VITAMIN E NICOTINATE
- Product Name
- VITAMIN E NICOTINATE
- CAS No.
- 43119-47-7
- Chemical Name
- VITAMIN E NICOTINATE
- Synonyms
- renascin;Ve Nicotinate;VitaminEnicotihat;VITAMIN E NICOTITE;Vitamin E nicotinate;tocopherylnicotinate;vitaminenicotinicacidester;ALPHA-TOCOPHERYL NICOTINATE;D-alpha-Tocopheryl nicotinate;VITAMIN E NICOTINATE USP/EP/BP
- CBNumber
- CB8381817
- Molecular Formula
- C35H53NO3
- Formula Weight
- 535.8
- MOL File
- 43119-47-7.mol
VITAMIN E NICOTINATE Property
- Boiling point:
- 649.0±55.0 °C(Predicted)
- Density
- 0.990±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- pka
- 3.03±0.10(Predicted)
- Cosmetics Ingredients Functions
- SKIN PROTECTING
SKIN CONDITIONING
ANTIOXIDANT - LogP
- 11.327 (est)
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- 094191
- Product name
- (R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl nicotinate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $288
- Updated
- 2021/12/16
- Product number
- 094191
- Product name
- (R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-yl nicotinate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $639
- Updated
- 2021/12/16
- Product number
- CM133262
- Product name
- (R)-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ylnicotinate
- Purity
- 95%
- Packaging
- 1g
- Price
- $355
- Updated
- 2021/12/16
- Product number
- CD11124671
- Product name
- (R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ylnicotinate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $380
- Updated
- 2021/12/16
- Product number
- 43119477
- Product name
- (R)-2,5,7,8-Tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)chroman-6-ylnicotinate
- Packaging
- 1g
- Price
- $414.2
- Updated
- 2021/12/16
VITAMIN E NICOTINATE Chemical Properties,Usage,Production
Uses
Vitamin E nicotinate is the derivative of Vitamin E. Vitamin E nicotinate exhibits antioxidant activity and prevents lipid peroxidation. Vitamin E nicotinate upregulates levels of CD4+ T cells and IL-2, exhibits immunomodulatory activity. Vitamin E nicotinate exhibits antiplatelet and antihypertensive activities, that can be used in atherosclerosis and thrombosis ressearch[1].
Definition
ChEBI: Tocopheryl nicotinate is a tocol.
Synthesis
To a three-necked flask add 250g of dichloromethane, add 50g of nicotinic acid, 43.9g of N,N'-carbonyl diimidazole, 30 ?? C reaction for 2 hours, take 122.5g of tocopherol dissolved in 150g of dichloromethane, and then dropwise added to the reaction system, dropwise, 35 ?? C reaction for 4 hours, and then wash with water and saturated aqueous sodium bicarbonate, respectively, separate out the Organic layer, recovery of dichloromethane under reduced pressure, concentrated to dry, add anhydrous ethanol crystallization, filtration, drying to get the refined product, that is, VE nicotinic acid ester 137g, yield 90%, product HPLC purity 99.6%.
References
[1] Duncan KR, et al., Vitamin E Nicotinate. Antioxidants (Basel). 2017 Mar 13;6(1):20. DOI:10.3390/antiox6010020
VITAMIN E NICOTINATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from VITAMIN E NICOTINATE manufacturers
- Product
- vitamin e nicotinate 43119-47-7
- Price
- US $13.69/Kg/Bag
- Min. Order
- 100g/Bag
- Purity
- 98%
- Supply Ability
- 300tons
- Release date
- 2021-12-20
- Product
- VITAMIN E NICOTINATE 43119-47-7
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-07-30
- Product
- VITAMIN E NICOTINATE 43119-47-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99.9%
- Supply Ability
- 200kg
- Release date
- 2020-01-12