ChemicalBook > CAS DataBase List > (+)-Biotin-PEG8-NHS Ester

(+)-Biotin-PEG8-NHS Ester

Product Name: (+)-Biotin-PEG8-NHS Ester
CAS No.: 2143968-03-8
Chemical Name: (+)-Biotin-PEG8-NHS Ester
Synonyms: Biotin-PEG8-SPA;(+)-Biotin-PEG8-NHS Ester;2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate;4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
CBNumber: CB83311639
Molecular Formula: C33H56N4O14S
Formula Weight: 764.88
MOL File: 2143968-03-8.mol

Less

(+)-Biotin-PEG8-NHS Ester Property

Density: 1.29±0.1 g/cm3(Predicted)
pka: 13.90±0.40(Predicted)
form: Solid
color: White to off-white

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

purepeg

Product number: 246908
Product name: (+)-Biotin-PEG8-NHSEster
Purity: min.95%
Packaging: 50mg
Price: $140
Updated: 2021/12/16

Less

(+)-Biotin-PEG8-NHS Ester Chemical Properties,Usage,Production

Uses

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Biotin-PEG8-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

(+)-Biotin-PEG8-NHS Ester Preparation Products And Raw materials

Raw materials

Preparation Products

Less

(+)-Biotin-PEG8-NHS Ester Suppliers

China 46 United Kingdom 1 United States 4 Global 51

Zhejiang Rui 'ao Biological Technology Co.,LTD.

Tel: +86-573-82087565 15757883359
Email: yan@ruiaochem.cn
Country: China
ProdList: 640
Advantage: 58

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Changzhou Hopschain Chemical Co.,Ltd.

Tel: 0519-85528066 13775048983
Fax: 0519-85528066
Email: sales@hopschem.com
Country: China
ProdList: 31553
Advantage: 55

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10109
Advantage: 58

Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 571-86101219 18768477782
Fax: -
Email: sales09@leobiochem.com
Country: China
ProdList: 433
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9721
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Wuhan Borenpharm Co., Ltd

Tel: 027-65563561 18717150066
Fax: 027-59218822
Email: 3207347307@qq.com
Country: CHINA
ProdList: 1238
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1994
Advantage: 58

Shanghai Jiange Chemical Co., Ltd.

Tel: 15921040873
Email: 1434142450@qq.com
Country: CHINA
ProdList: 7649
Advantage: 58

Shaanxi borno biotechnology co., LTD

Tel: +86-13759708231
Email: asherw9@hotmail.com
Country: China
ProdList: 2373
Advantage: 58

Zhengzhou anmousse chemical products co. LTD

Tel: 0371-55289822 18737195735
Fax: QQ:483339295
Email: 483339295@qq.com
Country: China
ProdList: 7587
Advantage: 58

Nanjing chengqimei Biotechnology Co., Ltd

Tel: 19850819832
Email: 2173594524@qq.com
Country: China
ProdList: 2638
Advantage: 58

Guangzhou Hongyuan Chemical Co.,Ltd

Tel: 15817493340
Email: 981810490@qq.com
Country: China
ProdList: 1566
Advantage: 58

TCI (Shanghai) Chemical Trading Co., Ltd.

Tel: 021-61109150
Fax: 021-61105897
Email: sales@tcisct.com
Country: China
ProdList: 29668
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 15801484223;
Email: psaitong@jm-bio.com
Country: China
ProdList: 29757
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-1647117 13681763483
Email: product02@bidepharm.com
Country: China
ProdList: 59936
Advantage: 58

Xi'an Qiyue Biotechnology Co., Ltd.

Tel: 400-400-6966-012-012 17778955912
Email: 2957605606@qq.com
Country: China
ProdList: 2535
Advantage: 58

Affinity（Wuhan）Ltd.

Tel: 15841022315
Email: sales@affinitytech.cn
Country: China
ProdList: 3000
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 5061
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18921922613
Email: hywu@aikonchem.com
Country: China
ProdList: 10709
Advantage: 58

Henan Weitixi Chemical Technology Co., Ltd

Tel: 0371-53370800 18037197114
Email: 2853031799@qq.com
Country: China
ProdList: 9881
Advantage: 58

Vicbio Biotechnology Co., Ltd.

