BENZYL GLYCOLATE
- Product Name
- BENZYL GLYCOLATE
- CAS No.
- 30379-58-9
- Chemical Name
- BENZYL GLYCOLATE
- Synonyms
- Benzyl 2-hydroxyacetate;BENZYL GLYCOLATE;Benzyl glycolate 97%;Phenylmethyl glycolate;Ethanol,6-(propylamino)-;BENZYL 2-HYDROXYACETATE 98%;Phenylmethyl 2-hydroxyacetate;Acetic acid, hydroxy-, phenylMethyl ester;Acetic acid, 2-hydroxy-, phenylmethyl ester
- CBNumber
- CB8437646
- Molecular Formula
- C9H10O3
- Formula Weight
- 166.17
- MOL File
- 30379-58-9.mol
BENZYL GLYCOLATE Property
- Boiling point:
- 136 °C/14 mmHg (lit.)
- Density
- 1.171 g/mL at 25 °C (lit.)
- refractive index
- n20/D 1.527(lit.)
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly), Methanol (Slightly)
- form
- Oil
- pka
- 12.96±0.10(Predicted)
- color
- Colourless
- InChI
- InChI=1S/C9H10O3/c10-6-9(11)12-7-8-4-2-1-3-5-8/h1-5,10H,6-7H2
- InChIKey
- VPYJBEIOKFRWQZ-UHFFFAOYSA-N
- SMILES
- C(OCC1=CC=CC=C1)(=O)CO
Safety
- WGK Germany
- 3
- HS Code
- 2918199890
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 410926
- Product name
- Benzyl glycolate
- Purity
- 97%
- Packaging
- 5ml
- Price
- $90.06
- Updated
- 2025/07/31
- Product number
- 410926
- Product name
- Benzyl glycolate
- Purity
- 97%
- Packaging
- 25ml
- Price
- $332.5
- Updated
- 2025/07/31
- Product number
- P2927
- Product name
- Benzyl Glycolate
- Purity
- min. 98.0 %
- Packaging
- 5G
- Price
- $53
- Updated
- 2025/07/31
- Product number
- P2927
- Product name
- Benzyl Glycolate
- Purity
- min. 98.0 %
- Packaging
- 25G
- Price
- $161
- Updated
- 2025/07/31
- Product number
- B277050
- Product name
- Benzyl glycolate
- Packaging
- 25g
- Price
- $220
- Updated
- 2021/12/16
BENZYL GLYCOLATE Chemical Properties,Usage,Production
Uses
Benzyl Glycolate was utilized as a potential moiety for the preparation of phosphonate dipeptides as potential inhibitors of VanX.
Uses
Benzyl glycolate may be used for the synthesis of the methyl [2-(2′-benzyloxy-2′-oxoethyl)-5-acetamido-4,7,8,9- tetra-O-acetyl-3,5-dideoxy-α- and -β-D-glycero-D-galacto-2-nonulopyranosid]onate. It may be used for the preparation of monosaccharide building blocks. It may also be used for the synthesis of the following new polymeric phosphazenes having pendent esters of glycolic or lactic acid as side units:
- poly[bis(ethyl glycolato)phosphazene]
- poly[bis(ethyl lactato)phosphazene]
- poly[bis(benzyl glycolato)phosphazene]
- poly[bis(benzyl lactato)phosphazene]
General Description
Benzyl glycolate is a benzyl ester of glycolic acid.
Synthesis
79-14-1
100-39-0
30379-58-9
The general procedure for the synthesis of phenylmethyl ethanoate from ethanoic acid and benzyl bromide was as follows: first, a suspension formed by 2-hydroxyacetic acid (70% aqueous solution, 889 mg, 12.0 mmol) and Cs2CO3 (1955 mg, 6.00 mmol) in a solvent mixture of methanol (22 mL) and water (4 mL) was stirred for 30 min at room temperature. Subsequently, the solvent was removed and the residue was dissolved in DMF (18 mL) pre-cooled to 0 °C. After 10 min, benzyl bromide (2155 mg, 12.6 mmol) was added and the reaction mixture was continued to be stirred for 24 h at room temperature. Upon completion of the reaction, the reaction was quenched with brine (20 mL) and the organic layer was extracted with ethyl acetate (3 x 25 mL). The extract was washed sequentially with water (25 mL) and brine (20 mL), dried over MgSO4 and concentrated in vacuum to afford 1877 mg (97% yield) of benzyl 2-hydroxyacetate as a colorless liquid.HPLC analysis showed a retention time of 2.68 min (70%).
References
[1] Bioorganic and Medicinal Chemistry, 2011, vol. 19, # 16, p. 4903 - 4909
[2] Journal of Organic Chemistry, 2000, vol. 65, # 22, p. 7667 - 7675
[3] Patent: US2016/340365, 2016, A1. Location in patent: Paragraph 0126; 0127
[4] Patent: US2016/297784, 2016, A1. Location in patent: Paragraph 0150; 0151
[5] Journal of the American Chemical Society, 2010, vol. 132, # 31, p. 10920 - 10934
BENZYL GLYCOLATE Preparation Products And Raw materials
Raw materials
Preparation Products
BENZYL GLYCOLATE Suppliers
- Tel
- +1-2266000236
- sales@rdscientific.com
- Country
- Canada
- ProdList
- 1920
- Advantage
- 58
- Tel
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- Fax
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- info@trc-canada.com
- Country
- Canada
- ProdList
- 6038
- Advantage
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View Lastest Price from BENZYL GLYCOLATE manufacturers
- Product
- BENZYL GLYCOLATE 30379-58-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-07-25
- Product
- benzyl 2-hydroxyacetate 30379-58-9
- Price
- US $990.00/Kg
- Min. Order
- 1Kg
- Purity
- 98
- Supply Ability
- 500 Kg
- Release date
- 2024-07-11
- Product
- BENZYL GLYCOLATE 30379-58-9
- Price
- US $8.80/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 100kg
- Release date
- 2019-07-04