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Sacubitril Impurity 7

Product Name
Sacubitril Impurity 7
CAS No.
149709-44-4
Chemical Name
Sacubitril Impurity 7
Synonyms
LBQ657;LCZ696-4;Sacubitrilat;Deethyl Sakuba;LCZ-696 Impurity 1;SACUBITRIL DI ACID;Diacid of Sacubitril;LCZ696 impurities124;LBQ-657(Sacubitrilat);Sacubitrilat (LBQ-657)
CBNumber
CB83133439
Molecular Formula
C22H25NO5
Formula Weight
383.44
MOL File
149709-44-4.mol
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Sacubitril Impurity 7 Property

Boiling point:
705.4±60.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMF:30.0(Max Conc. mg/mL);78.24(Max Conc. mM)
DMSO:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:77.0(Max Conc. mg/mL);200.81(Max Conc. mM)
Ethanol:PBS (pH 7.2) (1:1):0.5(Max Conc. mg/mL);1.3(Max Conc. mM)
form 
A crystalline solid
pka
4.59±0.23(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
19829
Product name
LBQ657
Purity
≥98%
Packaging
1mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
19829
Product name
LBQ657
Purity
≥98%
Packaging
5mg
Price
$131
Updated
2024/03/01
Cayman Chemical
Product number
19829
Product name
LBQ657
Purity
≥98%
Packaging
10mg
Price
$245
Updated
2024/03/01
Cayman Chemical
Product number
19829
Product name
LBQ657
Purity
≥98%
Packaging
25mg
Price
$894
Updated
2021/12/16
TRC
Product number
D288245
Product name
DesethylSacubitril
Packaging
10mg
Price
$580
Updated
2021/12/16
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Sacubitril Impurity 7 Chemical Properties,Usage,Production

Uses

Desethyl Sacubitril is an impurity in the synthesis of Sacubitril (S080895), an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.

Sacubitril Impurity 7 Preparation Products And Raw materials

Raw materials

Preparation Products

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149709-44-4, Sacubitril Impurity 7Related Search:

Sacubitril Impurity 72 Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Sacubitril Impurity 3 Sacubitril Impurity 19 Sacubitril Impurity 23 ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Sacubitril Impurity 21 Sacubitril Impurity 6 Sacubitril Impurity 7 Sacubitril Impurity 5 Sacubitril Impurity 20 Sacubitril Impurity 24 HCl Sildenafil EP Impurity G Sacubitril Impurity 8

  • (2R,4S)-4-(3-carboxypropanoylamino)-2-methyl-5-(4-phenylphenyl)pentanoic acid
  • LCZ696-4
  • Diacid of Sacubitril
  • LBQ657
  • Sacubitrilat
  • LCZ-696 Impurity 1
  • Sacubitrilat (LBQ-657)
  • Sacubitril Desethyl Impurity
  • LCZ696 Impurity 900-04
  • Deethyl Sakuba
  • Sacubitril metabolite LBQ 657
  • [1,1'-Biphenyl]-4-pentanoic acid, γ-[(3-carboxy-1-oxopropyl)amino]-α-methyl-, (αR,γS)-
  • 4-[[(1S,3R)-1-[([1,1'-Biphenyl]-4-yl)methyl]-3-methyl-4-hydroxy-4-oxobutyl]amino]-4-oxobutanoic acid
  • (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(3-carboxypropanamido)- 2-methylpentanoic aci
  • Diacid of Sacubitril/ Sacubitril Desethyl Impurity/ Sacubitrilat
  • LCZ696 impurities124
  • Sacubitril metabolite LBQ 657Q: What is Sacubitril metabolite LBQ 657 Q: What is the CAS Number of Sacubitril metabolite LBQ 657 Q: What is the storage condition of Sacubitril metabolite LBQ 657 Q: What are the applications of Sacubitril metabolite LBQ 657
  • quinoline,6-bromo-7-chloro-
  • SACUBITRIL DI ACID
  • Salcubatra calcium impurity J
  • LBQ-657(Sacubitrilat)
  • LCZ696 impurity 900-04（LBQ657）
  • Sacubitril Diacid Impurity
  • (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-(3-carboxypropanamido)-2-methylpentanoic acid
  • Valsartan Impurity D-1
  • Sacubitril Impurity 4 (LBQ-657) (desethyl) (Sacubitrilat)
  • Sacubitril Impurity 4 (LBQ-657) (desethyl) (Sacubitrilat)
  • Sacubitril metabolite LBQ 657-[d4]
  • 149709-44-4
  • 14709-44-4