N-Mal-N-bis(PEG4-NHS ester)

Product Name: N-Mal-N-bis(PEG4-NHS ester)
CAS No.: 2112738-60-8
Chemical Name: N-Mal-N-bis(PEG4-NHS ester)
Synonyms: N-Mal-N-bis(PEG4-NHS ester);Bis(2,5-dioxopyrrolidin-1-yl) 16-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontane-1,31-dioate;4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-, 1,31-bis(2,5-dioxo-1-pyrrolidinyl) ester
CBNumber: CB83373747
Molecular Formula: C37H54N4O19
Formula Weight: 858.84
MOL File: 2112738-60-8.mol

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N-Mal-N-bis(PEG4-NHS ester) Property

Boiling point:: 892.3±75.0 °C(Predicted)
Density: 1.37±0.1 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: -0.93±0.70(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23736
Product name: N-Mal-N-bis(PEG4-NHSester)
Purity: 98%
Packaging: 50mg
Price: $540
Updated: 2021/12/16

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N-Mal-N-bis(PEG4-NHS ester) Chemical Properties,Usage,Production

Description

N-Mal-N-bis(PEG4-NHS ester) is a branched maleimide linker with two terminal NHS esters. NHS esters is used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule.

Uses

N-Mal-N-bis(PEG4-NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-Mal-N-bis(PEG4-NHS ester) Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-Mal-N-bis(PEG4-NHS ester) manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N-Mal-N-bis(PEG4-NHS ester) 2112738-60-8
Price: US $0.00/mg
Min. Order: 250mg
Purity: >95.00%
Supply Ability: 250mg
Release date: 2024-03-28

2112738-60-8, N-Mal-N-bis(PEG4-NHS ester)Related Search:

Bis(2,5-dioxopyrrolidin-1-yl) (disulfanediylbis(ethane-2,1-diyl)) dicarbonate alpha, oMega-DisucciniMidyl triethylene glycol Bis(NHS)PEG5 N-Mal-N-bis(PEG2-NHS ester) N-Mal-N-bis(PEG4-NH-Boc) N-Mal-N-bis(PEG2-NH-Boc) N-Mal-N-bis(PEG2-t-butyl ester) Bis-N-succinimidyl diglycolic acid, 2,2-Oxydiacetic acid bis-N-succinimidyl ester Bis-peg13-nhs ester INDEX NAME NOT YET ASSIGNED Bis-PEG6-NHS ester Bis-PEG1-NHS ester

N-Mal-N-bis(PEG4-NHS ester)

4,7,10,13,19,22,25,28-Octaoxa-16-azahentriacontanedioic acid, 16-[3-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]-, 1,31-bis(2,5-dioxo-1-pyrrolidinyl) ester

Bis(2,5-dioxopyrrolidin-1-yl) 16-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanoyl)-4,7,10,13,19,22,25,28-octaoxa-16-azahentriacontane-1,31-dioate

2112738-60-8

C37H54N4O19