Autophinib

Product Name: Autophinib
CAS No.: 1644443-47-9
Chemical Name: Autophinib
Synonyms: CS-2834;Autophinib;PI3K,inhibit,Autophagy,Autophinib,Phosphoinositide 3-kinase,Inhibitor;6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-pyrimidinamine;6-CHLORO-N-(5-METHYL-1H-PYRAZOL-3-YL)-2-(4-NITROPHENOXY)PYRIMIDIN-4-AMINE;4-Pyrimidinamine, 6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-
CBNumber: CB83344886
Molecular Formula: C14H11ClN6O3
Formula Weight: 346.73
MOL File: 1644443-47-9.mol

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Autophinib Property

Boiling point:: 640.6±65.0 °C(Predicted)
Density: 1.547±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility: DMSO:13.98(Max Conc. mg/mL);40.32(Max Conc. mM)
form: A solid
pka: 13.78±0.10(Predicted)
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML2632
Product name: Autophinib
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $89.3
Updated: 2022/05/15

Sigma-Aldrich

Product number: SML2632
Product name: Autophinib
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $361
Updated: 2022/05/15

Cayman Chemical

Product number: 27320
Product name: Autophinib
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 27320
Product name: Autophinib
Packaging: 25mg
Price: $494
Updated: 2024/03/01

Cayman Chemical

Product number: 27320
Product name: Autophinib
Packaging: 5mg
Price: $139
Updated: 2024/03/01

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Autophinib Chemical Properties,Usage,Production

Uses

Autophinib is a potent VPS34 inhibitor (IC50 = 19 nM). Inhibits starvation- and Rapamycin-induced autophagy (IC50 values = 40 and 90 nM, respectively).

storage

Store at +4°C

Autophinib Preparation Products And Raw materials

Raw materials

Preparation Products

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Autophinib Suppliers

China 55 India 1 United Kingdom 1 United States 10 Global 67

Tocris Bioscience

Tel: --
Fax: --
Email: customerservice@tocris.co.uk
Country: United Kingdom
ProdList: 5726
Advantage: 77

1644443-47-9, AutophinibRelated Search:

N,N'-Ethylenebis(stearamide) Deionized water (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride

Autophinib

6-CHLORO-N-(5-METHYL-1H-PYRAZOL-3-YL)-2-(4-NITROPHENOXY)PYRIMIDIN-4-AMINE

6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-pyrimidinamine

CS-2834

4-Pyrimidinamine, 6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-

PI3K,inhibit,Autophagy,Autophinib,Phosphoinositide 3-kinase,Inhibitor

1644443-47-9