ChemicalBook > CAS DataBase List > PYRROLIDIN-1-YL-ACETIC ACID

PYRROLIDIN-1-YL-ACETIC ACID

Product Name
PYRROLIDIN-1-YL-ACETIC ACID
CAS No.
37386-15-5
Chemical Name
PYRROLIDIN-1-YL-ACETIC ACID
Synonyms
AKOS BC-0363;AKOS BBS-00000323;RARECHEM AL BO 0350;SALOR-INT L481092-1EA;1-PYRROLIDINEACETIC ACID;N-PYRROLIDINOACETIC ACID;1-PYRROLIDINYLACETIC ACID;1-Pyrroltdinylacetic acid;Pyrroldin-1-yl-acetic acid;PYRROLIDIN-1-YL-ACETIC ACID
CBNumber
CB8412478
Molecular Formula
C6H11NO2
Formula Weight
129.16
MOL File
37386-15-5.mol
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PYRROLIDIN-1-YL-ACETIC ACID Property

Melting point:
184-185 °C
Boiling point:
233.8±23.0 °C(Predicted)
Density 
1.153±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
DMSO (Slightly, Sonicated, Heated), Methanol (Slightly)
form 
Solid
pka
2.47±0.10(Predicted)
color 
Pale Yellow
InChI
InChI=1S/C6H11NO2/c8-6(9)5-7-3-1-2-4-7/h1-5H2,(H,8,9)
InChIKey
IPXNXMNCBXHYLQ-UHFFFAOYSA-N
SMILES
N1(CC(O)=O)CCCC1
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Safety

Hazard Codes 
Xi
HazardClass 
IRRITANT
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
L481092
Product name
1-PYRROLIDINYLACETIC ACID
Purity
Aldrich<sup>CPR</sup>
Packaging
1 unit
Price
$185
Updated
2025/07/31
Sigma-Aldrich
Product number
L481092
Product name
1-PYRROLIDINYLACETIC ACID
Purity
Aldrich
Packaging
250mg
Price
$179
Updated
2024/03/01
TRC
Product number
P998495
Product name
1-​PyrrolidineaceticAcid
Packaging
2.5g
Price
$275
Updated
2021/12/16
AK Scientific
Product number
Y8903
Product name
Pyrrolidin-1-ylaceticacid
Packaging
1g
Price
$111
Updated
2021/12/16
Matrix Scientific
Product number
027154
Product name
Pyrrolidin-1-ylacetic acid
Packaging
500mg
Price
$153
Updated
2021/12/16
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PYRROLIDIN-1-YL-ACETIC ACID Chemical Properties,Usage,Production

Uses

1-?Pyrrolidineacetic Acid is a useful reactant and reagent in organic reactions. It can be found used in cosmetic products such as wrinkle-?preventive?/ameliorating products.

Synthesis

22041-19-6

37386-15-5

b) Synthesis of 2-(pyrrolidin-1-yl)acetic acid: ethyl 2-(pyrrolidin-1-yl)acetate (2 g, 12.7 mmol, 1.0 eq.) was dissolved in 8N HCl and the reaction was stirred for 16 hrs. at 95°C. Upon completion of the reaction, the mixture was concentrated, the reaction was quenched and extracted as in Intermediate Example 15(b). Subsequently, the solvent was removed by distillation to afford the target product 2-(pyrrolidin-1-yl)acetic acid in 91% (1.5 g) yield. The product was analyzed by LC-MS (ESI): calculated mass 129.1; measured mass 130.1 [M + H]+ (retention time: 0.26 min).

References

[1] Patent: WO2013/53983, 2013, A1. Location in patent: Page/Page column 40
[2] Patent: US2015/11548, 2015, A1. Location in patent: Paragraph 0161
[3] Liebigs Annalen der Chemie, 1983, # 6, p. 950 - 961

PYRROLIDIN-1-YL-ACETIC ACID Preparation Products And Raw materials

Raw materials

Ethanol Bromoacetic acid Sodium hydroxide Pyrrolidine

Preparation Products

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PYRROLIDIN-1-YL-ACETIC ACID Suppliers

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View Lastest Price from PYRROLIDIN-1-YL-ACETIC ACID manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
PYRROLIDIN-1-YL-ACETIC ACID 37386-15-5
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-20
Shaanxi Dideu New Materials Co. Ltd
Product
PYRROLIDIN-1-YL-ACETIC ACID 37386-15-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10000KGS
Release date
2025-03-18

37386-15-5, PYRROLIDIN-1-YL-ACETIC ACIDRelated Search:

ETHYL PYRROLIDINOACETATE PHENYL-PYRROLIDIN-1-YL-ACETIC ACID METHYL1-PYRROLIDINEACETATE (R)-METHYL 2-(PYRROLIDIN-2-YL)ACETATE METHYL (2S)-PYRROLIDIN-2-YLACETATE 2-(pyrrolidin-3-yl)acetic acid (R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID N-beta-(t-Butyloxycarbonyl)-L-homoproline, (S)-N-t-Butyloxycarbonyl-2-(pyrrolidin-2-yl)acetic acid 2-(1-(TERT-BUTOXYCARBONYL)PYRROLIDIN-3-YL)ACETIC ACID L-beta-Homoproline, (S)-2-(Pyrrolidin-2-yl)acetic acid hydrochloride (S)-(1-Boc-pyrrolidin-3-yl)acetic acid 2-pyrrolidin-1-ylacetic acid N-beta-(9-Fluorenylmethyloxycarbonyl)-L-homoproline, (S)-N-(9-Fluorenylmethyloxycarbonyl)-2-(pyrrolidin-2-yl)acetic acid (2,5-DIOXO-PYRROLIDIN-1-YL)-ACETIC ACID CARBOMETHOXYCARBONYL-D-PRO-D-PHE BENZYL ESTER CARBOMETHOXYCARBONYL-PRO-PHE-OBZL 2-(3,5-DIOXO-4-AZATRICYCLO[5.2.1.0(2,6)]DEC-8-EN-4-YL)-4-METHYLPENTANOIC ACID 4-(4-METHYLPHENYL)-4-OXO-2-(1-PYRROLIDINYL)BUTANOIC ACID

  • AKOS BBS-00000323
  • AKOS BC-0363
  • 1-PYRROLIDINEACETIC ACID
  • 1-PYRROLIDINYLACETIC ACID
  • N-PYRROLIDINOACETIC ACID
  • SALOR-INT L481092-1EA
  • PYRROLIDIN-1-YL-ACETIC ACID
  • RARECHEM AL BO 0350
  • Pyrroldin-1-yl-acetic acid
  • 1-Pyrrolidinylacetic acid N-Pyrrolidinoacetic acid
  • pyrrolidin-1-ylacetic acid(SALTDATA: FREE)
  • 1-Pyrroltdinylacetic acid
  • 2-(1-Pyrrolidyl)acetic Acid
  • Eravacycline intermediate F
  • 37386-15-5