ChemicalBook > CAS DataBase List > (R)-N-Boc-3-pyrrolidineacetic acid

(R)-N-Boc-3-pyrrolidineacetic acid

Uses

Product Name: (R)-N-Boc-3-pyrrolidineacetic acid
CAS No.: 204688-60-8
Chemical Name: (R)-N-Boc-3-pyrrolidineacetic acid
Synonyms: (R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid;(R)-N-Boc-3-pyrrolidineacetic;N-BOC-(R)-pyrrolidin-3-acetic acid;(R)-1-Boc-3-pyrrolidineacetic acid;(R)-N-BOC-3-PYRROLIDINEACETIC ACID;(R)-N-BOC-PYRROLIDINE-3-ACETIC ACID;(3R)-1-Boc-3-pyrrolidineacetic acid;(R)-1-N-Boc-3-pyrrolidineacetic acid;(R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID;(R)-2-(1-Boc-3-pyrrolidinyl)acetic Acid
CBNumber: CB6409081
Molecular Formula: C11H19NO4
Formula Weight: 229.27
MOL File: 204688-60-8.mol

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(R)-N-Boc-3-pyrrolidineacetic acid Property

Boiling point:: 357.4±15.0 °C(Predicted)
Density: 1.151±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.65±0.10(Predicted)
InChI: InChI=1S/C11H19NO4/c1-11(2,3)16-10(15)12-5-4-8(7-12)6-9(13)14/h8H,4-7H2,1-3H3,(H,13,14)/t8-/m1/s1
InChIKey: SKEXQIJIXQSFRX-MRVPVSSYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CC[C@H](CC(O)=O)C1

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Safety

Hazard Codes: T,N
Risk Statements: 25-50
Safety Statements: 45-61
RIDADR: UN2811
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: B662065
Product name: (R)-(1-BOC-Pyrrolidin-3-yl)aceticAcid
Packaging: 100mg
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: V0497
Product name: (R)-(1-Boc-Pyrrolidin-3-yl)-aceticacid
Packaging: 250mg
Price: $80
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB41693
Product name: (R)-(1-Boc-pyrrolidin-3-yl)-acetic acid
Packaging: 250mg
Price: $85
Updated: 2021/12/16

Synthonix

Product number: P12300
Product name: (R)-1-Boc-3-pyrrolidineaceticacid
Purity: 95+%
Packaging: 1g
Price: $30
Updated: 2021/12/16

Synthonix

Product number: P12300
Product name: (R)-1-Boc-3-pyrrolidineaceticacid
Purity: 95+%
Packaging: 5g
Price: $100
Updated: 2021/12/16

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(R)-N-Boc-3-pyrrolidineacetic acid Chemical Properties,Usage,Production

Uses

(R)-N-Boc-3-tetrahydropyrrolic acid is an important pharmaceutical synthesis intermediate widely used in organic synthesis. It can act as an introducing agent for amine protecting groups, protecting the amine groups from side reactions during synthesis.

Synthesis

(R)-N-Boc-3-pyrrolidineacetic acid is synthesised using Di-tert-butyl dicarbonate as raw material by chemical reaction. The specific synthesis steps are as follows:
A solution of 4.95 g of the preceding step product in 50 ml of dichloromethane and 25 ml of trifluoroacetic acid is stirred at room temperature for 3 h. and concentrated. The residue is dissolved in 40 ml of dioxan and 40 ml of 1N NaOH, treated at room temperature with 4.3 g of di-tert-butyl dicarbonate in 40 ml of dioxan and stirred for 1.5 h. The reaction mixture is diluted with ether, the organic phase is washed with 1N NaOH and the aqueous phase is acidified with 3N HCl. Extraction of the aqueous phase with ether, washing, drying and concentration of the ether phase gives 0.72 g of tert-butyl(R)-3-carboxymethyl-pyrrolidine-1-carboxylate.

(R)-N-Boc-3-pyrrolidineacetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from (R)-N-Boc-3-pyrrolidineacetic acid manufacturers

Career Henan Chemical Co

Product: (R)-N-Boc-3-pyrrolidineacetic acid 204688-60-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Customized
Release date: 2019-12-17

204688-60-8, (R)-N-Boc-3-pyrrolidineacetic acidRelated Search:

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(R)-1-Boc-3-pyrrolidineacetic acid

(R)-N-Boc-3-(R)-(1-Boc-Pyrrolidin-3-yl)-aceticacid

(R)-2-(1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)acetic acid

2-[(3R)-1-[(tert-butoxy)carbonyl]pyrrolidin-3-yl]acetic acid

(R)-3-CARBOXYMETHYL-PYRROLIDINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER

(R)-(1-BOC-PYRROLIDIN-3-YL)-ACETIC ACID

(R)-N-BOC-PYRROLIDINE-3-ACETIC ACID

(R)-N-BOC-3-PYRROLIDINEACETIC ACID

(R)-1-N-Boc-3-pyrrolidineacetic acid

N-BOC-(R)-pyrrolidin-3-acetic acid

2-[(3S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]acetic acid

(R)-2-(1-Boc-3-pyrrolidinyl)acetic Acid

(3R)-1-Boc-3-pyrrolidineacetic acid

3-Pyrrolidineacetic acid, 1-[(1,1-dimethylethoxy)carbonyl]-, (3R)-

(R)-1-tert-Butoxycarbonylpyrrolidine-3-acetic acid

2-[(3R)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-3-yl]acetic acid

(R)-3-carboxymethyl-pyrrolidin-1-carboxylic acid tert-butyl ester

(R)-(1-Boc-Pyrrolidin-3-yl)-acetic acid, CAS 204688-60-8

(R)-1-Boc-3-pyrrolidine acetic acid - [P12300]

(R)-N-Boc-3-pyrrolidineacetic

204688-60-8

pharmacetical