ChemicalBook > CAS DataBase List > N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose

N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose

Product Name
N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose
CAS No.
38854-46-5
Chemical Name
N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose
Synonyms
nacos-6;Brn 0001006;n-acetylchitohexaose;N-acetylated chitohexaose;chitohexaose,hexa-n-acetyl;n-acetylglucosaminehexamer;HEXA-(N-ACETYL) CHITOHEXAOSE;Hexaacetyl-Chitohexaose- 10mg;N,N,N,N,N-Hexaacetylchitohexaose;Chitohexaose, hexa-N-acetyl (6ci)
CBNumber
CB8304793
Molecular Formula
C48H80N6O31
Formula Weight
1237.17
MOL File
38854-46-5.mol
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N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose Property

Melting point:
>250°C (dec.)
alpha 
-11.4 º (in H2O)
Boiling point:
1652.6±65.0 °C(Predicted)
Density 
1.60±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Water (Slightly), Methanol (Slightly)
form 
Solid
pka
12.72±0.70(Predicted)
color 
White to Off-White
Stability:
Hygroscopic
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Safety

Safety Statements 
24/25
WGK Germany 
3
RTECS 
LZ6653000
HS Code 
29400090
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
17864
Product name
Hexa-N-acetylchitohexaose
Purity
≥95%
Packaging
500μg
Price
$121
Updated
2024/03/01
Cayman Chemical
Product number
17864
Product name
Hexa-N-acetylchitohexaose
Purity
≥95%
Packaging
1mg
Price
$218
Updated
2024/03/01
Cayman Chemical
Product number
17864
Product name
Hexa-N-acetylchitohexaose
Purity
≥95%
Packaging
5mg
Price
$601
Updated
2024/03/01
TRC
Product number
H290750
Product name
N,N’,N’’,N’’’,N’’’’,N’’’’’-Hexaacetylchitohexaose
Packaging
10mg
Price
$1015
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CRB0000532
Product name
N,N',N'',N''',N'''',N'''''-HEXAACETYLCHITOHEXAOSE
Purity
95.00%
Packaging
10MG
Price
$1871.1
Updated
2021/12/16
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N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

cation exchanger ~1.4 meq/g

Uses

Various publications have cited the use of N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose in mutagenesis studies due to its antitumor effects.
Hexa-N-acetylchitohexaose is a hexamer of N-acetylglucosamine, a subunit of the natural polymer chitin. It functions as an elicitor in plants, inducing the expression of chitinases.Like chitin and some of its derivatives, hexa-N-acetylchitohexaose is a substrate of lysozyme.It also binds LysM domains on certain proteins, including an endopeptidase of T. thermophilus.Hexa-N-acetylchitohexaose heightens the immune response against Pseudomonas and Listeria in mice, stimulates cytokine secretion in mesenchymal stem cells, and inhibits nitric oxide production by activated macrophages.

Uses

Studied for anti-tumor effects

Reactions

Chitohexaose has attracted wide interest due to its special bioactivities and these potential activities are significantly related to N-acetylation.
Herein, six chitohexaose fractions with different degrees of acetylation were prepared by selective N-acetylation and ion-exchange chromatography and further analyzed by ESI/MS.
It is revealed that all the six N-acetylated chitohexaoses were of single molecular weight, the molecular weights of which were exactly assigned to 1026.44 Da, 1068.44 Da, 1110.48 Da, 1152.48 Da, 1194.49 Da, and 1236.48 Da, respectively. These results suggested that the six prepared N-acetylated chitohexaoses were N-acetylchitohexaose (D5A1), di-N-acetylchitohexaose (D4A2), tri-N-acetylchitohexaose (D3A3), tetra-N-acetylchitohexaose (D2A4), penta-N-acetylchitohexaose (D1A5), and hexa-N-acetylchitohexaose (A6), respectively, which are of great significance to screen their bioactivities and discover well-defined chitooligosaccharide molecules as potential drugs.

