BOC-PHE-N(OCH3)CH3

Product Name: BOC-PHE-N(OCH3)CH3
CAS No.: 87694-53-9
Chemical Name: BOC-PHE-N(OCH3)CH3
Synonyms: BOC-PHE-N(OCH3)CH3;Boc-L-Phe-N(OCH3)CH3;BOC-PHE-N(OCH3)CH3 USP/EP/BP;BOC-L-PHENYLALANINE N-METHOXY-N-METHYL AMIDE;N-Boc-N-methoxy-N-methyl-L-phenylalaninamide;N-Boc-L-phenylalanine N'-Methoxy-N'-MethylaMide;N-ALPHA-T-BOC-L-PHENYLALANINE N-METHOXY-N-METHYL AMIDE;Boc-L-phenylalanineN-methoxy-N-methyl amide≥ 98% (HPLC);(S)-2-(Boc-amino)-N-methoxy-N-methyl-3-phenylpropanamide;tert-butyl N-[(1S)-1-[methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate
CBNumber: CB8320872
Molecular Formula: C16H24N2O4
Formula Weight: 308.37
MOL File: 87694-53-9.mol

More

Less

BOC-PHE-N(OCH3)CH3 Property

storage temp.: Sealed in dry,2-8°C
solubility: Chloroform, Dichloromethane
form: Oil
color: Light Yellow

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

TRC

Product number: B657200
Product name: N-Boc-N-methoxy-N-methyl-L-phenylalaninamide
Packaging: 100mg
Price: $85
Updated: 2021/12/16

Usbiological

Product number: 004475
Product name: N-Boc-N-methoxy-N-methyl-L-phenylalaninamide
Packaging: 100mg
Price: $425
Updated: 2021/12/16

Usbiological

Product number: 262956
Product name: N-Boc-N-methoxy-N-methyl-L-phenylalaninamide
Packaging: 50mg
Price: $425
Updated: 2021/12/16

Chem-Impex

Product number: 03806
Product name: Boc-L-phenylalanine -methoxy--methyl amide
Purity: ≥ 98% (HPLC, Chiral purity)
Packaging: 1G
Price: $35
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB18972
Product name: N-Boc-N-methoxy-N-methyl-L-phenylalaninamide
Packaging: 1g
Price: $100
Updated: 2021/12/16

More

Less

BOC-PHE-N(OCH3)CH3 Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Oil

Uses

Reduced by LiAlH4 to give the corresponding Boc amino acid aldehyde.

Uses

An intermediate for the synthesis of some HIV protease inhibitors.

Synthesis

13734-34-4

1117-97-1

87694-53-9

GENERAL PROCEDURE: Methoxymethylamine (0.360 g, 6.0 mmol) and BOC-L-phenylalanine (0.244 g, 2.0 mmol) were dissolved in anhydrous toluene (10 mL) and stirred for 10 min at 0 °C. Subsequently, a solution of phosphorus trichloride (0.137 g, 1.0 mmol) in anhydrous toluene (2 mL) was slowly added dropwise to the reaction mixture. The reaction system was gradually warmed up to room temperature and then stirred for 0.5 h at 60 °C. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was cooled to room temperature, quenched with saturated sodium bicarbonate solution (20 mL) and extracted with ethyl acetate (3 x 10 mL). The organic phases were combined and dried with anhydrous magnesium sulfate. The solvent was removed by concentration under reduced pressure and the resulting crude product was purified by column chromatography (silica gel, petroleum ether-ethyl acetate, 3:2) to afford the target compound (S)-(tert-butyl (S)-(1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate as a colorless oil in 320 mg (97%) yield.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 12, p. 3229 - 3232
[2] Journal of Medicinal Chemistry, 1992, vol. 35, # 4, p. 641 - 662
[3] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 20, p. 2855 - 2858
[4] Heteroatom Chemistry, 2003, vol. 14, # 7, p. 603 - 606
[5] Journal of Medicinal Chemistry, 2013, vol. 56, # 23, p. 9556 - 9568

BOC-PHE-N(OCH3)CH3 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BOC-PHE-N(OCH3)CH3 Suppliers

Canada 1 China 32 India 2 United Kingdom 5 United States 9 Global 49

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Chengdu Forest Science and Technology Development Co., Ltd.

Tel: 18030648795
Fax: 028-61777050
Email: sales@cdforestchem.com
Country: China
ProdList: 1999
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828 4008675858
Fax: +86-512-56316826
Email: sales@amateksci.com
Country: China
ProdList: 9874
Advantage: 55

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Henan Weituxi Chemical Technology Co., Ltd.

Tel: 0371-63284658 18135795563
Fax: QQ:2885349392
Email: 2885349392@qq.com
Country: China
ProdList: 9992
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

Hubei xin bonus chemical co. LTD

Tel: 86-13657291602
Fax: 027-59338440
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 22963
Advantage: 58

Jiangsu Hongmin Pharmaceutical Co., Ltd.

