocking 3’ and 5’ exonuclease activity associated with Mre11, inducing G2 cell cycle arrest.

Biological Activity

mirin is a potent mrn complex inhibitor. mirin inhibits mre11-associated exonuclease activity, rather than alters dna-binding or mrn complex formation. moreover, mirin prevents mrn-dependent activation of atm in response to dna double-strand breaks, with an ic50 value of 12 μm. the mrn complex acts as a dna damage sensor, responsible for maintaining genome stability during dna replication, promoting homology-dependent dna repair and activating atm. the mrn-atm pathway plays an essential role in sensing and signaling from dna double-strand breaks.1. dupré a, boyer-chatenet l, sattler rm, et al. a forward chemical genetic screen reveals an inhibitor of the mre11-rad50-nbs1 complex. nature chemical biology, 2008, 4(2): 119-125.

storage

Store at +4°C

Mirin Preparation Products And Raw materials

Raw materials

Preparation Products

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Mirin Suppliers

Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77
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View Lastest Price from Mirin manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Mirin 1198097-97-0
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000ton
Release date
2023-08-29
Career Henan Chemical Co
Product
(5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone 1198097-97-0
Price
US $1.00/ASSAYS
Min. Order
1ASSAYS
Purity
95%~99%
Supply Ability
per week:100kg
Release date
2019-09-05

1198097-97-0, MirinRelated Search:


  • (5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone
  • CS-2593
  • 4(5H)-Thiazolone, 2-amino-5-[(4-hydroxyphenyl)methylene]-, (5Z)-
  • (Z)-2-Amino-5-(4-hydroxybenzylidene)thiazol-4(5H)-one
  • (Z)-Mirin
  • (Z)-Mirin,Inhibitor,(Z)Mirin,(Z) Mirin,inhibit
  • (5Z) -2-amino-5- [(4-hydroxyphenyl) methylene] -4 (5H) - thiazolidone
  • 1198097-97-0