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Valganciclovir

Product Name
Valganciclovir
CAS No.
175865-60-8
Chemical Name
Valganciclovir
Synonyms
Valgancyclovir;Valganciclov;valganciclovir;Valganciclovir-d8;Valganciclovir-d8 (Mixture of Diastereomers);Valganciclovir & Valganciclovir Hydrochloride;Valganciclovir-d5 HCl (Mixture of diastetroMers);L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester;(2S)-2-((2-AMino-6-oxo-1H-purin-9(6H)-yl)Methoxy)-3-hydroxypropyl 2-aMino-3-Methylbutanoate;2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester
CBNumber
CB0855239
Molecular Formula
C14H22N6O5
Formula Weight
354.36
MOL File
175865-60-8.mol
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Valganciclovir Property

Density 
1.59±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
pka
9.32±0.20(Predicted)
BCS Class
3
CAS DataBase Reference
175865-60-8(CAS DataBase Reference)
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Safety

Hazardous Substances Data
175865-60-8(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Medical Isotopes, Inc.
Product number
33627
Product name
Valganciclovir
Purity
98%purewithdatedHPLCUVchromatogram
Packaging
1mg
Price
$685
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004848
Product name
VALGANCICLOVIR
Purity
95.00%
Packaging
0.25G
Price
$764
Updated
2021/12/16
Matrix Scientific
Product number
097028
Product name
(2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate
Purity
95+%
Packaging
1g
Price
$807
Updated
2021/12/16
AK Scientific
Product number
Y0321
Product name
Valganciclovir
Packaging
1g
Price
$1139
Updated
2021/12/16
Matrix Scientific
Product number
097028
Product name
(2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate
Purity
95+%
Packaging
250mg
Price
$364
Updated
2021/12/16
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Valganciclovir Chemical Properties,Usage,Production

Uses

Antiviral.

Uses

Valganciclovir-d8, is the labeled analogue of Valganciclovir (V092000), a pro-drug of Ganciclovir, used in treatment of retro-virus.

Definition

ChEBI: The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine.

Indications

Valganciclovir (Valcyte) is the L-valyl ester prodrug of ganciclovir.

brand name

Valcyte (Roche).

Clinical Use

Oral valganciclovir is comparable to intravenous ganciclovir for the treatment and suppression of CMV retinitis in AIDS patients.

Drug interactions

Potentially hazardous interactions with other drugs
Antibacterials: increased risk of convulsions with imipenem-cilastatin.
Antivirals: possibly increased didanosine concentration; profound myelosuppression with zidovudine - avoid if possible.
Mycophenolate: possibly increased concentrations of both mycophenolic acid and ganciclovir.
Increased risk of myelosuppression with other myelosuppressive drugs.

Metabolism

Valganciclovir is well absorbed from the gastrointestinal tract and rapidly and extensively metabolised in the intestinal wall and liver to ganciclovir. Valganciclovir is eliminated in the urine as unchanged ganciclovir, mainly by glomerular filtration and also active tubular secretion.

Valganciclovir Preparation Products And Raw materials

Raw materials

Preparation Products

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Valganciclovir Suppliers

Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
6854
Advantage
65
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Shanghai Fuhe Chemistry Technology Co., Ltd.
Tel
0086-21-67651709
Fax
0086-21-67651705
Email
cfx759@hotmail.com
Country
China
ProdList
410
Advantage
57
Wuhan Fortuna Chemical Co., Ltd
Tel
027-027-59207852 13308628970
Fax
QQ3130921841
Email
buy@fortunachem.com
Country
China
ProdList
2893
Advantage
58
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12338
Advantage
58
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
GIHI CHEMICALS CO.,LTD
Tel
0086-571-86217390
Fax
0086-571-86217391
Email
Sales@gihichem.com
Country
China
ProdList
861
Advantage
58
Wuhan DKY Technology Co.,Ltd.
Tel
27-81302488 18007166089
Fax
027-81302088
Email
info@dkybpc.com
Country
China
ProdList
2024
Advantage
58
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View Lastest Price from Valganciclovir manufacturers

Sinoway Industrial co., ltd.
Product
Valganciclovir 175865-60-8
Price
US $0.00/Kg/Bag
Min. Order
2Kg/Bag
Purity
99% up, High Density
Supply Ability
20 tons
Release date
2021-07-14
Henan Aochuang Chemical Co.,Ltd.
Product
Valganciclovir 175865-60-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-29
Baoji Guokang Healthchem co.,ltd
Product
Valganciclovir 175865-60-8
Price
US $63.50-2698.40/KG
Min. Order
10g
Purity
99%
Supply Ability
200kg
Release date
2021-06-03

175865-60-8, ValganciclovirRelated Search:


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  • 2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester
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  • L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester
  • ValganciclovirQ: What is Valganciclovir Q: What is the CAS Number of Valganciclovir Q: What is the storage condition of Valganciclovir Q: What are the applications of Valganciclovir
  • 175865-60-8
  • 175680-60-8
  • C14H22N6O5
  • API