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VITAMIN E NICOTINATE

Product Name
VITAMIN E NICOTINATE
CAS No.
43119-47-7
Chemical Name
VITAMIN E NICOTINATE
Synonyms
renascin;Ve Nicotinate;VitaminEnicotihat;VITAMIN E NICOTITE;Vitamin E nicotinate;tocopherylnicotinate;vitaminenicotinicacidester;ALPHA-TOCOPHERYL NICOTINATE;D-alpha-Tocopheryl nicotinate;VITAMIN E NICOTINATE USP/EP/BP
CBNumber
CB8381817
Molecular Formula
C35H53NO3
Formula Weight
535.8
MOL File
43119-47-7.mol
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VITAMIN E NICOTINATE Property

Boiling point:
649.0±55.0 °C(Predicted)
Density 
0.990±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
pka
3.03±0.10(Predicted)
Cosmetics Ingredients Functions
SKIN PROTECTING
SKIN CONDITIONING
ANTIOXIDANT
LogP
11.327 (est)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Matrix Scientific
Product number
094191
Product name
(R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl nicotinate
Purity
95+%
Packaging
250mg
Price
$288
Updated
2021/12/16
Matrix Scientific
Product number
094191
Product name
(R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl nicotinate
Purity
95+%
Packaging
1g
Price
$639
Updated
2021/12/16
Chemenu
Product number
CM133262
Product name
(R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ylnicotinate
Purity
95%
Packaging
1g
Price
$355
Updated
2021/12/16
Crysdot
Product number
CD11124671
Product name
(R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ylnicotinate
Purity
95+%
Packaging
1g
Price
$380
Updated
2021/12/16
Alichem
Product number
43119477
Product name
(R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ylnicotinate
Packaging
1g
Price
$414.2
Updated
2021/12/16
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VITAMIN E NICOTINATE Chemical Properties,Usage,Production

Uses

Vitamin E nicotinate is the derivative of Vitamin E. Vitamin E nicotinate exhibits antioxidant activity and prevents lipid peroxidation. Vitamin E nicotinate upregulates levels of CD4+ T cells and IL-2, exhibits immunomodulatory activity. Vitamin E nicotinate exhibits antiplatelet and antihypertensive activities, that can be used in atherosclerosis and thrombosis ressearch[1].

Definition

ChEBI: Tocopheryl nicotinate is a tocol.

Synthesis

To a three-necked flask add 250g of dichloromethane, add 50g of nicotinic acid, 43.9g of N,N'-carbonyl diimidazole, 30 ?? C reaction for 2 hours, take 122.5g of tocopherol dissolved in 150g of dichloromethane, and then dropwise added to the reaction system, dropwise, 35 ?? C reaction for 4 hours, and then wash with water and saturated aqueous sodium bicarbonate, respectively, separate out the Organic layer, recovery of dichloromethane under reduced pressure, concentrated to dry, add anhydrous ethanol crystallization, filtration, drying to get the refined product, that is, VE nicotinic acid ester 137g, yield 90%, product HPLC purity 99.6%.

References

[1] Duncan KR, et al., Vitamin E Nicotinate. Antioxidants (Basel). 2017 Mar 13;6(1):20. DOI:10.3390/antiox6010020

VITAMIN E NICOTINATE Preparation Products And Raw materials

Raw materials

Preparation Products

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VITAMIN E NICOTINATE Suppliers

Shandong Xiya Chemical Co., Ltd
Tel
13355009207 13355009207
Fax
0539-6365991
Email
3007715519@qq.com
Country
China
ProdList
18729
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7811
Advantage
57
Shanghai Crmedicine Technology Co., Ltd.
Tel
021-60875190 60875209 607 609
Fax
021-60875190-601
Email
win006@chinamaking.com.cn
Country
China
ProdList
12
Advantage
62
Shanghai CoachChem Co., Ltd.
Tel
+86-21-67299971;+86-21-67290723 18117322963
Fax
021-67299972
Email
marketing@coachchem.com
Country
China
ProdList
91
Advantage
62
Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
Advantage
52
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
ShangHai Zexin Chemical Technology Co., Ltd.
Tel
021-60136491 15901897992
Fax
021-60136492
Country
China
ProdList
455
Advantage
55
Chengdu HuaXia Chemical Reagent Co. Ltd
Tel
400-1166-196 13458535857
Fax
QQ:800101999
Email
cdhxsj@163.com
Country
China
ProdList
13350
Advantage
58
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14917
Advantage
59
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
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View Lastest Price from VITAMIN E NICOTINATE manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
vitamin e nicotinate 43119-47-7
Price
US $13.69/Kg/Bag
Min. Order
100g/Bag
Purity
98%
Supply Ability
300tons
Release date
2021-12-20
Dideu Industries Group Limited
Product
VITAMIN E NICOTINATE 43119-47-7
Price
US $1.10/g
Min. Order
1g
Purity
99.9%
Supply Ability
100 Tons min
Release date
2021-07-30
Career Henan Chemical Co
Product
VITAMIN E NICOTINATE 43119-47-7
Price
US $1.00/KG
Min. Order
1KG
Purity
98%-99.9%
Supply Ability
200kg
Release date
2020-01-12

43119-47-7, VITAMIN E NICOTINATERelated Search:


  • vitaminenicotinicacidester
  • ALPHA-TOCOPHERYL NICOTINATE
  • (+/-)-2,5,7,8-tetramethyl-2-(4,8,12 (-trimethyltridecyl)chromanol nicotinate
  • [2r*(4r*,8r*)]-(+/-)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-yl nicotinate
  • Ve Nicotinate
  • 3-Pyridinecarboxylic acid, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-(4R,8R)-4,8,12-trimethyltridecyl-2H-1-benzopyran-6-yl ester
  • 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- benzopyran-6-yl ester, [2R-[2R*(3-Pyridinecarboxylic acid
  • 3-Pyridinecarboxylic acid, 3,4-dihydro-2,5,7,8-tetramethyl- 2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran -6-yl ester, [2R-[2R(4R,8R)]]-
  • VITAMIN E NICOTINATE (TOCOTHERYL NICOTINATE)
  • (R)-2,5,7,8-Tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-ol nicotinate
  • 5,7,8-Trimethyltocol nicotinate
  • Nicotinic acid (R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydro-2H-1-benzopyran-6-yl ester
  • [2R-[2R*(4R*,8R*)]]-3,4-Dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl nicotinate
  • Vitamin E nicotinate
  • tocopherylnicotinate
  • VitaminEnicotihat
  • (2r-(2r*(4r*,8r*)))-ridecyl)-2h-1-benzopyran-6-yleste
  • [2theta-[2theta(4theta,8theta)]]-ridecyl)-2h-1-benzopyran-6-yleste
  • 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-ylester,(2r-(2r*(4r3-pyridinecarboxylicaci
  • 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-ylester,[2R-[2R*(3-Pyridinecarboxylicacid
  • 3-pyridinecarboxylicacid,3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethylt
  • renascin
  • [2,5,7,8-TETRAMETHYL-2-(4,8,12-TRIMETHYLTRIDECYL)CHROMAN-6-YL] PYRIDINE-3-CARBOXYLATE
  • VITAMIN E NICOTINATE USP/EP/BP
  • D-alpha-Tocopheryl nicotinate
  • VITAMIN E NICOTITE
  • 43119-47-7
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