2-(4-Chlorophenyl)thiazole-5-carbaldehyde

Product Name: 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
CAS No.: 721920-84-9
Chemical Name: 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
Synonyms: 2-(4-CHLOROPHENYL)THIAZOLE-5-CARBALDEHYDE;2-(4-hydroxyphenyl)thiazole-5-carbaldehyde;5-Thiazolecarboxaldehyde, 2-(4-chlorophenyl)-;2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde
CBNumber: CB8406903
Molecular Formula: C10H6ClNOS
Formula Weight: 223.68
MOL File: 721920-84-9.mol

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2-(4-Chlorophenyl)thiazole-5-carbaldehyde Property

Boiling point:: 377.6±48.0 °C(Predicted)
Density: 1.388±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
pka: 0.14±0.10(Predicted)

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Safety

Risk Statements: 43
Safety Statements: 36/37

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C995265
Product name: 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: C995265
Product name: 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
Packaging: 1g
Price: $285
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC149170
Product name: 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
Packaging: 2g
Price: $299
Updated: 2021/12/16

Matrix Scientific

Product number: 071667
Product name: 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
Purity: 95+%
Packaging: 1g
Price: $347
Updated: 2021/12/16

Ark Pharm

Product number: P000168977
Product name: 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
Purity: 95+%
Packaging: 5g
Price: $229
Updated: 2021/12/16

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2-(4-Chlorophenyl)thiazole-5-carbaldehyde Chemical Properties,Usage,Production

Synthesis

36437-19-1

2521-24-6

721920-84-9

Step 1. Synthesis of 2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde. 4-Chlorobenzamide (5 g, 29.1 mmol), magnesium bicarbonate pentahydrate (7.06 g, 14.55 mmol) and 2-chloromalonaldehyde (4.65 g, 43.65 mmol) were added to a flask and the reaction was stirred for 3 hr at 60 °C under nitrogen protection. Upon completion of the reaction, the reaction mixture was allowed to pass through a silica plug for rapid column chromatography and washed with ethyl acetate. The solvent was removed by concentration under reduced pressure to afford the target product 2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde (6 g, 92% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 10.06 (s, 1H), 8.43 (s, 1H), 7.99-7.96 (m, 2H), 7.49-7.46 (m, 2H).

References

[1] Patent: WO2004/58761, 2004, A1. Location in patent: Page 37-38
[2] Patent: WO2011/12862, 2011, A1. Location in patent: Page/Page column 102; 109

2-(4-Chlorophenyl)thiazole-5-carbaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(4-Chlorophenyl)thiazole-5-carbaldehyde Suppliers

China 32 India 2 United Kingdom 2 United States 12 Global 48

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View Lastest Price from 2-(4-Chlorophenyl)thiazole-5-carbaldehyde manufacturers

Career Henan Chemical Co

Product: 2-(4-Chlorophenyl)thiazole-5-carbaldehyde 721920-84-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95-99%
Supply Ability: 1ton
Release date: 2020-01-02

721920-84-9, 2-(4-Chlorophenyl)thiazole-5-carbaldehydeRelated Search:

Fosthiazate Chlorodimethylphenylsilane Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) Benzothiazole Triphenylmethyl Chloride ETHYL 2-(4-CHLOROPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE 1-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-5-YL]-3-(DIMETHYLAMINO)-2-PROPEN-1-ONE 2-(4-CHLOROPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLIC ACID ETHYL 2-(4-CHLOROPHENYL)-4-HYDROXY-1,3-THIAZOLE-5-CARBOXYLATE METHYL 2-(4-CHLOROPHENYL)-4-METHYL-1,3-THIAZOLE-5-CARBOXYLATE ETHYL 2-(2,4-DICHLOROPHENYL)-4-HYDROXYTHIAZOLE-5-CARBOXYLATE 2-(4-Chlorophenyl)thiazole-5-carbaldehyde [2-(4-CHLOROPHENYL)-1,3-THIAZOL-5-YL](PHENYL)METHANONE [1,1'-BIPHENYL]-4-YL[2-(4-CHLOROPHENYL)-1,3-THIAZOL-5-YL]METHANONE 3-[2-(4-CHLOROPHENYL)-1,3-THIAZOL-5-YL]-3-OXOPROPANAL O-(2-[3-(TRIFLUOROMETHYL)PHENOXY]ETHYL)OXIME (4-BROMOPHENYL)[2-(4-CHLOROPHENYL)-1,3-THIAZOL-5-YL]METHANONE [2-(4-CHLOROPHENYL)-1,3-THIAZOL-5-YL](3,4-DICHLOROPHENYL)METHANONE 2-(4-CHLOROPHENYL)-4-METHYL-N-[3-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOLE-5-CARBOXAMIDE

2-(4-CHLOROPHENYL)THIAZOLE-5-CARBALDEHYDE

2-(4-hydroxyphenyl)thiazole-5-carbaldehyde

2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde

5-Thiazolecarboxaldehyde, 2-(4-chlorophenyl)-

721920-84-9

C10H6ClNOS

API intermediates