ChemicalBook > CAS DataBase List > Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate

Product Name
Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate
CAS No.
1038924-97-8
Chemical Name
Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate
Synonyms
LCZ700;LCZ696-9;LCZ-696-006-RS;LCZ-696-006-2R4S;LCZ-696 Impurity 4;Sakubiter Impurity 2;Valsartan Impurity 77;SACUBITRIL SUCCINIMIDE;LCZ-696 Impurity 550-06;Salcubatra calcium impurity P
CBNumber
CB62995782
Molecular Formula
C24H27NO4
Formula Weight
393.48
MOL File
1038924-97-8.mol
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Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Property

Boiling point:
581.3±50.0 °C(Predicted)
Density 
1.166±0.06 g/cm3(Predicted)
solubility 
Chloroform (Sparingly), Ethyl Acetate (Slightly)
form 
Solid
pka
-1.52±0.20(Predicted)
color 
White to Off-White Waxy
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D486550
Product name
2,5-DioxopyrrolidineSacubitril
Packaging
5mg
Price
$290
Updated
2021/12/16
TRC
Product number
D486550
Product name
2,5-DioxopyrrolidineSacubitril
Packaging
25mg
Price
$1210
Updated
2021/12/16
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Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Chemical Properties,Usage,Production

Uses

Sacubitril Impurity 2 is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Suppliers

China 61 India 2 United States 4 Global 67
Adamas Reagent, Ltd.
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400-6009262 16621234537
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
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Beijing Comparison Pharmaceutical Technology Co., Ltd
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010-010-52878169 15801002657
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sales@bjcomparison.com
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China
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Changzhou Renaissance Chem Co. Ltd
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86-519-86202821
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ChemStrong Scientific Co.,Ltd
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Wuxi Zhongkun Biochemical Technology Co., Ltd.
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Nanjing XiZe Biotechnology CO., Ltd.
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PharmaSea Pharmaceutical Tech.
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BOC Sciences
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Roark Standards
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1038924-97-8, Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoateRelated Search:

Sacubitril Impurity 21 Valsartan ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester LCZ696 interMediate AHU-377 (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate LCZ696 InteMediate Sacubitril Impurity 72 LCZ696 LCZ Impurity (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate AHU-377 (heMicalciuM salt) 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- sacubitril

  • LCZ696-9
  • LCZ696(valsartan + sacubitril) impurity 9
  • ethyl(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate
  • Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate
  • LCZ700
  • (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate
  • LCZ-696 Impurity 4
  • LCZ-696-006-RS
  • LCZ-696-006-2R4S
  • Sacubitril 2,5-Dioxopyrrolidine
  • Valsartan Impurity 77
  • Sakubiter Impurity 2
  • 1-Pyrrolidinebutanoic acid, γ-([1,1'-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-, ethyl ester, (αR,γS)-
  • (2R,4S)-5-(Biphenyl-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester
  • SACUBITRIL SUCCINIMIDE
  • Salcubatra calcium impurity P
  • Valsartan Impurity 40（Sacubitril impurity 40）
  • Shakubatura calcium impurity M
  • Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate
  • LCZ-696 Impurity 550-06
  • 1038924-97-8
  • LCZ696