Valganciclovir
- Product Name
- Valganciclovir
- CAS No.
- 175865-60-8
- Chemical Name
- Valganciclovir
- Synonyms
- Valgancyclovir;Valganciclov;valganciclovir;Valganciclovir-d8;Valganciclovir-d8 (Mixture of Diastereomers);Valganciclovir & Valganciclovir Hydrochloride;Valganciclovir-d5 HCl (Mixture of diastetroMers);L-Valine, 2-[(2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]-3-hydroxypropyl ester;(2S)-2-((2-AMino-6-oxo-1H-purin-9(6H)-yl)Methoxy)-3-hydroxypropyl 2-aMino-3-Methylbutanoate;2-amino-3-methylbutanoic acid [2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-3-hydroxypropyl] ester
- CBNumber
- CB0855239
- Molecular Formula
- C14H22N6O5
- Formula Weight
- 354.36
- MOL File
- 175865-60-8.mol
Valganciclovir Property
- Density
- 1.59±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 9.32±0.20(Predicted)
- BCS Class
- 3
- CAS DataBase Reference
- 175865-60-8(CAS DataBase Reference)
Safety
- Hazardous Substances Data
- 175865-60-8(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 33627
- Product name
- Valganciclovir
- Purity
- 98%purewithdatedHPLCUVchromatogram
- Packaging
- 1mg
- Price
- $685
- Updated
- 2021/12/16
- Product number
- API0004848
- Product name
- VALGANCICLOVIR
- Purity
- 95.00%
- Packaging
- 0.25G
- Price
- $764
- Updated
- 2021/12/16
- Product number
- 097028
- Product name
- (2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $807
- Updated
- 2021/12/16
- Product number
- Y0321
- Product name
- Valganciclovir
- Packaging
- 1g
- Price
- $1139
- Updated
- 2021/12/16
- Product number
- 097028
- Product name
- (2S)-2-((2-Amino-6-oxo-1H-purin-9(6H)-yl)methoxy)-3-hydroxypropyl 2-amino-3-methylbutanoate
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $364
- Updated
- 2021/12/16
Valganciclovir Chemical Properties,Usage,Production
Uses
Antiviral.
Uses
Valganciclovir-d8, is the labeled analogue of Valganciclovir (V092000), a pro-drug of Ganciclovir, used in treatment of retro-virus.
Definition
ChEBI: The L-valinyl ester of ganciclovir, into which it is rapidly converted by intestinal and hepatic esterases. It is a synthetic analogue of 2'-deoxyguanosine.
Indications
Valganciclovir (Valcyte) is the L-valyl ester prodrug of ganciclovir.
brand name
Valcyte (Roche).
Clinical Use
Oral valganciclovir is comparable to intravenous ganciclovir for the treatment and suppression of CMV retinitis in AIDS patients.
Drug interactions
Potentially hazardous interactions with other drugs
Antibacterials: increased risk of convulsions with
imipenem-cilastatin.
Antivirals: possibly increased didanosine
concentration; profound myelosuppression with
zidovudine - avoid if possible.
Mycophenolate: possibly increased concentrations of
both mycophenolic acid and ganciclovir.
Increased risk of myelosuppression with other
myelosuppressive drugs.
Metabolism
Valganciclovir is well absorbed from the gastrointestinal tract and rapidly and extensively metabolised in the intestinal wall and liver to ganciclovir. Valganciclovir is eliminated in the urine as unchanged ganciclovir, mainly by glomerular filtration and also active tubular secretion.
Valganciclovir Preparation Products And Raw materials
Raw materials
Preparation Products
Valganciclovir Suppliers
View Lastest Price from Valganciclovir manufacturers
- Product
- Valganciclovir 175865-60-8
- Price
- US $0.00/Kg/Bag
- Min. Order
- 2Kg/Bag
- Purity
- 99% up, High Density
- Supply Ability
- 20 tons
- Release date
- 2021-07-14
- Product
- Valganciclovir 175865-60-8
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-29
- Product
- Valganciclovir 175865-60-8
- Price
- US $63.50-2698.40/KG
- Min. Order
- 10g
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2021-06-03