  1. Access to N-acetylated chitohexaose with well-defined degrees of acetylation
  2. Li, Kecheng; Xing, Ronge; Liu, Song; Qin, Yukun; Li, Pengcheng - BioMed Research International, 2017, vol. 2017

N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose Preparation Products And Raw materials

Raw materials

Preparation Products

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N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose Suppliers

Canada 1 China 51 France 1 Germany 1 India 1 Switzerland 1 United Kingdom 4 United States 7 Global 67
Carbosynth
Tel
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Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6005
Advantage
58
Carbosynth Limited
Tel
--
Fax
--
Email
sales@carbosynth.com
Country
United Kingdom
ProdList
6581
Advantage
61
MOLEKULA Ltd.
Tel
--
Fax
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Email
kevinbanks@molekula.com
Country
United Kingdom
ProdList
6140
Advantage
66
Dextra Laboratories Ltd.
Tel
--
Fax
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Email
dextra@dextra-labs.co.uk
Country
United Kingdom
ProdList
378
Advantage
60
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View Lastest Price from N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
N,N,N,N,N,N-Hexaacetylchitohexaose 38854-46-5
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-19

38854-46-5, N,N',N'',N''',N'''',N'''''-HexaacetylchitohexaoseRelated Search:

N,N'-Diacetylchitobiose N-Acetyl-L-glutamic acid N-Acetyl-L-cysteine D-hexamannuronic acid hexasodium salt D-mannuronic acid sodium salt D-dimannuronic acid disodium salt D-heptamannuronic acid heptasodium salt D-tetramannuronic acid tetrasodium salt D-octamannuronic acid octasodium salt D-pentamannuronic acid pentasodium salt manninotriose Perisesaccharide B D-trimannuronic acid trisodium salt N',N'',N'''-Tetraacetylchitotetraose N,N',N''-TRIACETYLCHITOTRIOSE N-ACETYLCHITOOCTAOSE N',N'',N''',N''''-Pentaacetylchitopentaose N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose

  • HEXA-(N-ACETYL) CHITOHEXAOSE
  • GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC-BETA1-4GLCNAC
  • GLCNAC1-B-4-GLCNAC1-B-4-GLCNAC1-B-4GLCNAC1-B-4GLCNAC1-B-4GLCNAC
  • N,N',N'',N''',N'''',N'''''-Hexa-O-acetylchitohexaose
  • Brn 0001006
  • Chitohexaose, hexa-N-acetyl (6ci)
  • D-Glucose, o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-
  • N-acetylated chitohexaose
  • O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-D-glucose
  • cetylamino)-2-deoxy-beta-d-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-
  • chitohexaose,hexa-n-acetyl
  • d-glucose,o-2-(acetylamino)-2-deoxy-beta-d-glucopyranosyl-(1-4)-o-2-(acetylami
  • n-acetylchitohexaose
  • n-acetylglucosaminehexamer
  • n-acetylglucosaminehexasaccharide
  • nacos-6
  • no)-2-deoxy-beta-d-glucopyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-d-gluc
  • opyranosyl-(1-4)-o-2-(acetylamino)-2-deoxy-beta-d-glucopyranosyl-(1-4)-o-2-(a
  • N(I),N(II),N(III),N(IV),N(V),N(VI)-HEXAACETYLCHITOHEXAOSE
  • N,N',N'',N''',N'''',N'''''-HEXAACETYL CHITOHEXAOSE
  • N,N',N,N''',N'''',N'''''-HEXAACETYLCHITOHEXAOSE
  • N,N,N,N,N-Hexaacetylchitohexaose
  • Hexaacetyl-Chitohexaose- 10mg
  • D-Glucose, O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-O-2-(acetylamino)-2-deoxy-β-D-glucopyranosyl-(1→4)-2-(acetylamino)-2-deoxy-
  • N,N',N'',N''',N'''',N'''''-Hexaacetylchitohexaose USP/EP/BP
  • N,N',N'',N''',N'''',N'''''-Hexa-O-acetylchitohexaose
  • 38854-46-5
  • C48H80N6O31
  • BioChemical
  • Cell Signaling and Neuroscience
  • Cell Biology
  • Immune Cell Signaling and Blood
  • Immune System Regulation
  • Immunomodulators and Antibiotics
  • Oligosaccharides