(R)-N-Boc-3-pyrrolidineacetic acid
Uses- Product Name
- (R)-N-Boc-3-pyrrolidineacetic acid
- CAS No.
- 204688-60-8
- Chemical Name
- (R)-N-Boc-3-pyrrolidineacetic acid
- Synonyms
- (R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid;(R)-N-Boc-3-pyrrolidineacetic;N-BOC-(R)-pyrrolidin-3-acetic acid;(R)-1-Boc-3-pyrrolidineacetic acid;(R)-N-BOC-3-PYRROLIDINEACETIC ACID;(R)-N-BOC-PYRROLIDINE-3-ACETIC ACID;(3R)-1-Boc-3-pyrrolidineacetic acid;(R)-1-N-Boc-3-pyrrolidineacetic acid;(R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID;(R)-2-(1-Boc-3-pyrrolidinyl)acetic Acid
- CBNumber
- CB6409081
- Molecular Formula
- C11H19NO4
- Formula Weight
- 229.27
- MOL File
- 204688-60-8.mol
(R)-N-Boc-3-pyrrolidineacetic acid Property
- Boiling point:
- 357.4±15.0 °C(Predicted)
- Density
- 1.151±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 4.65±0.10(Predicted)
- InChI
- InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-5-4-8(7-12)6-9(13)14/h8H,4-7H2,1-3H3,(H,13,14)/t8-/m1/s1
- InChIKey
- SKEXQIJIXQSFRX-MRVPVSSYSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CC[C@H](CC(O)=O)C1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B662065
- Product name
- (R)-(1-BOC-Pyrrolidin-3-yl)aceticAcid
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- V0497
- Product name
- (R)-(1-Boc-Pyrrolidin-3-yl)-aceticacid
- Packaging
- 250mg
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FB41693
- Product name
- (R)-(1-Boc-pyrrolidin-3-yl)-acetic acid
- Packaging
- 250mg
- Price
- $85
- Updated
- 2021/12/16
- Product number
- P12300
- Product name
- (R)-1-Boc-3-pyrrolidineaceticacid
- Purity
- 95+%
- Packaging
- 1g
- Price
- $30
- Updated
- 2021/12/16
- Product number
- P12300
- Product name
- (R)-1-Boc-3-pyrrolidineaceticacid
- Purity
- 95+%
- Packaging
- 5g
- Price
- $100
- Updated
- 2021/12/16
(R)-N-Boc-3-pyrrolidineacetic acid Chemical Properties,Usage,Production
Uses
(R)-N-Boc-3-tetrahydropyrrolic acid is an important pharmaceutical synthesis intermediate widely used in organic synthesis. It can act as an introducing agent for amine protecting groups, protecting the amine groups from side reactions during synthesis.
Synthesis
(R)-N-Boc-3-pyrrolidineacetic acid is synthesised using Di-tert-butyl dicarbonate as raw material by chemical reaction. The specific synthesis steps are as follows:
A solution of 4.95 g of the preceding step product in 50 ml of dichloromethane and 25 ml of trifluoroacetic acid is stirred at room temperature for 3 h. and concentrated. The residue is dissolved in 40 ml of dioxan and 40 ml of 1N NaOH, treated at room temperature with 4.3 g of di-tert-butyl dicarbonate in 40 ml of dioxan and stirred for 1.5 h. The reaction mixture is diluted with ether, the organic phase is washed with 1N NaOH and the aqueous phase is acidified with 3N HCl. Extraction of the aqueous phase with ether, washing, drying and concentration of the ether phase gives 0.72 g of tert-butyl(R)-3-carboxymethyl-pyrrolidine-1-carboxylate.
(R)-N-Boc-3-pyrrolidineacetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from (R)-N-Boc-3-pyrrolidineacetic acid manufacturers
- Product
- (R)-N-Boc-3-pyrrolidineacetic acid 204688-60-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- Customized
- Release date
- 2019-12-17