2-(4-Chlorophenyl)thiazole-5-carbaldehyde
- Product Name
- 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
- CAS No.
- 721920-84-9
- Chemical Name
- 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
- Synonyms
- 2-(4-CHLOROPHENYL)THIAZOLE-5-CARBALDEHYDE;2-(4-hydroxyphenyl)thiazole-5-carbaldehyde;5-Thiazolecarboxaldehyde, 2-(4-chlorophenyl)-;2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde
- CBNumber
- CB8406903
- Molecular Formula
- C10H6ClNOS
- Formula Weight
- 223.68
- MOL File
- 721920-84-9.mol
2-(4-Chlorophenyl)thiazole-5-carbaldehyde Property
- Boiling point:
- 377.6±48.0 °C(Predicted)
- Density
- 1.388±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- pka
- 0.14±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C995265
- Product name
- 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- C995265
- Product name
- 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
- Packaging
- 1g
- Price
- $285
- Updated
- 2021/12/16
- Product number
- FC149170
- Product name
- 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
- Packaging
- 250mg
- Price
- $57.5
- Updated
- 2021/12/16
- Product number
- P000168977
- Product name
- 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
- Purity
- 95+%
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FC149170
- Product name
- 2-(4-Chlorophenyl)thiazole-5-carbaldehyde
- Packaging
- 500mg
- Price
- $100
- Updated
- 2021/12/16
2-(4-Chlorophenyl)thiazole-5-carbaldehyde Chemical Properties,Usage,Production
Synthesis
36437-19-1
2521-24-6
721920-84-9
Step 1. Synthesis of 2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde. 4-Chlorobenzamide (5 g, 29.1 mmol), magnesium bicarbonate pentahydrate (7.06 g, 14.55 mmol) and 2-chloromalonaldehyde (4.65 g, 43.65 mmol) were added to a flask and the reaction was stirred for 3 hr at 60 °C under nitrogen protection. Upon completion of the reaction, the reaction mixture was allowed to pass through a silica plug for rapid column chromatography and washed with ethyl acetate. The solvent was removed by concentration under reduced pressure to afford the target product 2-(4-chlorophenyl)-1,3-thiazole-5-carbaldehyde (6 g, 92% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 10.06 (s, 1H), 8.43 (s, 1H), 7.99-7.96 (m, 2H), 7.49-7.46 (m, 2H).
References
[1] Patent: WO2004/58761, 2004, A1. Location in patent: Page 37-38
[2] Patent: WO2011/12862, 2011, A1. Location in patent: Page/Page column 102; 109
2-(4-Chlorophenyl)thiazole-5-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(4-Chlorophenyl)thiazole-5-carbaldehyde manufacturers
- Product
- 2-(4-Chlorophenyl)thiazole-5-carbaldehyde 721920-84-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95-99%
- Supply Ability
- 1ton
- Release date
- 2020-01-02