Ganciclovir sodium
- Product Name
- Ganciclovir sodium
- CAS No.
- 107910-75-8
- Chemical Name
- Ganciclovir sodium
- Synonyms
- Unii-02L083W284;Rs 21592 sodium;GANCICLOVIR SODIUM;Sodium Ganciclovir;Cytovene IV sodium;Gancyclovir sodium;Ganciclovir Impurity 7;Ganciclovir Sodium Salt;Ganciclovir sodium, >=98%;Ganciclovir monosodium salt
- CBNumber
- CB8443489
- Molecular Formula
- C9H14N5NaO4
- Formula Weight
- 279.23
- MOL File
- 107910-75-8.mol
Ganciclovir sodium Property
- storage temp.
- Store at 4°C, protect from light
- solubility
- DMSO: 5 mg/mL (17.91 mM)
- form
- Solid
- color
- White to off-white
- Water Solubility
- Water: 50 mg/mL (179.06 mM)
- InChI
- InChI=1S/C9H13N5O4.Na.H/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16;;/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17);;
- InChIKey
- HKZYYRUGZQKKFS-UHFFFAOYSA-N
- SMILES
- C(N1C=NC2C(NC(N)=NC1=2)=O)OC(CO)CO.[NaH]
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
H351Suspected of causing cancer
H361Suspected of damaging fertility or the unborn child
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- G235050
- Product name
- GanciclovirSodiumSalt
- Packaging
- 10mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 451075
- Product name
- Ganciclovir Sodium Salt
- Packaging
- 25mg
- Price
- $489
- Updated
- 2021/12/16
- Product number
- J52395
- Product name
- Ganciclovirsodium
- Packaging
- 500mg
- Price
- $595
- Updated
- 2021/12/16
- Product number
- API0024397
- Product name
- GANCICLOVIR SODIUM
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $962.92
- Updated
- 2021/12/16
- Product number
- CS-0013616
- Product name
- Ganciclovirsodium
- Purity
- 99.85%
- Packaging
- 100mg
- Price
- $66
- Updated
- 2021/12/16
Ganciclovir sodium Chemical Properties,Usage,Production
Uses
Ganciclovir Sodium Salt is an inhibitor of the Herpesvirus family. It can be used in analytical study of establishment of a Raman database for non-invasive and rapid screening of liquid injectables.
brand name
Cytovene (Roche).
in vivo
Ganciclovir (BW 759) (50 mg/kg; i.p.; twice a day for five injections) significantly decreases white blood cells, red blood cells and platelets in newborn mice, and can diffuse into the brain and the perilymphatic space of the inner ear[3].
Ganciclovir (1-80 mg/kg; i.h.; daily for 5 days) delays murine cytomegalovirus (MCMV)-induced wasting syndrome and mortality[6].
| Animal Model: | Non-inbred Oncins France 1 (OF1) mice and albino rats non-immunized for MCMV[3] |
| Dosage: | 50 mg/kg |
| Administration: | Intraperitoneal injection, twice a day for five injections (mice) or 3 days (adult rats) (Pharmacokinetic Study) |
| Result: | In adult rats, the intracochlear diffusion of Ganciclovir was shown to achieve the same concentration as in blood. In gestating mice, transplacental diffusion was observed, with a fetal-to-maternal blood ratio of 0.5. In newborn mice, the plasma concentration profile of Ganciclovir showed a peak at 2 h followed by a gradual decrease. In adult mice, the concentration peaked at 1 h, but became undetectable by 2 h after injection. Significantly decreased white blood cells, red blood cells and platelets in newborn mice. |
| Animal Model: | Female SCID mice inoculated with MCMV[6] |
| Dosage: | 0, 1, 10, 80 and 160 mg/kg |
| Administration: | Subcutaneous injection, once daily for 5 days |
| Result: | Dose dependently delayed the wasting syndrome and mortality in a dose range up to 80 mg/kg per day, whereas a dose of 160 mg/kg per day induced reversible side-effects. |
IC 50
CMV; HSV-1; HSV-2; FHV-1: 5.2 μM (IC50)
Ganciclovir sodium Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ganciclovir sodium manufacturers
- Product
- Ganciclovir sodium 107910-75-8
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-09-29
- Product
- Ganciclovir sodium 107910-75-8
- Price
- US $2.00-5.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-13
- Product
- Ganciclovir sodium 107910-75-8
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kg
- Release date
- 2021-11-16