Tel: 400-001-2615 13691409741
Email: info@vicbio.com
Country: China
ProdList: 4434
Advantage: 58

Shanghai Haohong Scientific Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 40000
Advantage: 58

Shanghai Easy CDMO Co.,Ltd

Tel: 021-61734564 13854185395;
Email: info@easycdmo.com
Country: China
ProdList: 10024
Advantage: 58

Shandong fen Boyu Biotechnology Co.,LTD

Tel: 13356310019 13356310019;
Email: boyu2024@163.com
Country: China
ProdList: 3247
Advantage: 58

Chengdu Hanwei Biotechnology Co., Ltd

Tel: 17360178904 18217049878
Email: zengzongwen@pegtide.com
Country: China
ProdList: 1222
Advantage: 58

Changsha Morning Shine Co., Ltd.

Tel: 189-75832125 13397510867
Email: BD@csmspharm.com
Country: China
ProdList: 399
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: 18143011203
Email: ET-market@chemextension.com
Country: China
ProdList: 32048
Advantage: 58

TargetMol Chemicals Inc.

Tel: 15002134094
Email: marketing@targetmol.cn
Country: China
ProdList: 29257
Advantage: 58

Shanghai Yanfen Biochemical Technology Co.,LTD

Tel: 17721070236 15002190549;
Email: yanfen2023@126.com
Country: China
ProdList: 1837
Advantage: 58

Shandong Dongde New Materials Co., Ltd

Tel: 15666167041
Email: 15666167041@163.com
Country: China
ProdList: 2983
Advantage: 58

Wanxin Biotechnology (Jiaxing) Co., LTD

Tel: 0573-83568680 18057391398
Email: 3956524501@qq.com
Country: China
ProdList: 1442
Advantage: 58

Shanghai Titan Scientific Co.,Ltd

Tel: 16621234537
Email: chenyj@titansci.com
Country: China
ProdList: 10000
Advantage: 58

Henan Mengtai Pharmaceutical Technology Co., Ltd

Tel: 176345344 7 17634854698
Email: 1959525201@qq.com
Country: China
ProdList: 10000
Advantage: 58

Biosynth Biological Technology (Suzhou) Co Ltd

Tel: 51288865780
Email: sales@biosynth.com
Country: China
ProdList: 6051
Advantage: 58

Santa Cruz Biotechnology Inc

Tel: 021-60936350
Email: scbt@scbt.com
Country: China
ProdList: 6594
Advantage: 58

Wuhan Xinsengyang Biotechnology Co., Ltd

Tel: 18402740988 18402740988
Email: 3879363529@qq.com
Country: China
ProdList: 449
Advantage: 58

Changsha Morning Shine Co., Ltd.

Tel: +8613751227286
Email: chenkaijie@csmspharm.com
Country: China
ProdList: 300
Advantage: 58

Xian confluore Biological Technology Co., Ltd.

Tel: +86-15680926068
Email: 1924344760@confluore.cn
Country: China
ProdList: 2997
Advantage: 58

Jilin Chinese Academy of Sciences-yanshen Technology

Tel: +undefined18143011203
Email: info@chemextension.com
Country: China
ProdList: 42056
Advantage: 58

Hangzhou MolCore BioPharmatech Co.,Ltd.

Tel: +86-057181025280; +8617767106207
Fax: 0571-85806285
Email: sales@molcore.com
Country: China
ProdList: 49734
Advantage: 58

Shanghai Hao Zhun Biological Technology Co., Ltd.

Tel: --
Fax: --
Email: info@zzsrm.com
Country: CHINA
ProdList: 6650
Advantage: 58

Less

View Lastest Price from (+)-Biotin-PEG8-NHS Ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-PEG8-NHS ester 2143968-03-8
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-30

2143968-03-8, (+)-Biotin-PEG8-NHS EsterRelated Search:

Biotin-PEG8-SH Biotin-PEG8-Mal Biotin-PEG8-acid Biotin-PEG8-hydrazide (+)-Biotin-PEG8-CH2CH2NH2 Biotin-PEG8-alcohol Biotin-PEG8-oxyamine HCl salt Biotin-PEG8-TFP Biotin-PEG8-azide Biotin-PEG7-Amine Biotin-PEG6-t-butyl ester Biotinoyl tripeptide-1 Biotin-PEG4-S-S-NHS Biotin-PEG3-t-butyl ester INDEX NAME NOT YET ASSIGNED BIOTIN HYDRAZIDE Biotin-PEG7-thiourea Biotin-SS-Amine HCl Salt

(+)-Biotin-PEG8-NHS Ester

Biotin-PEG8-SPA

4,7,10,13,16,19,22,25-Octaoxa-28-azatritriacontanoic acid, 33-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-29-oxo-, 2,5-dioxo-1-pyrrolidinyl ester

2,5-Dioxopyrrolidin-1-yl 29-oxo-33-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-4,7,10,13,16,19,22,25-octaoxa-28-azatritriacontanoate

2143968-03-8

SiChem

peg

Biotin