NARINGENIN

Product Name: NARINGENIN
CAS No.: 67604-48-2
Chemical Name: NARINGENIN
Synonyms: 5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)CHROMAN-4-ONE;rac Naringenin;BE-14348A;()-Naringenin;Naringenin-RM;D4-Naringenin;(±)-Naringenin;(R,S)-Naringenin;TIMTEC-BB SBB006461;Naringenin Standard
CBNumber: CB8325312
Molecular Formula: C15H12O5
Formula Weight: 272.25
MOL File: 67604-48-2.mol

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NARINGENIN Property

Melting point:: 247-250 °C (lit.)
Boiling point:: 577.5±50.0 °C(Predicted)
Density: 1.485
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
pka: 7.52±0.40(Predicted)
form: Solid
color: Pale Yellow to Pale Brown
biological source: Citrus paradisi Macf.
Water Solubility: Soluble in ethanol (50 mg/ml), DMSO, methanol, and ammonium hydroxide (50 mg/ml). Insoluble in water (almost)
Merck: 14,6424
InChI: InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2
InChIKey: FTVWIRXFELQLPI-UHFFFAOYSA-N
SMILES: C1(C2=CC=C(O)C=C2)OC2=CC(O)=CC(O)=C2C(=O)C1
CAS DataBase Reference: 67604-48-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
RIDADR: 3077
WGK Germany: 3
RTECS: DJ2981530
HS Code: 29329990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W530098
Product name: Naringenin
Purity: natural (US), 98%
Packaging: 1 unit
Price: $49.38
Updated: 2025/07/31

Sigma-Aldrich

Product number: W530098
Product name: Naringenin
Purity: natural (US), 98%
Packaging: 1 unit
Price: $49.38
Updated: 2025/07/31

Sigma-Aldrich

Product number: N5893
Product name: (±)-Naringenin
Purity: ≥95%
Packaging: 1g
Price: $58.2
Updated: 2025/07/31

Sigma-Aldrich

Product number: 52186
Product name: (±)-Naringenin
Purity: analytical standard
Packaging: 50mg
Price: $155
Updated: 2025/07/31

TCI Chemical

Product number: N0072
Product name: Naringenin
Purity: >93.0%(HPLC)(T)
Packaging: 5g
Price: $66
Updated: 2025/07/31

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NARINGENIN Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow to Pale Brown Solid

Uses

A PI 3-kinase inhibitor.

Uses

The aglucon of Naringin. Inhibitory mechanism of Naringenin against carcinogenic acrylamide formation and nonenzymic browning in Maillard model reactions.

Definition

ChEBI: Naringenin is a trihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5, 6 and 4'. It is a trihydroxyflavanone and a member of 4'-hydroxyflavanones.

General Description

Naringenin is a bioactive flavonoid found in citrus and grapefruit.

in vivo

(±)-Naringenin (50 mg/kg, orally, once a day for ten days) significantly reduces the severity of DSS-induced colitis in mice and downregulats pro-inflammatory mediators (iNOS, ICAM-1, MCP-1, Cox2, TNF-α, and IL-6 mRNA) in the colonic mucosa^[2].

Animal Model:	C57BL/6^[2]
Dosage:	50 mg/kg
Administration:	Oral; daily; 10 days
Result:	Reduced the severity of DSS-induced colitis in mice, downregulated pro-inflammatory mediators (iNOS, ICAM-1, MCP-1, Cox2, TNF-α, and IL-6 mRNA) in the colonic mucosa, inhibited the increase in TLR4 mRNA and protein levels, and reduced the phosphorylated NF-κB p65 protein level.

IC 50

NF-κB; Caspase 9

NARINGENIN Preparation Products And Raw materials

Raw materials

Preparation Products

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NARINGENIN Suppliers

Americas 1 Canada 1 China 171 Europe 1 France 3 Germany 3 India 10 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 1 United States 17 Global 211

Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Tel: 025-84430028 13815430202
Email: sale02@cqherb.com
Country: China
ProdList: 294
Advantage: 59

Xi'an Sunriver Biotech Ltd.

Tel: 13991954170
Email: info@sunriverbio.com
Country: China
ProdList: 183
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

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View Lastest Price from NARINGENIN manufacturers

Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.

Product: Naringenin 67604-48-2
Price: US $172.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 50kg
Release date: 2020-06-13

Baoji Guokang Healthchem co.,ltd

Product: NARINGENIN 67604-48-2
Price: US $80.00/kg/bag
Min. Order: 1公斤/袋
Purity: 98%
Supply Ability: 5000T
Release date: 2021-06-07

Zhuozhou Wenxi import and Export Co., Ltd

Product: (+/-)-Naringenin >=95% 67604-48-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-27

67604-48-2, NARINGENINRelated Search:

Prunin NARINGENIN CHALCONE Dihydromyricetin Naringenin Naringenin 7-O-β-D-Glucuronide (Mixture of Diastereomers) Naringenin trimethyl ether Naringin PHENETHYL FORMATE Phenethyl acetate 2-METHOXYACETOPHENONE Phenacyl acetate BENZYLOXYACETALDEHYDE 2,4-Dihydroxyacetophenone (+/-)-Naringenin 2-HYDROXYPHENETHYL ALCOHOL FEMA 2860 4-Hydroxyphenethyl alcohol ACETOXYACETONE

(+/-)-2,3-DIHYDRO-5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)-4H-1-BENZOPYRAN-4-ONE

TIMTEC-BB SBB006461

5,7,4'-TRIHYDROXYFLAVANONE

5,7-DIHYDROXY-2-(4-HYDROXYPHENYL)CHROMAN-4-ONE

4',5,7-Trihydroxyflavanone,97%

4H-1-Benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-

4μ,5,7-Trihydroxyflavanone, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

(±)-Naringenin, 4μ,5,7-Trihydroxyflavanone, (±)-2,3-Dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

2-(4-Hydroxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one

4',5,7-Trihydroxy-2,3-dihydroflavone

BE-14348A

(R,S)-Naringenin

rac Naringenin

(±)-Naringenin(Naringenin)

(+/-)-Naringenin >=95%

5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

Naringenin Standard

Naringenin Racemate

()-Naringenin

Potassium Channel,inhibit,(±)Naringenin,(±)-Naringenin,myocytes,vasorelaxant,(±) Naringenin,Inhibitor,KcsA

Naringenin-RM

(±)-Naringenin, Antioxidant

(±)-Naringenin, 10 mM in DMSO

(±)-Naringenin

D4-Naringenin

67604-48-2

Chemopreventive Agents

Cancer Research

BioChemical

Flavonoids

Enzyme Inhibitors

and Flavanols

Benzopyrans

Bioactive Small Molecules

Building Blocks

Cell Biology

Chemical Synthesis

Citrus aurantium (Seville orange)

Flavonols

Heterocyclic Building Blocks

N

Nutrition Research

Phytochemicals by Chemical Classification

Phytochemicals by Plant (Food/Spice/Herb)

Aromatics

Inhibitors

Intermediates & Fine Chemicals

Pharmaceuticals

Biochemistry

Flavonoids