NS 1619

Product Name: NS 1619
CAS No.: 153587-01-0
Chemical Name: NS 1619
Synonyms: NS 161;NS 1619;NS1619;NS 1619;NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN;1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b;1-(2-Hydroxy-5-(Trifluoromethyl)Phenyl)-5-(Trifluoromethyl)-1H-Benzo[D]Imidazol-2-Ol;1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one;1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE;1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one;2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-
CBNumber: CB8359809
Molecular Formula: C15H8F6N2O2
Formula Weight: 362.23
MOL File: 153587-01-0.mol

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NS 1619 Property

Density: 1.563±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.47 mg/mL
pka: 8.32±0.48(Predicted)
form: solid
color: white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N170
Product name: NS 1619
Purity: powder
Packaging: 5mg
Price: $180
Updated: 2024/03/01

Sigma-Aldrich

Product number: N170
Product name: NS 1619
Purity: powder
Packaging: 25mg
Price: $645
Updated: 2024/03/01

Cayman Chemical

Product number: 18876
Product name: NS 1619
Purity: ≥98%
Packaging: 1mg
Price: $37
Updated: 2024/03/01

Cayman Chemical

Product number: 18876
Product name: NS 1619
Purity: ≥98%
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 18876
Product name: NS 1619
Purity: ≥98%
Packaging: 10mg
Price: $142
Updated: 2024/03/01

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NS 1619 Chemical Properties,Usage,Production

Uses

NS 1619 is a large conductance calcium-activated potassium channels (BKCa) activator and has been shown to induce precondition in the heart.

Definition

ChEBI: A member of the class of benzimidazoles that is 1,3-dihydro-2H-benzimidazol-2-one in which the hydrogens at positions 1 and 5 are replaced are replaced by 2-hydroxy-5-(trifluoromethyl)phenyl and trifluoromethyl groups, respectively. It i an opener/activator of the large-conductance calcium-activated potassium channel (Bkca).

Biochem/physiol Actions

NS 1619 is a selective large conductance Ca2+-activated K+-channel activator. The compound is known for its vasodilating and anti-proliferative properties. It is studied that NS 1619 can protect cardiac muscle against ischemia and reperfusion injury.

storage

+4°C

NS 1619 Preparation Products And Raw materials

Raw materials

Preparation Products

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NS 1619 Suppliers

China 71 Europe 1 India 2 Japan 1 Switzerland 1 United Kingdom 4 United States 17 Global 97

EMMX Biotechnology LLC

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Musechem

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TargetMol Chemicals Inc.

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RR Scientific LLC

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InvivoChem

Tel: +1-708-310-1919 +1-13798911105
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Alchem Pharmtech,Inc.

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Aladdin Scientific

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TargetMol Chemicals Inc.

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Matrix Scientific

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3B Scientific Corporation

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BIOMOL INTERNATIONAL, LP

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View Lastest Price from NS 1619 manufacturers

Career Henan Chemical Co

Product: NS 1619 153587-01-0
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-13

153587-01-0, NS 1619Related Search:

Glibenclamide Nicorandil CHARYBDOTOXIN NS-6180 Adenosine 5'-[γ-thio]triphosphate TetralithiuM Salt APAMIN PENITREM A NS1643 PNU 37883 hydrochloride TRAM-34 5-HYDROXYDECANOIC ACID SODIUM SALT CLOFILIUM TOSYLATE Gabapentin-lactam PAXILLINE 2-amino-1-(4-chlorobenzyl)-5-trifluoromethylbenzimidazole NS 11394 Selexipag N-(4-PHENYLSULFONYLPHENYL)-3,3,3-TRIFLUORO-2-HYDROXY-2-METHYLPROPANAMIDE

NS 1619

NS 1619 (1,3-DIHYDRO-1-(2-HYDROXY-5-(TRI FLUOROMETHYL)PHEN

1,3-DIHYDRO-1-[2-HYDROXY-5-(TRIFLUOROMETHYL)PHENYL]-5-(TRIFLUOROMETHYL)-2H-BENZIMIDAZOL-2-ONE

1-(2-hydroxy-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-1H-benzo[d]imidazol-2(3H)-one

1-(2-hydroxy-5-(trifluoroMethyl)phenyl)-5-(trifluoroMethyl)-1H-b

NS1619;NS 1619

NS 161

2H-Benzimidazol-2-one, 1,3-dihydro-1-[2-hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-

1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzimidazol-2-one

1-[2-Hydroxy-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one

1-(2-Hydroxy-5-(Trifluoromethyl)Phenyl)-5-(Trifluoromethyl)-1H-Benzo[D]Imidazol-2-Ol

153587-01-0

C15H8F6N2O2

Monovalent Ion Channels

Ion Channels

Voltage-gated Ion Channels

Potassium Channel Modulators

Cell Signaling and Neuroscience

Cell Biology

BioChemical

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