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Biotin-PEG3-CH2COOH

Product Name
Biotin-PEG3-CH2COOH
CAS No.
1189560-96-0
Chemical Name
Biotin-PEG3-CH2COOH
Synonyms
CAS_1189560-96-0;Biotin-PEG3-CH2COOH;Biotin-PEG?-CH?COOH;Biotin-PEG3-acetic Acid;11-(Biotinamido)-3,6,9-trioxaundecanoic Acid;13-oxo-17-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecanoic acid;3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-;13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecan-1-oic acid;2-{2-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]ethoxy}acetic acid;Biotin-PEG3-CH2COOH/3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-
CBNumber
CB83354304
Molecular Formula
C18H31N3O7S
Formula Weight
433.52
MOL File
1189560-96-0.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
B5711
Product name
Biotin-PEG3-acetic Acid
Packaging
50MG
Price
$437
Updated
2025/07/31
Acrotein
Product number
B-1365
Product name
Biotin-PEG3-CH2COOH
Purity
97%
Packaging
0.5g
Price
$366.7
Updated
2021/12/16
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Biotin-PEG3-CH2COOH Chemical Properties,Usage,Production

Uses

Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Biological Activity

Biotin-PEG3-CH2COOH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Biotin-PEG3-CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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Biotin-PEG3-CH2COOH Suppliers

TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
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03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
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28387
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TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
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23671
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Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
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China
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5872
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Shanghai Macklin Biochemical Co.,Ltd.
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15221275939
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021-50706099
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shenlinxing@macklin.cn
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China
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15873
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Taizhou GreenChem Pharmaceutical Co., Ltd.
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0514-86654616 15366892466
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greenchem@tzglmk.com
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China
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Borenpharm Co., Ltd
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027-65563561
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86-27-59218822
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sales@borenpharm.com
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
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China
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71826
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Zhengzhou Acme Chemical Co., Ltd.
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0371-0371-55629727 13323845623
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037155629727
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2885676761@qq.com
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China
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Amatek Scientific Co. Ltd.
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0512-56316828
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0512-56316826
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info@amateksci.com
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China
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28785
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SHANGHAI FDC-CHEMICAL CO.,LTD
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021-61469567 13482353728
Fax
021-61161605
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sales@fdc-chemical.com
Country
China
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1189560-96-0, Biotin-PEG3-CH2COOHRelated Search:


  • Biotin-PEG3-acetic Acid
  • 13-oxo-17-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecanoic acid
  • Biotin-PEG3-CH2COOH
  • CAS_1189560-96-0
  • 3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-
  • 11-(Biotinamido)-3,6,9-trioxaundecanoic Acid
  • 13-oxo-17-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-3,6,9-trioxa-12-azaheptadecan-1-oic acid
  • Biotin-PEG3-CH2COOH/3,6,9-Trioxa-12-azaheptadecanoic acid, 17-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-13-oxo-
  • Biotin-PEG?-CH?COOH
  • 2-{2-[2-(2-{5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanamido}ethoxy)ethoxy]ethoxy}acetic acid
  • 1189560-96-0
  • peg