2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER

Product Name: 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER
CAS No.: 660867-80-1
Chemical Name: 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER
Synonyms: CAS:660867-80-1;2-Methylpyridine-4-;2-aMino-4-pyridine boronic ester;2-Picoline-4-boronic acid pinacolate;2-Picoline-4-boronic acid pinacol ester;2-Methylpyridine-4-boronic acid pinacol;2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER;2-Methyl-4-pyridineboronic acid pinacol ester;2-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine;2-(2-Methyl-4-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
CBNumber: CB8332208
Molecular Formula: C12H18BNO2
Formula Weight: 219.09
MOL File: 660867-80-1.mol

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2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER Property

Melting point:: 66-71°C
Boiling point:: 315.9±30.0 °C(Predicted)
Density: 1.02
storage temp.: Inert atmosphere,Store in freezer, under -20°C
solubility: soluble in Methanol
form: powder to crystal
pka: 5.11±0.10(Predicted)
color: White to Almost white

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Safety

Hazard Codes: Xi
Risk Statements: 37/38-41
Safety Statements: 26-39
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS007583
Product name: 2-methylpyridine-4-boronic acid pinacol ester
Purity: Aldrich<SUP>CPR</SUP>
Packaging: 500 mg
Price: $107
Updated: 2025/07/31

TCI Chemical

Product number: M2867
Product name: 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity: >98.0%(T)
Packaging: 1g
Price: $146
Updated: 2025/07/31

TCI Chemical

Product number: M2867
Product name: 2-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
Purity: >98.0%(T)
Packaging: 5g
Price: $583
Updated: 2025/07/31

ChemScene

Product number: CS-W000958
Product name: 2-Methylpyridine-4-boronicacidpinacolester
Packaging: 1g
Price: $36
Updated: 2021/12/16

Apolloscientific

Product number: OR42154
Product name: 2-Methylpyridine-4-boronicacid,pinacolester
Packaging: 1g
Price: $40
Updated: 2021/12/16

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2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER Chemical Properties,Usage,Production

Synthesis

22282-99-1

73183-34-3

660867-80-1

The general procedure for the synthesis of 2-methyl-4-pyridylboronic acid pinacol ester from 4-bromo-2-methylpyridine (0.500 g, 2.906 mmol) and pinacol ester of bis(diphenylphosphine) (0.812 g, 3.997 mmol) is as follows: in an inert atmosphere, 4-bromo-2-methylpyridine, pinacol ester of bis(boronic acid), potassium acetate (0.854 g, 8.720 mmol) and [1,1'-bis(diphenylphosphino)ferrocene]palladium(II) dichloride (0.021 g, 0.029 mmol) were dissolved in degassed 1,4-dioxane (5 mL) in a 50 mL sealed tube. The reaction mixture was stirred at 80 °C for 4 hours. Upon completion of the reaction, the solvent was removed by rotary evaporation and the crude product was purified by silica gel column chromatography (eluent: ethyl acetate/ether = 30:70) to afford 2-methyl-4-pyridinylboronic acid pinacol ester (0.250 g, 39% yield) as an off-white solid. m/z 220.1 [M + H]+ was shown by LCMS analysis.

References

[1] Patent: WO2014/111871, 2014, A1. Location in patent: Page/Page column 199
[2] Patent: WO2004/14913, 2004, A2. Location in patent: Page 82
[3] Patent: US2011/190269, 2011, A1. Location in patent: Page/Page column 36
[4] Patent: WO2011/92272, 2011, A1. Location in patent: Page/Page column 73
[5] Patent: WO2011/119518, 2011, A1. Location in patent: Page/Page column 47-48

2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER Suppliers

Americas 1 China 147 Europe 1 France 1 Germany 1 India 3 Japan 1 United Kingdom 2 United States 16 Global 173

Accela ChemBio Inc.

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View Lastest Price from 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER manufacturers

Henan Fengda Chemical Co., Ltd

Product: 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 660867-80-1
Price: US $36.00-1.10/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

Dideu Industries Group Limited

Product: 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 660867-80-1
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-08-26

Career Henan Chemical Co

Product: 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER 660867-80-1
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-13

660867-80-1, 2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTERRelated Search:

2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER

2-METHYL-4-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE

2-Picoline-4-boronic acid pinacol ester

2-Picoline-4-boronic acid pinacolate

2-Methyl-4-pyridineboronic acid pinacol ester

2-Methylpyridine-4-boronic acid pinacol

2-Methylpyridine-4-boronic acid pinacol ester, 95%, May contain up to 3% water

2-aMino-4-pyridine boronic ester

2-Methylpyridine-4-

Pyridine, 2-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

2-(2-Methyl-4-pyridyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-METHYLPYRIDINE-4-BORONIC ACID PINACOL ESTER ISO 9001：2015 REACH

2-methyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

CAS:660867-80-1

660867-80-1

660876-80-1

Organic boronic acid

Boronic ester

Organoborons

Pyridine