CHARTREUSIN Property

Melting point:

185℃

alpha 

D25 +132.5° (c = 0.2 in pyridine); D25 -33° (c = 0.3 in glacial acetic acid)

Boiling point:

592.39°C (rough estimate)

Density 

1.3027 (rough estimate)

refractive index 

1.6130 (estimate)

storage temp. 

2-8°C

solubility 

Chloroform (Slightly, Heated), Methanol (Slightly), Pyridine (Slightly)

form 

Yellow solid.

pka

6?+-.0.20(Predicted)

color 

Light Yellow to Yellow

Water Solubility 

15mg/L(25 ºC)

Stability:

Hygroscopic

Safety

Hazard Codes 

Xn

Risk Statements 

40

Safety Statements 

22-36/37/39-45

HS Code 

29419000

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P281Use personal protective equipment as required.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

CHARTREUSIN Chemical Properties,Usage,Production

Uses

Chartreusin is an antiproliferative agent that inhibits topoisomerase II.

Uses

Chartreusin is an antitumour antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II.

Uses

Chartreusin is an antitumor antibiotic that binds to GC-rich tracts in DNA, with a clear preference for B-DNA over Z-DNA. It inhibits RNA synthesis and causes single-strand scission of DNA via the formation of free radicals. Chartreusin is also a potent inhibitor of topoisomerase II.

Definition

ChEBI: Chartreusin is a glycoside and a benzochromenone.