Tel: 18221292452
Email: fannieliu@glschina.com
Country: China
ProdList: 6798
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49975
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

Tel: 021-51816796-820 13611835272
Fax: 021-5161 3951
Email: sales2@sunwaypharm.com
Country: China
ProdList: 44119
Advantage: 58

Shijizhuang Zhoukun Pharmaceutical Technology Co., LTD

Tel: 0311-83784138 18633934202
Email: zhoukunpharma@163.com
Country: China
ProdList: 2125
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-6005915
Email: sales@picasso-e.com
Country: China
ProdList: 39653
Advantage: 58

Shanghai Lingfu Pharmaceutical Research Co. LTD

Tel: +86(21)5895 0110 19945755304
Email: sales@chemany.com
Country: China
ProdList: 9984
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 17801761073
Email: Gsiyu@solarbio.com
Country: China
ProdList: 50751
Advantage: 58

Shanghai Jieshikai Biotechnology Co. , Ltd.

Tel: 021-57520305 13795461237
Email: zhuruyan@jskchem.com
Country: China
ProdList: 49234
Advantage: 58

Shaanxi Xihua Chemical Industry Co., Ltd

Tel: 029-81136151 17392212881
Email: 1095@dideu.com
Country: China
ProdList: 10001
Advantage: 58

Hubei Danding Pharmaceutical Technology Co., Ltd

Tel: 17701422019
Email: 1559451077@qq.com
Country: China
ProdList: 8167
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Shanghai meikai technology co., ltd

Tel: 021-68689288 15300790979
Fax: wechat 18721550091
Email: info@mkbio.com.cn
Country: China
ProdList: 5000
Advantage: 58

DAYANG CHEM (HANGZHOU) CO.,LTD

Tel: +86-88938639 +86-17705817739
Email: info@dycnchem.com
Country: China
ProdList: 53899
Advantage: 58

Sichuan Biosynce Pharmatech Co., Ltd.

Tel: +8619950309693
Email: diane@biosynce.com
Country: China
ProdList: 4871
Advantage: 58

HANGZHOU LEAP CHEM CO., LTD.

Tel: +86-571-87711850
Email: market18@leapchem.com
Country: China
ProdList: 43339
Advantage: 58

Aromsyn Co., Ltd.

Tel: +86-0571-85585865 +8613336024896
Email: CB@aromsyn.com
Country: China
ProdList: 19183
Advantage: 58

Absin Bioscience Inc.

Tel: --
Fax: --
Email: chenjw@absin.cn
Country: CHINA
ProdList: 6208
Advantage: 58

Shanghai PI Chemicals Ltd.

Tel: --
Fax: --
Email: sales@pipharm.com
Country: China
ProdList: 6344
Advantage: 56

87694-53-9, BOC-PHE-N(OCH3)CH3Related Search:

N-HYDROXY-3-PHENYL-PROPIONAMIDE BOC-ALA-N(OCH3)CH3 BOC-CCK 33 BOC-GLYCINE N,O-DIMETHYLHYDROXAMIDE OTAVA-BB 1037847 CIVENTICHEM CV-4039 N-METHOXY-N-METHYL-3-PHENYL-PROPIONAMIDE BOC-PHE-N(OCH3)CH3

BOC-PHE-N(OCH3)CH3

BOC-L-PHENYLALANINE N-METHOXY-N-METHYL AMIDE

N-[(1S)-2-(Methoxymethylamino)-2-oxo-1-(phenylmethyl)ethyl]carbamic Acid 1,1-Dimethylethyl Ester

N-Boc-N-methoxy-N-methyl-L-phenylalaninamide

tert-Butyl [(1S)-1-benzyl-2-[methoxy(methyl)amino]-2-oxoethyl]carbamate

N-Boc-L-phenylalanine N'-Methoxy-N'-MethylaMide

Boc-L-Phe-N(OCH3)CH3

Boc-L-phenylalanineN-methoxy-N-methyl amide≥ 98% (HPLC)

tert-butyl N-[(1S)-1-[methoxy(methyl)carbamoyl]-2-phenylethyl]carbamate

N-ALPHA-T-BOC-L-PHENYLALANINE N-METHOXY-N-METHYL AMIDE

(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate

Carbamic acid, N-[(1S)-2-(methoxymethylamino)-2-oxo-1-(phenylmethyl)ethyl]-, 1,1-dimethylethyl ester

BOC-PHE-N(OCH3)CH3 USP/EP/BP

(S)-2-(Boc-amino)-N-methoxy-N-methyl-3-phenylpropanamide

87694-53-9

Amino Acids 13C, 2H, 15N

Amino Acids & Derivatives

Chiral Reagents