ChemicalBook > CAS DataBase List > Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate

Product Name: Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate
CAS No.: 1038924-97-8
Chemical Name: Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate
Synonyms: LCZ700;LCZ696-9;LCZ-696-006-RS;LCZ-696-006-2R4S;LCZ-696 Impurity 4;Sekbi Qu Impurity 7;Sakubiter Impurity 2;Valsartan Impurity 77;SACUBITRIL SUCCINIMIDE;LCZ-696 Impurity 550-06
CBNumber: CB62995782
Molecular Formula: C24H27NO4
Formula Weight: 393.48
MOL File: 1038924-97-8.mol

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Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Property

Boiling point:: 581.3±50.0 °C(Predicted)
Density: 1.166±0.06 g/cm3(Predicted)
solubility: Chloroform (Sparingly), Ethyl Acetate (Slightly)
form: Solid
pka: -1.52±0.20(Predicted)
color: White to Off-White Waxy

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D486550
Product name: 2,5-DioxopyrrolidineSacubitril
Packaging: 5mg
Price: $290
Updated: 2021/12/16

TRC

Product number: D486550
Product name: 2,5-DioxopyrrolidineSacubitril
Packaging: 25mg
Price: $1210
Updated: 2021/12/16

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Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Chemical Properties,Usage,Production

Uses

Sacubitril Impurity 2 is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Preparation Products And Raw materials

Raw materials

Preparation Products

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1038924-97-8, Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoateRelated Search:

Sacubitril Impurity 21 Valsartan ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester LCZ696 interMediate AHU-377 (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate LCZ696 InteMediate Sacubitril Impurity 72 LCZ696 LCZ Impurity (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate AHU-377 (heMicalciuM salt) 2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- sacubitril

LCZ696-9

LCZ696(valsartan + sacubitril) impurity 9

ethyl(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate

Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate

LCZ700

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoate

LCZ-696 Impurity 4

LCZ-696-006-RS

LCZ-696-006-2R4S

Sacubitril 2,5-Dioxopyrrolidine

Valsartan Impurity 77

Sakubiter Impurity 2

1-Pyrrolidinebutanoic acid, γ-([1,1'-biphenyl]-4-ylmethyl)-α-methyl-2,5-dioxo-, ethyl ester, (αR,γS)-

(2R,4S)-5-(Biphenyl-4-yl)-4-(2,5-dioxopyrrolidin-1-yl)-2-methylpentanoic acid ethyl ester

SACUBITRIL SUCCINIMIDE

Salcubatra calcium impurity P

Valsartan Impurity 40（Sacubitril impurity 40）

Shakubatura calcium impurity M

LCZ-696 Impurity 550-06

Sekbi Qu Impurity 7

1038924-97-8

LCZ696