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Calcifediol Monohydrate

Product Name
Calcifediol Monohydrate
CAS No.
63283-36-3
Chemical Name
Calcifediol Monohydrate
Synonyms
CALCIFEDIOL;25-HYDROXYVITAMIN D3;25-OH-D3;25-HYDROXYCHOLECALCIFEROL;25-OH-VD3;CALCIDIOL;25-OH-Vitamin D3;25-HYDROXYVITAMIN D3;25-HYDROXYCHOLECALCIFEROL;Calcifediol CRS;25-hydroxy VD3)
CBNumber
CB8727251
Molecular Formula
C27H46O3
Formula Weight
418.66
MOL File
63283-36-3.mol
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Calcifediol Monohydrate Property

Flash point:
14℃
storage temp. 
-20°C
solubility 
Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in fatty oils.
color 
White to Light yellow
BRN 
4270041
InChIKey
JWUBBDSIWDLEOM-LCDSLSDMSA-N
SMILES
C[C@]12CCC/C(=C\C=C3\C[C@@H](O)CCC\3=C)/[C@]1([H])CC[C@]2([H])[C@H](C)CCCC(O)(C)C.O |&1:1,10,16,20,22,r|
CAS DataBase Reference
63283-36-3(CAS DataBase Reference)
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Safety

Hazard Codes 
T+
Risk Statements 
28-48/25-26-24/25
Safety Statements 
28-36/37-45
RIDADR 
UN 2811 6.1/PG 2
WGK Germany 
3
8-10-19
HS Code 
29362900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H372Causes damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHR2359
Product name
Calcifediol
Purity
Pharmaceutical Secondary Standard; Certified Reference Material
Packaging
100MG
Price
$739
Updated
2024/03/01
Sigma-Aldrich
Product number
H-083
Product name
25-Hydroxyvitamin D3 solution
Purity
100?μg/mLinethanol,ampuleof1?mL,certifiedreferencematerial,Cerilliant?
Packaging
1mL
Price
$165
Updated
2024/03/01
Sigma-Aldrich
Product number
17938
Product name
25-Hydroxyvitamin D3 monohydrate
Purity
≥99.0% (HPLC)
Packaging
1mg
Price
$394
Updated
2024/03/01
Sigma-Aldrich
Product number
1086108
Product name
Calcifediol
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
75mg
Price
$1150
Updated
2024/03/01
TCI Chemical
Product number
C3537
Product name
Calcifediol Monohydrate
Purity
>98.0%(HPLC)
Packaging
10mg
Price
$219
Updated
2024/03/01
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Calcifediol Monohydrate Chemical Properties,Usage,Production

Chemical Properties

White or almost white crystals.

Uses

Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It is produced in the liver and is the best indicator of the body’s vitamin D stores. It is effective in the treatment of ricket

Uses

25-Hydroxyvitamin D3 may be used as a certified reference material (CRM) for the determination of the analyte in biological samples by chromatography techniques.

Definition

ChEBI: Calcifediol monohydrate is a vitamin D.

brand name

Calderol (Organon).

General Description

A Certified Spiking Solution? of 25-Hydroxyvitamin D3, a prohormone whose blood serum levels are used to determine Vitamin D nutritional status. This solution standard is suitable for critical quantitative applications in research and clinical environments including: for use in preparation of controls and calibrators for LC/UV and LC-MS/MS assays; as system tuning/suitability standards; linearity verification; internal proficiency testing; and for OEM use in preparation of reagents, development of assays and instrument IQ/OQ. The stable, quantitative solution format provides significant benefits to the user including material savings, increased efficiency of labor, and convenience of use. The shelf stable Snap-N-Spike? format allows laboratories to eliminate painstaking weighing operations and provides the ability to spike a known concentration of analyte into their matrix of choice just before use.

Biochem/physiol Actions

Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol) is a synthetic analog that is metabolized to 1,25-dihydroxycholecalciferol, the biologically active form of vitamin D3. Other analogues of cholecalciferol result from different hydroxylations. 25-dihydroxycholecalciferol is a the major circulating form of vitamin D3 and a physiological precursor of 1α,25-Dihydroxycholecalciferol. The conversion is catalyzed by 25-Hydroxyvitamin D3 1-α-hydroxylase (VD3 1A hydroxylase) also known ascytochrome p450 27B1 (CYP27B1).

target

IL Receptor

Dosage

Calcidiol monohydrate contains the monohydrate form of the major circulating metabolite of vitamin D3 in the body and is a source of 1,25-dihydroxyvitamin D, the biologically active form of vitamin D. Calciferol monohydrate (25-hydroxycholecalciferol monohydrate) is safe under recommended conditions and level of use (up to 10 μg/day) and is safe for children >11 years of age and adults, including pregnant and lactating women.

Calcifediol Monohydrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Calcifediol Monohydrate Suppliers

Zhengzhou Kangshan Biological Co., Ltd.
Tel
+86-0371-55023472 +86-13663848272
Fax
0371-55023472
Email
2584787837@qq.com
Country
China
ProdList
167
Advantage
58
Shanghai Beiwanta Biotechnology Co., Ltd.
Tel
021-67187366 19901745723
Email
info@bwtlab.com
Country
China
ProdList
9241
Advantage
58
Hubei xingongli Chemical Co., Ltd
Tel
027-59503710 15172325309
Fax
027-59503710
Email
1400858877@qq.com
Country
China
ProdList
9965
Advantage
58
HUBEI HICKS BIOCHEMICAL CO.,LTD
Tel
18696113233
Email
15927219311@163.com
Country
China
ProdList
1583
Advantage
58
Hangzhou Bingochem Co., Ltd.
Tel
0571-87632989
Email
sales@bingochem.com
Country
China
ProdList
21673
Advantage
58
Joyochem Co.,Ltd
Tel
531-82687558 13290333633
Email
sales@joyochem.com
Country
China
ProdList
19
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2923
Advantage
55
Chemvon Biotechnology Co., Ltd
Tel
021-50790412
Fax
+86-21-50790419
Email
info@chemvon.com
Country
China
ProdList
371
Advantage
57
Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057 18501085097
Fax
010-89508210
Email
sales3.gd@hwrkchemical.com
Country
China
ProdList
7583
Advantage
55
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View Lastest Price from Calcifediol Monohydrate manufacturers

airuikechemical co., ltd.
Product
calcifediol monohydrate 63283-36-3
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-10
Hebei Yanxi Chemical Co., Ltd.
Product
Calcifediol Monohydrate 63283-36-3
Price
US $10.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
30 tons
Release date
2023-09-22
Hebei Guanlang Biotechnology Co., Ltd.
Product
Calcifediol Monohydrate 63283-36-3
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2022-10-12

63283-36-3, Calcifediol MonohydrateRelated Search:


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  • APIs
  • Elisa Kit-plant ELISA Kit
  • API