5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE

Uses

Product Name: 5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE
CAS No.: 405224-24-0
Chemical Name: 5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE
Synonyms: 3-Amino-5-bromo-1H-pyrazo...;5-Bromo-1H-pyrazole[3,4-b]pyridin-3-amine;5-bromo-2H-pyrazolo[3,4-b]pyridin-3-amine;5-Bromo-1H-pyrazolo[3,4-b]pyridin-4-amine;5-Bromo-1H-pyrazolo[3,4-b]pyridin-ylamine;5-bromo-1H-pyrazolo[3,4-b]pyridine-3-amine;1H-Pyrazolo[3,4-b]pyridin-3-aMine,5-broMo-;3-Amino-5-bromo-1H-pyrazolo[3,4-B]pyridine;5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE;5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine
CBNumber: CB8438153
Molecular Formula: C6H5BrN4
Formula Weight: 213.03
MOL File: 405224-24-0.mol

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5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE Property

Boiling point:: 429.1±40.0 °C(Predicted)
Density: 1.994
storage temp.: 2-8°C(protect from light)
form: solid
pka: 9.55±0.40(Predicted)
Appearance: Light yellow to yellow Solid
InChI: InChI=1S/C6H5BrN4/c7-3-1-4-5(8)10-11-6(4)9-2-3/h1-2H,(H3,8,9,10,11)
InChIKey: SSNUTEUZXZIYTB-UHFFFAOYSA-N
SMILES: C12NN=C(N)C1=CC(Br)=CN=2

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BLN00005
Product name: 5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine
Purity: Aldrich
Packaging: 1g
Price: $475
Updated: 2025/07/31

Biosynth Carbosynth

Product number: FB52071
Product name: 5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-ylamine
Packaging: 2g
Price: $513.2
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H30-9-V2
Product name: 3-Amino-5-bromo-1H-pyrazolo[3,4-b]pyridine
Packaging: 5G
Price: $288
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB52071
Product name: 5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-ylamine
Packaging: 1g
Price: $320.8
Updated: 2021/12/16

ChemScene

Product number: CS-W022298
Product name: 5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine
Packaging: 10g
Price: $400
Updated: 2021/12/16

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5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE Chemical Properties,Usage,Production

Uses

3-Amino-5-bromo-1H-pyrazolo[3,4-B]pyridine is an organic intermediate.

Synthesis

405224-23-9

405224-24-0

General procedure for the synthesis of 3-amino-5-bromo-1H-pyrazolo[3,4-b]pyridine from 5-bromo-2-chloronicotinonitrile: Compound 3 (5-bromo-2-chloronicotinonitrile, 307 mg, 1.4 mmol) was dissolved in ethanol (10 mL) in a microwave reactor tube, followed by the addition of 5 equiv. of hydrazine hydrate (NH2NH2-H2O) to the solution. The reaction mixture was placed in a microwave reactor and radiated at 170 °C for 10 min. Upon completion of the reaction, the solvent was removed by rotary evaporator to afford the target product 3-amino-5-bromo-1H-pyrazolo[3,4-b]pyridine (4) in quantitative yield.

References

[1] Patent: WO2007/59219, 2007, A1. Location in patent: Page/Page column 54-55
[2] Patent: WO2016/26549, 2016, A1. Location in patent: Page/Page column 43
[3] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 20, p. 5578 - 5585
[4] Bioorganic and Medicinal Chemistry Letters, 2003, vol. 13, # 9, p. 1577 - 1580
[5] Patent: WO2013/42035, 2013, A1. Location in patent: Page/Page column 17

5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE Suppliers

China 112 Germany 1 India 1 United Kingdom 2 United States 11 Global 127

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View Lastest Price from 5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE manufacturers

Career Henan Chemical Co

Product: 5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE 405224-24-0
Price: US $5.00/KG
Min. Order: 1KG
Purity: 95%-98%
Supply Ability: 100kg
Release date: 2019-09-03

405224-24-0, 5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINERelated Search:

3-Aminopyrazine-2-carboxylic acid 3-Nitro-1H-pyrazole Homopiperazine 1H-PYRAZOLO[3,4-B]PYRIDINE 5-BROMO-4,6-DIMETHYL-1H-PYRAZOLO[3,4-B]PYRIDIN-3-AMINE 5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE 5-BROMO-1H-PYRAZO[3,4-B]PYRIDINE

5-BROMO-1H-PYRAZOLO[3,4-B]PYRIDIN-3-YLAMINE

3-Amino-5-bromo-1H-pyrazolo[3,4-B]pyridine

3-Amino-5-bromo-1H-pyrazo...

5-Bromo-1H-pyrazolo[3,4-b]pyridin-3-amine, 3-Amino-7-aza-5-bromo-1H-indazole

1H-Pyrazolo[3,4-b]pyridin-3-aMine,5-broMo-

5-Bromo-1H-pyrazole[3,4-b]pyridin-3-amine

5-bromo-1H-pyrazolo[3,4-b]pyridine-3-amine

5-Bromo-1H-pyrazolo[3,4-b]pyridin-ylamine

5-Bromo-1H-pyrazolo[3,4-b]pyridin-4-amine

5-bromo-2H-pyrazolo[3,4-b]pyridin-3-amine

5-Bromo-1<i>H</i>-pyrazolo[3,4-b]pyridin-3-amine

405224-24-0