Valganciclovir

Product Name: Valganciclovir
CAS No.: 175865-60-8
Chemical Name: Valganciclovir
Synonyms: Valgancyclovir;Valganciclov;valganciclovir;Valganciclovir-d8;Valganciclovir-d8 (Mixture of Diastereomers);Valganciclovir & Valganciclovir Hydrochloride;Valganciclovir-d5 HCl (Mixture of diastetroMers);L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester;(2S)-2-((2-AMino-6-oxo-1H-purin-9(6H)-yl)Methoxy)-3-hydroxypropyl 2-aMino-3-Methylbutanoate;2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester
CBNumber: CB0855239
Molecular Formula: C14H22N6O5
Formula Weight: 354.36
MOL File: 175865-60-8.mol

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Valganciclovir Property

Density: 1.59±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 9.32±0.20(Predicted)
BCS Class: 3
InChI: InChI=1S/C14H22N6O5/c1-7(2)9(15)13(23)24-4-8(3-21)25-6-20-5-17-10-11(20)18-14(16)19-12(10)22/h5,7-9,21H,3-4,6,15H2,1-2H3,(H3,16,18,19,22)/t8?,9-/m0/s1
InChIKey: WPVFJKSGQUFQAP-GKAPJAKFSA-N
SMILES: C(OCC(OCN1C2=C(N=C1)C(=O)NC(N)=N2)CO)(=O)[C@H](C(C)C)N
CAS DataBase Reference: 175865-60-8(CAS DataBase Reference)

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Safety

Hazardous Substances Data: 175865-60-8(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Medical Isotopes, Inc.

Product number: 33627
Product name: Valganciclovir
Purity: 98%purewithdatedHPLCUVchromatogram
Packaging: 1mg
Price: $685
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0004848
Product name: VALGANCICLOVIR
Purity: 95.00%
Packaging: 0.25G
Price: $764
Updated: 2021/12/16

Matrix Scientific

Product number: 097028
Product name: (2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate
Purity: 95+%
Packaging: 1g
Price: $807
Updated: 2021/12/16

AK Scientific

Product number: Y0321
Product name: Valganciclovir
Packaging: 1g
Price: $1139
Updated: 2021/12/16

Matrix Scientific

Product number: 097028
Product name: (2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate
Purity: 95+%
Packaging: 250mg
Price: $364
Updated: 2021/12/16

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Valganciclovir Chemical Properties,Usage,Production

Uses

Antiviral.

Uses

Valganciclovir-d8, is the labeled analogue of Valganciclovir (V092000), a pro-drug of Ganciclovir, used in treatment of retro-virus.

Definition

ChEBI: The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine.

Indications

Valganciclovir (Valcyte) is the L-valyl ester prodrug of ganciclovir.

brand name

Valcyte (Roche).

Clinical Use

Oral valganciclovir is comparable to intravenous ganciclovir for the treatment and suppression of CMV retinitis in AIDS patients.

Drug interactions

Potentially hazardous interactions with other drugs
Antibacterials: increased risk of convulsions with imipenem-cilastatin.
Antivirals: possibly increased didanosine concentration; profound myelosuppression with zidovudine - avoid if possible.
Mycophenolate: possibly increased concentrations of both mycophenolic acid and ganciclovir.
Increased risk of myelosuppression with other myelosuppressive drugs.

Metabolism

Valganciclovir is well absorbed from the gastrointestinal tract and rapidly and extensively metabolised in the intestinal wall and liver to ganciclovir. Valganciclovir is eliminated in the urine as unchanged ganciclovir, mainly by glomerular filtration and also active tubular secretion.

Valganciclovir Preparation Products And Raw materials

Raw materials

Preparation Products

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Valganciclovir Suppliers

China 90 Europe 2 Germany 1 India 17 Italy 1 United Kingdom 1 United States 15 Global 127

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8836
Advantage: 52

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7195
Advantage: 65

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Shanghai Fuhe Chemistry Technology Co., Ltd.

Tel: 0086-21-67651709
Fax: 0086-21-67651705
Email: cfx759@hotmail.com
Country: China
ProdList: 410
Advantage: 57

Wuhan Fortuna Chemical Co., Ltd

Tel: 027-59207852 13308628970
Fax: QQ3130921841
Email: buy@fortunachem.com
Country: China
ProdList: 2866
Advantage: 58

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12335
Advantage: 58

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

GIHI CHEMICALS CO.,LTD

Tel: 0086-571-86217390
Fax: 0086-571-86217391
Email: Sales@gihichem.com
Country: China
ProdList: 860
Advantage: 58

Wuhan DKY Technology Co.,Ltd.

Tel: 27-81302488 18007166089
Fax: 027-81302088
Email: info@dkybpc.com
Country: China
ProdList: 2024
Advantage: 58

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View Lastest Price from Valganciclovir manufacturers

HangZhou RunYan Pharma Technology Co.,LTD.

Product: Valganciclovir 175865-60-8
Price: US $0.00-0.00/g
Min. Order: 10g
Purity: 99% HPLC
Supply Ability: 10000
Release date: 2024-09-11

Sinoway Industrial co., ltd.

Product: Valganciclovir 175865-60-8
Price: US $0.00/Kg/Bag
Min. Order: 2Kg/Bag
Purity: 99% up, High Density
Supply Ability: 20 tons
Release date: 2021-07-14

Henan Aochuang Chemical Co.,Ltd.

Product: Valganciclovir 175865-60-8
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-29

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Valganciclovir-d8

(2S)-2-((2-AMino-6-oxo-1H-purin-9(6H)-yl)Methoxy)-3-hydroxypropyl 2-aMino-3-Methylbutanoate

5-amino-3-[1-(hydroxymethyl)-2-(l-valyloxy)ethoxymethyl]-6,7- dihydro-3h-imidazo[4,5-d]pyrimidin-7-one

Valgancyclovir

Valganciclovir-d5 HCl (Mixture of diastetroMers)

Valganciclovir-d8 (Mixture of Diastereomers)

2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester

Valganciclov

L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester

ValganciclovirQ: What is Valganciclovir Q: What is the CAS Number of Valganciclovir Q: What is the storage condition of Valganciclovir Q: What are the applications of Valganciclovir

175865-60-8

175680-60-8

C14H22N6O5

API