ChemicalBook > CAS DataBase List > Mal-PEG1-t-butyl ester
Mal-PEG1-t-butyl ester
- Product Name
- Mal-PEG1-t-butyl ester
- CAS No.
- 810677-16-8
- Chemical Name
- Mal-PEG1-t-butyl ester
- Synonyms
- Mal-PEG1-Boc;Mal-PEG1-t-butyl ester;tert-butyl 3-[2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy]propanoate;Propanoic acid, 3-[2-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB83062528
- Molecular Formula
- C13H19NO5
- Formula Weight
- 269.29
- MOL File
- 810677-16-8.mol
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Mal-PEG1-t-butyl ester Property
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-22322
- Product name
- Mal-PEG1-t-butylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
Apolloscientific
- Product number
- BIPG1514
- Product name
- Mal-PEG1-t-butyl ester
- Packaging
- 100mg
- Price
- $623
- Updated
- 2021/12/16
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Mal-PEG1-t-butyl ester Chemical Properties,Usage,Production
Description
Mal-PEG1-t-butyl ester is a PEG linker containing a maleimide group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
Uses
Mal-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Mal-PEG1-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Mal-PEG1-t-butyl ester Suppliers
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View Lastest Price from Mal-PEG1-t-butyl ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- Mal-PEG1-COOtBu 810677-16-8
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-27
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