Calcifediol Monohydrate
- Product Name
- Calcifediol Monohydrate
- CAS No.
- 63283-36-3
- Chemical Name
- Calcifediol Monohydrate
- Synonyms
- CALCIFEDIOL;25-HYDROXYVITAMIN D3;25-OH-D3;25-HYDROXYCHOLECALCIFEROL;25-OH-VD3;CALCIDIOL;25-OH-Vitamin D3;25-HYDROXYVITAMIN D3;25-HYDROXYCHOLECALCIFEROL;Calcifediol CRS;25-hydroxy VD3)
- CBNumber
- CB8727251
- Molecular Formula
- C27H46O3
- Formula Weight
- 418.66
- MOL File
- 63283-36-3.mol
Calcifediol Monohydrate Property
- Flash point:
- 14℃
- storage temp.
- -20°C
- solubility
- Practically insoluble in water, freely soluble in ethanol (96 per cent), soluble in fatty oils.
- color
- White to Light yellow
- BRN
- 4270041
- InChIKey
- JWUBBDSIWDLEOM-LCDSLSDMSA-N
- SMILES
- C[C@]12CCC/C(=C\C=C3\C[C@@H](O)CCC\3=C)/[C@]1([H])CC[C@]2([H])[C@H](C)CCCC(O)(C)C.O |&1:1,10,16,20,22,r|
- CAS DataBase Reference
- 63283-36-3(CAS DataBase Reference)
Safety
- Hazard Codes
- T+
- Risk Statements
- 28-48/25-26-24/25
- Safety Statements
- 28-36/37-45
- RIDADR
- UN 2811 6.1/PG 2
- WGK Germany
- 3
- F
- 8-10-19
- HS Code
- 29362900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- PHR2359
- Product name
- Calcifediol
- Purity
- Pharmaceutical Secondary Standard; Certified Reference Material
- Packaging
- 100MG
- Price
- $739
- Updated
- 2024/03/01
- Product number
- H-083
- Product name
- 25-Hydroxyvitamin D3 solution
- Purity
- 100?μg/mLinethanol,ampuleof1?mL,certifiedreferencematerial,Cerilliant?
- Packaging
- 1mL
- Price
- $165
- Updated
- 2024/03/01
- Product number
- 17938
- Product name
- 25-Hydroxyvitamin D3 monohydrate
- Purity
- ≥99.0% (HPLC)
- Packaging
- 1mg
- Price
- $394
- Updated
- 2024/03/01
- Product number
- 1086108
- Product name
- Calcifediol
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 75mg
- Price
- $1150
- Updated
- 2024/03/01
- Product number
- C3537
- Product name
- Calcifediol Monohydrate
- Purity
- >98.0%(HPLC)
- Packaging
- 10mg
- Price
- $219
- Updated
- 2024/03/01
Calcifediol Monohydrate Chemical Properties,Usage,Production
Chemical Properties
White or almost white crystals.
Uses
Calcifediol is a major circulating metabolite of vitamin D3 and acts as a competitive inhibitor with an apparent Ki of 3.9 μM. It is produced in the liver and is the best indicator of the body’s vitamin D stores. It is effective in the treatment of ricket
Uses
25-Hydroxyvitamin D3 may be used as a certified reference material (CRM) for the determination of the analyte in biological samples by chromatography techniques.
Definition
ChEBI: Calcifediol monohydrate is a vitamin D.
brand name
Calderol (Organon).
General Description
A Certified Spiking Solution? of 25-Hydroxyvitamin D3, a prohormone whose blood serum levels are used to determine Vitamin D nutritional status. This solution standard is suitable for critical quantitative applications in research and clinical environments including: for use in preparation of controls and calibrators for LC/UV and LC-MS/MS assays; as system tuning/suitability standards; linearity verification; internal proficiency testing; and for OEM use in preparation of reagents, development of assays and instrument IQ/OQ. The stable, quantitative solution format provides significant benefits to the user including material savings, increased efficiency of labor, and convenience of use. The shelf stable Snap-N-Spike? format allows laboratories to eliminate painstaking weighing operations and provides the ability to spike a known concentration of analyte into their matrix of choice just before use.
Biochem/physiol Actions
Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol) is a synthetic analog that is metabolized to 1,25-dihydroxycholecalciferol, the biologically active form of vitamin D3. Other analogues of cholecalciferol result from different hydroxylations. 25-dihydroxycholecalciferol is a the major circulating form of vitamin D3 and a physiological precursor of 1α,25-Dihydroxycholecalciferol. The conversion is catalyzed by 25-Hydroxyvitamin D3 1-α-hydroxylase (VD3 1A hydroxylase) also known ascytochrome p450 27B1 (CYP27B1).
target
IL Receptor
Dosage
Calcidiol monohydrate contains the monohydrate form of the major circulating metabolite of vitamin D3 in the body and is a source of 1,25-dihydroxyvitamin D, the biologically active form of vitamin D. Calciferol monohydrate (25-hydroxycholecalciferol monohydrate) is safe under recommended conditions and level of use (up to 10 μg/day) and is safe for children >11 years of age and adults, including pregnant and lactating women.
Calcifediol Monohydrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Calcifediol Monohydrate manufacturers
- Product
- calcifediol monohydrate 63283-36-3
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-10
- Product
- Calcifediol Monohydrate 63283-36-3
- Price
- US $10.00-1.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 30 tons
- Release date
- 2023-09-22
- Product
- Calcifediol Monohydrate 63283-36-3
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2022-10-12