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Autophinib

Product Name
Autophinib
CAS No.
1644443-47-9
Chemical Name
Autophinib
Synonyms
CS-2834;Autophinib;PI3K,inhibit,Autophagy,Autophinib,Phosphoinositide 3-kinase,Inhibitor;6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-pyrimidinamine;6-CHLORO-N-(5-METHYL-1H-PYRAZOL-3-YL)-2-(4-NITROPHENOXY)PYRIMIDIN-4-AMINE;4-Pyrimidinamine, 6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-
CBNumber
CB83344886
Molecular Formula
C14H11ClN6O3
Formula Weight
346.73
MOL File
1644443-47-9.mol
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Autophinib Property

Boiling point:
640.6±65.0 °C(Predicted)
Density 
1.547±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
DMSO:13.98(Max Conc. mg/mL);40.32(Max Conc. mM)
form 
A solid
pka
13.78±0.10(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2632
Product name
Autophinib
Purity
≥98% (HPLC)
Packaging
5MG
Price
$89.3
Updated
2022/05/15
Sigma-Aldrich
Product number
SML2632
Product name
Autophinib
Purity
≥98% (HPLC)
Packaging
25MG
Price
$361
Updated
2022/05/15
Cayman Chemical
Product number
27320
Product name
Autophinib
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
27320
Product name
Autophinib
Packaging
25mg
Price
$494
Updated
2024/03/01
Cayman Chemical
Product number
27320
Product name
Autophinib
Packaging
5mg
Price
$139
Updated
2024/03/01
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Autophinib Chemical Properties,Usage,Production

Uses

Autophinib is a potent VPS34 inhibitor (IC50 = 19 nM). Inhibits starvation- and Rapamycin-induced autophagy (IC50 values = 40 and 90 nM, respectively).

storage

Store at +4°C

Autophinib Preparation Products And Raw materials

Raw materials

Preparation Products

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Autophinib Suppliers

China 55 India 1 United Kingdom 1 United States 10 Global 67
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14055
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
InvivoChem
Tel
+1-708-310-1919 +1-13798911105
Fax
708-557-7486
Email
sales@invivochem.cn
Country
United States
ProdList
6391
Advantage
58
Cckinase, Inc.
Tel
+1 (732)236-3202
Email
sales@cckinase.com
Country
United States
ProdList
2738
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81
MedChemExpress
Tel
--
Fax
--
Email
sales@medchemexpress.com
Country
United States
ProdList
6398
Advantage
58
Axon Medchem LLC
Tel
--
Fax
--
Email
info@axonmedchem.com
Country
United States
ProdList
763
Advantage
58

1644443-47-9, AutophinibRelated Search:

N,N'-Ethylenebis(stearamide) Deionized water (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride

  • Autophinib
  • 6-CHLORO-N-(5-METHYL-1H-PYRAZOL-3-YL)-2-(4-NITROPHENOXY)PYRIMIDIN-4-AMINE
  • 6-Chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-pyrimidinamine
  • CS-2834
  • 4-Pyrimidinamine, 6-chloro-N-(5-methyl-1H-pyrazol-3-yl)-2-(4-nitrophenoxy)-
  • PI3K,inhibit,Autophagy,Autophinib,Phosphoinositide 3-kinase,Inhibitor
  • 1644443-47-9